Results 61 to 70 of about 17,059,498 (307)

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

FEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell, Thomas Walther, Egbert Hoiczyk   +2 more
wiley   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

FEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav, Bogdan I. Florea, Sebastian Geibel   +2 more
wiley   +1 more source

Current vector control pipeline.

, 2016
Current vector control pipeline.
David Bell (38377), Janet Hemingway (23878), Rima Shretta (3212160), Nicole Achee (3212163), Gao Qi (3212157), Abdoulaye A. Djimdé (2227663), Timothy N. C. Wells (422572)   +6 more
core   +1 more source

Clustering of vector control interventions has important consequences for their effectiveness : a modelling study [PDF]

, 2014
Vector control interventions have resulted in considerable reductions in malaria morbidity and mortality. When universal coverage cannot be achieved for financial or logistical reasons, the spatial arrangement of vector control is potentially important ...
Chitnis, Nakul, Penny, Melissa A, Melissa A Penny, Nakul Chitnis, Lutambi, Angelina Mageni, Angelina Mageni Lutambi, Briët, Olivier J. T., Briët, Olivier J T, Smith, Thomas A., Olivier J T Briët, Smith, Thomas A, Thomas A Smith, Penny, Melissa A.   +12 more
core   +2 more sources

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

Vector control in a malaria epidemic occurring within a complex emergency situation in Burundi: a case study. [PDF]

, 2007
BACKGROUND: African highlands often suffer of devastating malaria epidemics, sometimes in conjunction with complex emergencies, making their control even more difficult. In 2000, Burundian highlands experienced a large malaria outbreak at a time of civil
Baza, D., Reid, T., Van Herp, M, Baza Dismas, Maes, P., D'Alessandro Umberto, Baza, D, Baza, Dismas, Van Bortel Wim, d' Alessandro, Umberto, Maes Peter, Protopopoff, Natacha, Reid, Tony, Van Bortel, W., Maes, Peter, D'Alessandro, U., Reid Tony, Coosemans Marc, Protopopoff, N., Van Herp, Michel, Coosemans, Marc, D'Alessandro, Umberto, Van Herp, M., Coosemans, M, Maes, P, Coosemans, M., Van Bortel, W, D'Alessandro, U, Van Bortel, Wim, Protopopoff Natacha, Reid, T, Van Herp Michel, Protopopoff, N   +32 more
core   +1 more source

Dual-Vector Model Predictive Current Control with Entire-Time-Domain Current Harmonic Optimization and Robust Control Strategy

Energies
This article proposes a robust dual-vector model predictive control (RDVMPC) strategy for high-power three-level inverters, specifically designed to optimize current harmonics.
Dahui Guo, Jian Yang, Hanbin Zhou, Qian Huang, Mi Dong, Liqing Liao   +5 more
doaj   +1 more source

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

FEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos, Antonia Petropoulou, Alexandra Anastogianni, Angelina Bania, Vassilis Stamatakis, Argyris Alexiou, Chi‐Ping Day, Glenn Merlino, Katerina Grafanaki, Constantinos Stathopoulos   +9 more
wiley   +1 more source

Power Limitation Control for a PMSG-Based Marine Current Turbine at High Tidal Speed and Strong Sea State [PDF]

, 2013
This paper deals with the control strategies for a fixed-pitch marine current turbine (MCT) when the marine current speed exceeds the rated value corresponding to the rated power of generator and converter.
SCUILLER, Franck, CHARPENTIER, Jean-Frederic, BENBOUZID, Mohamed, ZHOU, Zhibin, Frédéric Charpentier, Jean, Mohamed Benbouzid, Zhibin Zhou, Franck Scuiller, TANG, Tianhao, Tianhao Tang, Jean Frederic Charpentier   +10 more
core   +1 more source