Results 71 to 80 of about 36,083 (304)

GNAQPMS v1.1: accelerating the Global Nested Air Quality Prediction Modeling System (GNAQPMS) on Intel Xeon Phi processors [PDF]

open access: yesGeoscientific Model Development, 2017
The Global Nested Air Quality Prediction Modeling System (GNAQPMS) is the global version of the Nested Air Quality Prediction Modeling System (NAQPMS), which is a multi-scale chemical transport model used for air quality forecast and atmospheric ...
H. Wang   +14 more
doaj   +1 more source

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

open access: yesFEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson   +6 more
wiley   +1 more source

An application study of parallel processing to the particle transport simulation

open access: yesComputer Assisted Methods in Engineering and Science, 2023
New methods of the neutron and photon transport Monte Carlo simulation suitable for vector computers have been investigated and general purpose multigroup and continuous energy codes have been developed. On vector supercomputers, the codes achieved high
Makoto Sasaki   +2 more
doaj  

Extending the NOEL-V Platform with a RISC-V Vector Processor for Space Applications

open access: yes, 2023
This paper describes the work carried out to extend the NOEL-V platform to include data-level parallelism (DLP) by implementing an integer subset of the RISC-V Vector Extension.
Menicucci, A. (author)   +3 more
core   +1 more source

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

open access: yesFEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara   +3 more
wiley   +1 more source

A CORDIC like processor for computation of arctangent and absolute magnitude of a vector

open access: yes, 2004
In this paper, we propose a CORDIC like algorithm for computing absolute magnitude of a vector and its corresponding phase angle. It eliminates scale factor compensation step as well as the addition/subtraction operation along the z datapath.
Troya, Alfonso   +4 more
core  

Rapid Codesign of a Soft Vector Processor and its Compiler

open access: yes, 2014
Despite a decade of activity in the development of soft vector processors for FPGAs, high-level language support remains thin. We attribute this problem to a design method in which the high-level vector programming interface is only really considered ...
Simon W. Moore, Matthew Naylor
core   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

The Vector Processor

open access: yes, 1990
The Vector Processor is a Single-Instruction Multiple-Data (SIMD) parallel processing system based on the IBM PC/XT microcomputer. This system is designed for the purpose of economically achieving maximum speed in the computer execution of scientific and
Chen, Jianmin
core  

Mixed‐class J‐domain protein scaffolds promote expanded aggregate handling and multivalent Hsp70 engagement during functional disaggregase assembly

open access: yesFEBS Letters, EarlyView.
Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley   +1 more source

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