Results 51 to 60 of about 3,138,466 (347)

From omics to AI—mapping the pathogenic pathways in type 2 diabetes

FEBS Letters, EarlyView.
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan, Lu Qi, Pierre Zalloua   +2 more
wiley   +1 more source

On extended Kalman filters with augmented state vectors for the stator flux estimation in SPMSMs [PDF]

, 2010
The demand for highly dynamic electrical drives, characterized by high quality torque control, in a wide variety of applications has grown tremendously during the past decades.
Boel, René, Melkebeek, Jan, Vyncke, Thomas   +2 more
core   +2 more sources

The anabolic steroid stanozolol is a potent inhibitor of human MutT homolog 1

FEBS Letters, EarlyView.
MutT homolog 1 (MTH1) is a member of the NUDIX superfamily of enzymes and is an anticancer drug target. We show that stanozolol (Stz), an anabolic steroid, is an unexpected nanomolar inhibitor of MTH1. The X‐ray crystal structure of the human MTH1–Stz complex reveals a unique binding scaffold that could be utilized for future inhibitor development ...
Emma Scaletti Hutchinson, Robert Gustafsson Westergren, Ingrid Almlöf, Ann‐Sofie Jemth, Martin Scobie, Ulrika Warpman Berglund, Thomas Helleday, Pål Stenmark   +7 more
wiley   +1 more source

Velocity vector control system augmented with direct lift control [PDF]

, 1981
A pilot-controlled stability control system that employs direct lift control (spoiler control) with elevator control to control the flight path angle of an aircraft is described.
Kelly, W. W., Tisdale, H. F., Sr.
core   +1 more source

Mating of unfed, engorged, and partially to fully gravid Aedes aegypti (Diptera: Culicidae) female mosquitoes in producing viable eggs

Parasites & Vectors
Background Understanding the relationship between blood-feeding and mating is important in effectively managing the most well-adapted vector insect, Aedes aegypti (Linnaeus).
Muniaraj Mayilsamy, Surendiran Subramani, Rajamannar Veeramanoharan, Asifa Vijayakumar, Amuthalingam T. Asaithambi, Arthi Murugesan, Nandhakumar Selvaraj, Vijayakumar Balakrishnan, Paramasivan Rajaiah   +8 more
doaj   +1 more source

ERBIN limits epithelial cell plasticity via suppression of TGF‐β signaling

FEBS Letters, EarlyView.
In breast and lung cancer patients, low ERBIN expression correlates with poor clinical outcomes. Here, we show that ERBIN inhibits TGF‐β‐induced epithelial‐to‐mesenchymal transition in NMuMG breast and A549 lung adenocarcinoma cell lines. ERBIN suppresses TGF‐β/SMAD signaling and reduces TGF‐β‐induced ERK phosphorylation.
Chao Li, Gerard van der Zon, Peter ten Dijke, Tong Shen   +3 more
wiley   +1 more source

Study of vortex valve for medium temperature solid propellants [PDF]

, 1966
Fluid state vortex valve secondary injection control system shows considerable promise for future application to solid propellant rocket engine thrust vector control.
Holt, W. D., Rivard, J. G.
core   +1 more source

Molecular identification of wild caught phlebotomine sand flies (Diptera, Psychodidae) by mitochondrial DNA barcoding in India

Scientific Reports
Sand flies are medically important insects with diverse distributions and roles in pathogen transmission. Globally, over a thousand species have been documented, with Indian sand fly fauna currently comprising 71 species.
Harish Kumar Shah, P. A. Fathima, Bhavna Gupta, Manju Rahi, Prasanta Saini   +4 more
doaj   +1 more source

Isolation of Borrelia miyamotoi and other Borreliae using a modified BSK medium

Scientific Reports, 2021
Borrelia spirochetes are the causative agents of Lyme borreliosis (LB) and relapsing fever (RF). Despite the steady rise in infections and the identification of new species causing human illness over the last decade, isolation of borreliae in culture has
Adam J. Replogle, Christopher Sexton, John Young, Luke C. Kingry, Martin E. Schriefer, Marc Dolan, Tammi L. Johnson, Neeta P. Connally, Kerry A. Padgett, Jeannine M. Petersen   +9 more
doaj   +1 more source

Vector Control Strategies

, 2023
Vector-borne diseases, mainly dengue and malaria, are serious public health problems in the world; for the control of Aedes and Anopheles mosquitoes, there are several strategies such as biological, genetic, chemical, physical, and cultural. For the application of these control strategies, it is important to take into account the integrated vector ...
Wilber, Gómez-Vargas,, Esteban, Zapata-Úsuga, Giovani   +1 more
openaire   +2 more sources