Results 151 to 160 of about 345,542 (292)
Novel mechanisms of resistance to vemurafenib in melanoma – V600E B-Raf reversion and switching VEGF-A splice isoform expression [PDF]
Targeting activating mutations in the proto-oncogene B-Raf, in melanoma, has led to increases in progression free survival. Treatment with vemurafenib, which inhibits the most common activating-mutated form of B-Raf (B-RafV600E), eventually results in ...
Bates, DO +4 more
core +1 more source
Two ways VEGF-A builds a vessel
![Graphic][1] Tip cell (green) filopodia follow VEGF-A–expressing astrocytes (red).On [page 1163][2], Gerhardt et al. present a mechanism to explain the function of VEGF in angiogenesis.
openaire +2 more sources
AI–Guided 4D Printing of Carnivorous Plants–Inspired Microneedles for Accelerated Wound Healing
This work presents an artificial intelligence (AI)‐guided 4D‐printed microneedle platform inspired by carnivorous plants for wound healing. A thermo‐responsive shape memory polymer enables body temperature–triggered self‐coiling for autonomous wound closure.
Hyun Lee +21 more
wiley +1 more source
Conductive Hydrogels for Exogenous Sensing and Cell Fate Control
We engineer electrically conductive hydrogels by combining sulfated glycosaminoglycans with semiconducting polymers. These hydrogels bind bioactive proteins, including growth factors, whose release or retention can be modulated by low‐voltage stimulation. The hydrogels are also integrated as 3D channels in organic electrochemical transistors as part of
Teuku Fawzul Akbar +15 more
wiley +1 more source
VEGF-A expression in fat grafts (experimental study)
The study of vascularization of fat implants is focused on the assessment of specific external and/or internal factors affecting its stimulation.The aim.
I. V. Kastyro +8 more
doaj +1 more source
Fabrication, Properties, and Applications of Scaffolds for Bone Tissue Regeneration
This review explores cutting‐edge biomaterials and fabrication techniques for scaffolds in bone tissue regeneration. It conducts a critical comparison of various strategies, meticulously analyzes the key contradictions in the field, and outlines an integrated development path spanning from biomaterial selection to clinical application, while ...
Shangsi Chen, Min Wang
wiley +1 more source
The level of VEGF-A in the lacrimal fluid of diabetic retinopathy
The lacrimal fluid was investigated in 56 people (95 eyes) with type II diabetes, of which 11 (11 eyes) with no signs of diabetic retinopathy and 45 patients (84 eyes) suffering from diabetic retinopathy of varying severity.
Yu. A. Borzilova +4 more
doaj
This review explores the integration of microfluidic technology with organoid systems as an innovative platform for studying menopausea complex multi‐organ condition. By enabling precise simulation of inter‐organ communication and hormone responses, microfluidic organoids offer a physiologically relevant model for investigating menopausal syndrome and ...
Qianyi Zhang +4 more
wiley +1 more source
A Pressure Microsensor Made of Parylene‐C for Use as Medical Implant
A monolithic parylene‐C pressure sensor with gold strain gauges provides 6.2 μV$\mu{\rm V}$·mmHg$\cdot{\rm mmHg}$−1$^{-1}$ sensitivity. The morphology of a sputtered thin film strain sensor is granular/columnar, which results in a high gauge factor of 7.5. Thermal bonding and parylene‐C coating create a hermetic cavity.
Ann‐Kathrin Klein +2 more
wiley +1 more source

