A new species in the major malaria vector complex sheds light on reticulated species evolution [PDF]
, 2019 Complexes of closely related species provide key insights into the rapid and independent evolution of adaptive traits. Here, we described and studied Anopheles fontenillei sp.n., a new species in the Anopheles gambiae complex that we recently discovered ...
Akone-Ella O. +11 more
core +1 more source
Molecular Insights into the Flavivirus Replication Complex
Viruses, 2021 Flaviviruses are vector-borne RNA viruses, many of which are clinically relevant human viral pathogens, such as dengue, Zika, Japanese encephalitis, West Nile and yellow fever viruses.
Kaïn van den Elsen, J. Quek, D. Luo
semanticscholar +1 more source
A Substrate-induced Biotin Binding Pocket in the Carboxyltransferase Domain of Pyruvate Carboxylase [PDF]
, 2013 Biotin-dependent enzymes catalyze carboxyl transfer reactions by efficiently coordinating multiple reactions between spatially distinct active sites. Pyruvate carboxylase (PC), a multifunctional biotin-dependent enzyme, catalyzes the bicarbonate- and ...
Lietzan, Adam D, Maurice, Martin St.
core +2 more sources
A non-homogeneous dynamic Bayesian network with sequentially coupled interaction parameters for applications in systems and synthetic biology [PDF]
, 2012 An important and challenging problem in systems biology is the inference of gene regulatory networks from short non-stationary time series of transcriptional profiles.
Grzegorczyk, M., Husmeier, D.
core +2 more sources
Optimizing tick artificial membrane feeding for Ixodes scapularis
Scientific Reports, 2023 Artificial membrane feeding (AMF) is a powerful and versatile technique with a wide range of applications in the study of disease vectors species. Since its first description, AMF has been under constant optimization and standardization for different ...
Melina Garcia Guizzo +5 more
doaj +1 more source
Physical constraints on accuracy and persistence during breast cancer cell chemotaxis [PDF]
, 2019 Directed cell motion in response to an external chemical gradient occurs in many biological phenomena such as wound healing, angiogenesis, and cancer metastasis.
Han, Bumsoo +4 more
core +4 more sources
Malaria Journal, 2019 Background Anopheles sinensis is the primary vector of vivax malaria in China and its control is under great threat as the development of insecticide resistance.
Zhengbo He +6 more
doaj +1 more source
A topological approach for protein classification
, 2015 Protein function and dynamics are closely related to its sequence and structure. However prediction of protein function and dynamics from its sequence and structure is still a fundamental challenge in molecular biology.
Cang, Zixuan +5 more
core +1 more source
A Novel Peptide-Based SILAC Method to Identify the Posttranslational Modifications Provides Evidence for Unconventional Ubiquitination in the ER-Associated Degradation Pathway. [PDF]
, 2013 The endoplasmic reticulum-associated degradation (ERAD) pathway is responsible for disposing misfolded proteins from the endoplasmic reticulum by inducing their ubiquitination and degradation.
Anania, Veronica +4 more
core +3 more sources
Parasites & Vectors, 2017 Background Phenol oxidases (POs) catalyze the oxidation of dopa and dopamine to melanin, which is crucial for cuticle formation and innate immune maintenance in insects.
Ming-Hui Du +6 more
doaj +1 more source