Results 31 to 40 of about 2,628,537 (340)

Functional characterization of transcriptional enhancers in an Anopheles genetic locus controlling natural resistance to the malaria parasite, Plasmodium falciparum

Epigenetics & Chromatin
Background Anopheles mosquitoes and the malaria parasites they transmit remain a significant global health problem. Most genomic and functional genomic studies of mosquitoes have focused on the protein-coding genome, and comparatively little is known ...
Natalia Marta Zmarlak-Feher, Kathryn S. Taquet, Renée Zakhia, Adrien Pain, Emma Brito-Fravallo, Cameron E. Anderson, Kenneth D. Vernick, Christian Mitri, Michelle M. Riehle   +8 more
doaj   +1 more source

The influence of temperature and humidity on the flight activity of Culicoides imicola both under laboratory and field conditions

Parasites & Vectors, 2019
Background Insight into the factors that regulate the circadian host-seeking flight activity of Culicoides vectors (Diptera: Ceratopogonidae) will be of importance to assess the risk of transmission of Culicoides-borne pathogens.
Gert J. Venter, Solomon N. B. Boikanyo, Chantel J. de Beer   +2 more
doaj   +1 more source

Permanental vectors

Stochastic Processes and their Applications, 2012
A permanental vector is a generalization of a vector with components that are squares of the components of a Gaussian vector, in the sense that the matrix that appears in the Laplace transform of the vector of Gaussian squares is not required to be either symmetric or positive definite.
Kogan, Hana, Marcus, Michael B.
openaire   +2 more sources

The anti‐CRISPR protein AcrIE8.1 inhibits the type I‐E CRISPR‐Cas system by directly binding to the Cascade subunit Cas11

FEBS Letters, EarlyView.
In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley   +1 more source

Nationwide surveillance detects yellow fever and chikungunya viruses in multiple Aedes mosquito species in Nigeria

Parasites & Vectors
Background Since the reemergence of yellow fever in 2017, the Nigeria Centre for Disease Control (NCDC) has been coordinating responses to local outbreaks with the support of the World Health Organization (WHO).
Udoka C. Nwangwu, Harouna Soumare, Judith U. Oguzie, William E. Nwachukwu, Cosmas O. Onwude, Festus A. Dogunro, Mawlouth Diallo, Chukwuebuka K. Ezihe, Nneka O. Agashi, Emelda I. Eloy, Stephen O. Anokwu, Clementina C. Anioke, Linda C. Ikechukwu, Chukwuebuka M. Nwosu, Oscar N. Nwaogo, Ifeoma M. Ngwu, Rose N. Onyeanusi, Angela I. Okoronkwo, Francis U. Orizu, Monica O. Etiki, Esther N. Onuora, Peter C. Okeke, Okechukwu C. Chukwuekezie, Josephine C. Ochu, Anise N. Happi, Sulaiman S. Ibrahim, Adetifa Ifedayo, Chikwe Ihekweazu, Christian T. Happi   +28 more
doaj   +1 more source

Molecular Characterization and Phylogenetic Analysis of Spirometra Tapeworms from Snakes in Hunan Province

Veterinary Sciences, 2022
Sparganosis is a neglected zoonotic parasitic disease that poses huge threats to humans worldwide. Snakes play an important role in sparganosis transmission because they are the most common second intermediate hosts for Spirometra parasites. However, the
Shu-Yu Chen, Teng-Fang Gong, Jun-Lin He, Fen Li, Wen-Chao Li, Li-Xing Xie, Xin-Rui Xie, Yi-Song Liu, Ying-Fang Zhou, Wei Liu   +9 more
doaj   +1 more source

A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins

FEBS Letters, EarlyView.
We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue, Sandrine Picaud, Régine Hepp, Stéphanie Pons, Uwe Maskos, Bertrand Lambolez, Ludovic Tricoire   +6 more
wiley   +1 more source

A Systematic Review of the Natural Virome of Anopheles Mosquitoes

Viruses, 2018
Anopheles mosquitoes are vectors of human malaria, but they also harbor viruses, collectively termed the virome. The Anopheles virome is relatively poorly studied, and the number and function of viruses are unknown. Only the o’nyong-nyong arbovirus (ONNV)
Ferdinand Nanfack Minkeu, Kenneth D. Vernick   +1 more
doaj   +1 more source

Production of germ-free mosquitoes via transient colonisation allows stage-specific investigation of host–microbiota interactions

Nature Communications, 2021
Germ-free mosquitoes generated with current methods exhibit developmental deficits. Here, the authors use genetically modified bacteria to allow complete decolonisation at any developmental stage of Aedes aegypti mosquitoes and show that bacteria support
Ottavia Romoli, Johan Claes Schönbeck, Siegfried Hapfelmeier, Mathilde Gendrin   +3 more
doaj   +1 more source

Frequency of pyrethroid resistance in human head louse treatment: systematic review and meta-analysis

Parasite, 2021
Head lice (Pediculus humanus capitis) are one of the most common insects causing infestations in humans worldwide, and infestation is associated with adverse socio-economic and public health effects. The development of genetic insensitivity (e.g., target
Mohammadi Jalal, Azizi Kourosh, Alipour Hamzeh, Kalantari Mohsen, Bagheri Masoumeh, Shahriari-Namadi Marzieh, Ebrahimi Saeedeh, Moemenbellah-Fard Mohammad D.   +7 more
doaj   +1 more source