Results 51 to 60 of about 1,117,643 (337)

Sand flies: Basic information on the vectors of leishmaniasis and their interactions with Leishmania parasites

Communications Biology, 2022
In this review, numerous aspects of sand flies as vectors of Leishmania parasites—from biology to the vector parasite interactions—are discussed.
Pedro Cecílio, Anabela Cordeiro-da-Silva, Fabiano Oliveira   +2 more
doaj   +1 more source

A sand fly salivary protein acts as a neutrophil chemoattractant

Nature Communications, 2021
Immune mimicry has been shown in chemokine like moieties from bacteria and viruses. Here, the authors characterise a sand fly salivary protein that induces neutrophil chemotaxis and explore its impact in a model of parasitic infection.
Anderson B. Guimaraes-Costa, John P. Shannon, Ingrid Waclawiak, Jullyanna Oliveira, Claudio Meneses, Waldione de Castro, Xi Wen, Joseph Brzostowski, Tiago D. Serafim, John F. Andersen, Heather D. Hickman, Shaden Kamhawi, Jesus G. Valenzuela, Fabiano Oliveira   +13 more
doaj   +1 more source

Graph Representation Learning in Biomedicine [PDF]

, 2021
Biomedical networks (or graphs) are universal descriptors for systems of interacting elements, from molecular interactions and disease co-morbidity to healthcare systems and scientific knowledge. Advances in artificial intelligence, specifically deep learning, have enabled us to model, analyze, and learn with such networked data. In this review, we put
arxiv   +1 more source

Suppression of Laccase 2 severely impairs cuticle tanning and pathogen resistance during the pupal metamorphosis of Anopheles sinensis (Diptera: Culicidae)

Parasites & Vectors, 2017
Background Phenol oxidases (POs) catalyze the oxidation of dopa and dopamine to melanin, which is crucial for cuticle formation and innate immune maintenance in insects.
Ming-Hui Du, Zheng-Wen Yan, You-Jin Hao, Zhen-Tian Yan, Feng-Ling Si, Bin Chen, Liang Qiao   +6 more
doaj   +1 more source

Modification of contact avoidance behaviour associated with pyrethroid resistance in Anopheles sinensis (Diptera: Culicidae)

Malaria Journal, 2019
Background Anopheles sinensis is the primary vector of vivax malaria in China and its control is under great threat as the development of insecticide resistance.
Zhengbo He, Jing Zhang, Zongpan Shi, Jingang Liu, Jingjing Zhang, Zhentian Yan, Bin Chen   +6 more
doaj   +1 more source

Centrin-deficient Leishmania mexicana confers protection against Old World visceral leishmaniasis

npj Vaccines, 2022
Leishmaniasis is one of the top neglected tropical diseases with significant morbidity and mortality in low and middle-income countries (LMIC). However, this disease is also spreading in the developed world.
Subir Karmakar, Greta Volpedo, Wen-Wei Zhang, Patrick Lypaczewski, Nevien Ismail, Fabiano Oliveira, James Oristian, Claudio Meneses, Sreenivas Gannavaram, Shaden Kamhawi, Shinjiro Hamano, Jesus G. Valenzuela, Greg Matlashewski, Abhay R. Satoskar, Ranadhir Dey, Hira L. Nakhasi   +15 more
doaj   +1 more source

Hybridization in parasites: consequences for adaptive evolution, pathogenesis and public health in a changing world [PDF]

