Results 41 to 50 of about 3,337 (213)

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

Direct Vector Control With Fuzzy Current Controller for Three-phase Induction Motor

open access: yesEletrônica de Potência, 2013
This article proposes a Direct Vector Control (DVC) method with a Fuzzy Logic Current Controller (FLCC) for three-phase induction motor. The conventional DVC method has two PI current controllers.
Jos´e L. Azcue-Puma   +2 more
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

open access: yesFEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara   +3 more
wiley   +1 more source

Dual-Vector Model Predictive Current Control with Entire-Time-Domain Current Harmonic Optimization and Robust Control Strategy

open access: yesEnergies
This article proposes a robust dual-vector model predictive control (RDVMPC) strategy for high-power three-level inverters, specifically designed to optimize current harmonics.
Dahui Guo   +5 more
doaj   +1 more source

MRAS Based Sensorless and Sensor Vector Control and Smooth Transient Between Them

open access: yesCommunications, 2011
Dynamic control, like vector control is an essential feature of every modern AC drive. In some cases it might be very important to provide continuous operation in case of encoder failure.
Jakub Vonkomer, Milan Zalman
doaj   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

Virtual Frequency Construction-Based Vector Current Control for Grid-Tied Inverter Under Imbalanced Voltage

open access: yesIEEE Access, 2020
This paper proposes a fast phase capture (FPC) scheme and applies it to the control strategy of grid-tied inverters under imbalanced voltage. Firstly, a method for quickly extracting sequence components of power signals is derived through the symmetrical
Wu Binbing   +4 more
doaj   +1 more source

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