Results 61 to 70 of about 8,311,474 (361)

Insights into pegRNA design from editing of the cardiomyopathy‐associated phospholamban R14del mutation

open access: yesFEBS Letters, EarlyView.
This study reveals how prime editing guide RNA (pegRNA) secondary structure and reverse transcriptase template length affect prime editing efficiency in correcting the phospholamban R14del cardiomyopathy‐associated mutation. Insights support the design of structurally optimized enhanced pegRNAs for precise gene therapy.
Bing Yao   +7 more
wiley   +1 more source

"Massive" vector field in de Sitter space

open access: yes, 1999
We present in this paper a covariant quantization of the ``massive'' vector field on de Sitter (dS) space based on analyticity in the complexified pseudo-Riemanian manifold.
Gazeau, J-P., Takook, M. V.
core   +1 more source

Ontologically Grounded Multi-sense Representation Learning for Semantic Vector Space Models

open access: yesNorth American Chapter of the Association for Computational Linguistics, 2015
Words are polysemous. However, most approaches to representation learning for lexical semantics assign a single vector to every surface word type. Meanwhile, lexical ontologies such as WordNet provide a source of complementary knowledge to distributional
S. Jauhar, Chris Dyer, E. Hovy
semanticscholar   +1 more source

MADNESS IN VECTOR SPACES [PDF]

open access: yesThe Journal of Symbolic Logic, 2019
AbstractWe consider maximal almost disjoint families of block subspaces of countable vector spaces, focusing on questions of their size and definability. We prove that the minimum infinite cardinality of such a family cannot be decided in ZFC and that the “spectrum” of cardinalities of mad families of subspaces can be made arbitrarily large, in analogy
openaire   +4 more sources

TRAF2 binds to TIFA via a novel motif and contributes to its autophagic degradation

open access: yesFEBS Letters, EarlyView.
TRAF family members couple receptor signalling complexes to downstream outputs, but how they interact with these complexes is not always clear. Here, we show that during ADP‐heptose signalling, TRAF2 binding to TIFA requires two short sequence motifs in the C‐terminal tail of TIFA, which are distinct from the TRAF6 binding motif.
Tom Snelling   +4 more
wiley   +1 more source

Information retrieval algorithm of industrial cluster based on vector space

open access: yesOpen Physics, 2019
The current information retrieval research on industrial clusters has low precision, low recall ratio, obvious delay and high energy consumption. Thus, in this paper, a information retrieval algorithm based on vector space for industrial clusters is ...
Li Rongsheng, Hassan Nasruddin
doaj   +1 more source

Conventional Space-Vector Modulation Techniques versus the Single-Phase Modulator for Multilevel Converters [PDF]

open access: yes, 2010
Space-vector modulation is a well-suited technique to be applied to multilevel converters and is an important research focus in the last 25 years. Recently, a single-phase multilevel modulator has been introduced showing its conceptual simplicity and
Carrasco Solís, Juan Manuel   +6 more
core  

From omics to AI—mapping the pathogenic pathways in type 2 diabetes

open access: yesFEBS Letters, EarlyView.
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan   +2 more
wiley   +1 more source

The Canonical Lattice Isomorphism between Topologies Compatible with a Linear Space

open access: yes, 2020
We consider all compatible topologies of an arbitrary finite-dimensional vector space over a non-trivial valuation field whose metric completion is a locally compact space.
Aoyama, Takanobu
core  

Improving Vector Space Word Representations Using Multilingual Correlation

open access: yesConference of the European Chapter of the Association for Computational Linguistics, 2014
The distributional hypothesis of Harris (1954), according to which the meaning of words is evidenced by the contexts they occur in, has motivated several effective techniques for obtaining vector space semantic representations of words using unannotated ...
Manaal Faruqui, Chris Dyer
semanticscholar   +1 more source

Home - About - Disclaimer - Privacy