, 2015
[No abstract ...
A Berry, A Koukounari, AJ Norton, AR Laird, B Schelkle, BL Webster, BL Webster, BL Webster, BR Grant, C Astrom, C Gyles, CA Machado, CD Criscione, CM Brasier, CM Lively, CM Lively, CS Clarkson, CS Wondji, D Menge, D Rollinson, D Weetman, DB Dunams-Morel, DE Neafsey, Deborah F. Smith, DR Brooks, DR Dittrich-Reed, E Inbar, E Mancini, E Redman, E Strauch, EH Stukenbrock, EJ Baack, GL Nichols, Glenn F Rall, H Krehenwinkel, H Ochman, H Ochman, HD Mawejje, HJ Müller, HV Pates, I Goodhead, J Boissier, J Davies, J Hawks, J Mallet, J Mavarez, JA Coyne, JA Patz, JC Semenza, JM Kelly, Joanne P. Webster, JP Webster, JP Webster, JT Detwiler, Kayla C. King, KD Lafferty, LA Messenger, LA Messenger, LAT Tchuente, LC Norris, LH Rieseberg, LH Rieseberg, M Arnold, M Lynch, M Schumer, M Worobey, MA Miles, MA Nowak, MB Rogers, MB Rogers, MC Fontaine, ME Grigg, MF Dybdahl, MG Taylor, Michael A. Brockhurst, MJ Gibbs, ML Arnold, ML Arnold, ML Steinauer, MW Gaunt, NH Barton, NR Sturm, NS Akopyants, O Seehausen, P Martens, P Volf, P Volf, PW Hedrick, R Abbott, RA Farrer, RB Stelkens, RB Stelkens, RDH Barrett, Rike B. Stelkens, RS Ramiro, S Edmands, S Hales, S Manguin, S Moore, T Dobzhansky, T Huyse, T Huyse, TH Le, U Chaudhry, W Alves, W Choochote, W Li, Y Lee, Y Song   +108 more
core   +2 more sources

Allelic diversity of merozoite surface protein genes (msp1 and msp2) and clinical manifestations of Plasmodium falciparum malaria cases in Aceh, Indonesia

Malaria Journal, 2021
Background The malaria control programme in Indonesia has successfully brought down malaria incidence in many parts in Indonesia, including Aceh Province.
Kurnia Fitri Jamil, Nandha Rizki Pratama, Sylvia Sance Marantina, Harapan Harapan, Muhammad Riza Kurniawan, Tjut Mariam Zanaria, Jontari Hutagalung, Ismail Ekoprayitno Rozi, Puji Budi Setia Asih, Supargiyono, Din Syafruddin   +10 more
doaj   +1 more source

Taurine promotes glucagon‐like peptide‐1 secretion in enteroendocrine L cells

FEBS Letters, EarlyView.
Taurine, a sulfur‐containing amino acid, is likely taken up by enteroendocrine L cells via the taurine transporter. This process increases the levels of cytosolic ATP. The increase in intracellular Ca2+ concentrations and glucagon‐like peptide‐1 secretion through membrane depolarization is caused by the closure of ATP‐sensitive potassium channels ...
Yuri Osuga, Kazuki Harada, Takuya Yamauchi, Tetsuya Kitaguchi, Masami Yokota Hirai, Mitsuharu Matsumoto, Takashi Tsuboi   +6 more
wiley   +1 more source

An essential function for the ATR-Activation-Domain (AAD) of TopBP1 in mouse development and cellular senescence [PDF]

, 2013
ATR activation is dependent on temporal and spatial interactions with partner proteins. In the budding yeast model, three proteins – Dpb11TopBP1, Ddc1Rad9 and Dna2 - all interact with and activate Mec1ATR.
A Aguilera, A Balestrini, A Ciccia, A de Klein, A Kumagai, A Kumagai, A Mavrou, Anja Krueger, Antony M. Carr, C Cotta-Ramusino, Christopher Bruhn, Cong Liu, D Boos, D Branzei, D Cortez, DA Mordes, DA Mordes, EA Nam, EJ Brown, EJ Brown, FD Sweeney, H Wang, HL Ball, HY Yoo, J Lee, JE Kim, K Furuya, K Liu, K Liu, K Liu, K Liu, K Yamane, KA Cimprich, L Zou, L Zou, LA Lindsey-Boltz, LI Toledo, M Qu, Marshall S. Horwitz, O Limbo, P Bork, P Zegerman, PJ Woolf, R Gruber, RJ Edwards, S Biton, S Delacroix, S Kumar, S Liu, S Mochida, SJ Lin, SP Jackson, T Usui, Tang-Liang Li, V Garcia, VM Navadgi-Patil, VM Navadgi-Patil, WooKee Min, X Xu, X Yu, Y Jeon, Y Jeon, Y Lee, Z You, Z Zhou, Zhao-Qi Wang, Zhong-Wei Zhou, ZQ Wang   +67 more
core   +3 more sources