Results 81 to 90 of about 3,138,466 (347)

Acute undifferentiated febrile illness in a traveler returning from Burkina Faso, West Africa to Puducherry, India- a case report

BMC Infectious Diseases
Background Imported malaria remains a significant diagnostic challenge, particularly in regions approaching elimination. This case report is novel in its exploration of the complexities involved in diagnosing malaria imported from a high-endemic area to ...
Srikanth Srirama, Krishan Kumar Sihag, Anand Kumar Chandrasekaran, Neethi Prasannan Latha, Waseema Arif, Balaji Sampath Kumar, Panneer Devaraju   +6 more
doaj   +1 more source

MicroRNA 196a contributes to the aggressiveness of esophageal adenocarcinoma through the MYC/TERT/NFκB axis

Molecular Oncology, EarlyView.
mir‐196a promotes Esophagus Adenocarcinoma aggressiveness. On one hand, mir‐196a targets the valosin‐containing protein (VCP) mRNA, causing the accumulation of c‐MYC protein that leads to high amounts of TERT. On the other hand, mir‐196a targets the inhibitor of NFκB (NFKBIA).
Jesús García‐Castillo, Carlos M. Martínez‐Cáceres, Manuel Bernabé‐García, Vicente Munitiz, David Ruiz de Angulo, Pascual Parrilla, Ángeles Ortiz, Luisa F. Martínez de Haro, María L. Cayuela   +8 more
wiley   +1 more source

TRPM8 levels determine tumor vulnerability to channel agonists

Molecular Oncology, EarlyView.
TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo, Francesco Giuseppe Carbone, Kristi Buzo, Nicole Annesi, Sacha Genovesi, Annalisa Lorenzato, Karen Widmann, Michela Libergoli, Elisa Marmocchi, Giovanni Bertalot, Alberto Brolese, Mauro Giulio Papotti, Luca Molinaro, Orazio Caffo, Mattia Barbareschi, Alberto Bardelli, Alessandro Romanel, Sabrina Arena, Andrea Lunardi   +18 more
wiley   +1 more source

Biological vector control with the sterile insect technique for the chilungunya disease [PDF]

, 2010
Chikungunya is a vector-borne Disease, usually localized in Asia and East-Africa, with Aedes albopictus mosquito as the principal vector for the Chikungunya virus.
Dumont, Yves, Tchuenche, J.M.
core  

Impact of climatic factors on the occurrence of malaria in hyper, high, moderate and low endemic States in India from 1995 to 2023

Malaria Journal
Background Malaria has been surging in India for the past 3 years after reaching the recorded low in 2021. Among the possible reasons for this unexpected surge of cases, such as insufficient surveillance, slow and aggregated data reporting, endemic ...
Muniaraj Mayilsamy, Rajagopal Parthasarathy, Rajamannar Veeramanoharan, Paramasivan Rajaiah   +3 more
doaj   +1 more source

The way forward for vector control

Science, 2017
Pesticide resistance must be countered to control insects that serve as disease ...
openaire   +4 more sources

A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner

Molecular Oncology, EarlyView.
We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp, Wouter P. R. Verdurmen, Jonas V. Schaefer, Kari Kopra, Gabriela Nagy‐Davidescu, Elodie Richard, Marie‐Julie Nokin, Patrick Ernst, Rastislav Tamaskovic, Martin Schwill, Ralph Degen, Claudia Scholl, David Santamaria, Andreas Plückthun   +13 more
wiley   +1 more source

Vector control for the chikungunya disease: chemical control versus biological control: a mathematical point of view. [PDF]

, 2010
The aim of this talk is to present recent investigations on the Chikungunya Disease that hitted Réunion Island, a French territory in Indian Ocean, in 2005 and 2006. Chikungunya is a vectorborne Disease, usually localized in Asia and East-Africa. In 2005,
Dumont, Yves
core  

Report of a new species of sand fly, Phlebotomus (Anaphlebotomus) ajithii n. sp. (Diptera: Psychodidae), from Western Ghats, India

Parasites & Vectors
Background Western Ghats is a biodiversity treasure trove with reports of indigenous leishmaniasis cases. Hence, systematic sand fly surveillance was carried out among the tribal population. The present study reports a novel sand fly species, Phlebotomus
Harish Kumar Shah, P. A. Fathima, Jose Jicksy, Prasanta Saini   +3 more
doaj   +1 more source

Hard Ticks as Vectors: The Emerging Threat of Tick-Borne Diseases in India

Pathogens
Hard ticks (Ixodidae) play a critical role in transmitting various tick-borne diseases (TBDs), posing significant global threats to human and animal health. Climatic factors influence the abundance, diversity, and vectorial capacity of tick vectors.
Nandhini Perumalsamy, Rohit Sharma, Muthukumaravel Subramanian, Shriram Ananganallur Nagarajan   +3 more
doaj   +1 more source