Results 61 to 70 of about 21,719 (308)

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

open access: yesFEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara   +3 more
wiley   +1 more source

Vectores simbólicos en Matlab

open access: yes, 2019
En este objeto de aprendizaje ha sido usado el bucle for declarar vectores numéricos en Matlab. Para introducir vectores simbólicos en Matlab se ha empleado tanto el bucle for como el bucle while.
Pla Ferrando, Mª Leonor   +2 more
core  

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

Búsqueda de marcadores moleculares para la diferenciación entre Rhodnius prolixus y R. colombiensis vectores de la enfermedad de Chagas

open access: yes, 2002
Este capítulo hace parte del libro: Sistema de información geográfica, sensores remotos y genética poblacional de vectores y parásitos aplicados al control de la Enfermedad de Chagas : memorias del taller, indicando que Rhodnius prolixus stal, es el ...
Montaña, María Fernanda   +3 more
core   +1 more source

Mixed‐class J‐domain protein scaffolds promote expanded aggregate handling and multivalent Hsp70 engagement during functional disaggregase assembly

open access: yesFEBS Letters, EarlyView.
Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley   +1 more source

Las fiebres manchadas y su importancia en Costa Rica

open access: yesActa Médica Costarricense, 2008
La Fiebre Manchada de la Montañas Rocosas es una zoonosis transmitida por garrapatas y causada por una bacteria intracelular obligatoria, la Rickettsia rickettsii.
Laya Hun-Opfer
doaj  

Suma de 3 Vectores

open access: yes, 2016
Ensino Médio::MatemáticaLa animación muestra a través de un gráfico la operación de adición de tres vectores, lo que permite también entender que, en la suma de vectores la propiedad asociativa es válidaTener nociones sobre el concepto de vector, cálculo
Harrison, David M.
core  

Informes 2022 da Rede Galega de Vixilancia de Vectores (ReGaViVec) [PDF]

open access: yes, 2023
[GLG] Os mosquitos e carrachas poden ser vectores de enfermidades se están infectados e, polo tanto, é relevante coñecer a súa presenza. Tendo en conta isto, en Galicia creouse ReGaViVec co obxectivo de coñecer a densidade, distribución espazo-temporal ...

core  

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

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