Results 61 to 70 of about 417,841 (308)

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

open access: yesFEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan   +6 more
wiley   +1 more source

Autophagosome marker, LC3, is released extracellularly via several distinct pathways

open access: yesFEBS Open Bio, EarlyView.
This study establishes a novel HiBiT‐tagging system for ultrasensitive detection of LC3, revealing multiple pathways for its extracellular secretion. It demonstrates that LC3 is released via both autophagy‐dependent and ‐independent mechanisms, including a novel route for nonlipidated LC3‐I.
Koki Saito   +3 more
wiley   +1 more source

Generalized space vector controls for MLZSI

open access: yesAin Shams Engineering Journal, 2015
This paper proposes two advanced algorithms for multilevel Z-source inverter (MLZSI), which employ space vector control (SVC) as control algorithm of cascaded H-bridge multilevel Z-source inverter; where output voltage is achieved by summing the output ...
Aida Baghbany Oskouei   +1 more
doaj   +1 more source

On generic homogeneous vector fields

open access: yesИзвестия высших учебных заведений. Поволжский регион: Физико-математические науки, 2022
Background. The study of dynamical systems with symmetry is of both theoretical and applied interest. Phase portraits of dynamical systems defined by homogeneous vector fields are invariant with respect to the phase space dilation group.
V.Sh. Roytenberg
doaj   +1 more source

ATP13A2 is involved in intracellular polyamine transport in lung epithelial cells

open access: yesFEBS Open Bio, EarlyView.
Spermidine transport in lung epithelial cells involves the polyamine transporter ATP13A2. Cell proliferation is associated with the upregulation of ATP13A2. Polyamines are present in all living cells and are implicated in various crucial cellular processes such as proliferation, apoptosis and autophagy.
Yuta Hatori   +8 more
wiley   +1 more source

Infinite dimensional linear groups with a spacious family of $G$-invariant subspaces [PDF]

open access: yesМатематичні Студії, 2013
Let $F$ be a field, $A$ be a vector space over $F$, $GL (F, A)$ be the group of all automorphisms of the vector space $A$. If $B leq A$ then denote by $mathop{m Core}_G (B)$ the largest $G$-invariant subspace of~$B$.
A. V. Sadovnichenko
doaj  

Model of current space vector control

open access: yesMokslas: Lietuvos Ateitis, 2010
Space vector control Simulink model is developed and investigated. Physical phenomena occurring in AC motor during mentioned control usage and results are discussed. Short circuit mode is investigated.
Robertas Janickas
doaj   +1 more source

TMC4 localizes to multiple taste cell types in the mouse taste papillae

open access: yesFEBS Open Bio, EarlyView.
Transmembrane channel‐like 4 (TMC4), a voltage‐dependent chloride channel, plays a critical role in amiloride‐insensitive salty taste transduction. TMC4 is broadly expressed in all mature taste cell types, suggesting a possible involvement of multiple cell types in this pathway.
Momo Murata   +6 more
wiley   +1 more source

A Duty Cycle Space Vector Modulation Strategy for a Three-to-Five Phase Direct Matrix Converter

open access: yesEnergies, 2018
The duty cycle space vector (DCSV) modulation strategy is of universal significance, and the method can be utilized for different modulation approaches.
Rutian Wang   +3 more
doaj   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

open access: yesFEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani   +6 more
wiley   +1 more source

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