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VEGF: A potential target for hydrocephalus
Cell and Tissue Research, 2014Growth factors are primarily responsible for the genesis, differentiation and proliferation of cells and maintenance of tissues. Given the central role of growth factors in signaling between cells in health and in disease, it is understandable that disruption of growth factor-mediated molecular signaling can cause diverse phenotypic consequences ...
Joon W, Shim +2 more
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VEGF-A is increased in exogenous endophthalmitis
Canadian Journal of Ophthalmology, 2017Exogenous endophthalmitis is an ophthalmologic emergency defined by panocular inflammation. Vascular endothelial growth factor A (VEGF-A) contributes to inflammation by promoting chemotaxis of monocytes and granulocytes and by increasing vascular permeability.
Mark E, Seamone +8 more
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Calreticulin Regulates VEGF-A in Neuroblastoma Cells
Molecular Neurobiology, 2014Calreticulin (CRT) has been previously correlated with the differentiation of neuroblastoma (NB), implying a favorable prognostic factor. Vascular endothelial growth factor (VEGF) has been reported to participate in the behavior of NB. This study investigated the association of CRT and VEGF-A in NB cells.
Wen-Chin, Weng +9 more
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Antiangiogenic VEGF-A in peripheral artery disease
Nature Medicine, 2014Vascular endothelial growth factor A (VEGF-A) is a potent proangiogenic cytokine elevated in patients with peripheral artery disease (PAD). A new study links impaired vascular regrowth in PAD to increased expression of an antiangiogenic splice variant of VEGF-A.
Joshua M, Boucher, Victoria L, Bautch
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Neurological Sciences, 2020
Multiple sclerosis (MS) is among the most common diseases affecting brain and spinal cord. MS progression is characterized by breakdown of blood brain barrier which leads to increased vascular permeability and angiogenesis. Consequently, vascular endothelial growth factor A (VEGF) and its receptors are considered to be important components of MS ...
Ghazaleh Azimi +6 more
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Multiple sclerosis (MS) is among the most common diseases affecting brain and spinal cord. MS progression is characterized by breakdown of blood brain barrier which leads to increased vascular permeability and angiogenesis. Consequently, vascular endothelial growth factor A (VEGF) and its receptors are considered to be important components of MS ...
Ghazaleh Azimi +6 more
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Spatial Expression of VEGF-A in Human Glioma
Journal of Neuro-Oncology, 2002Astrocytoma, especially of high grade, is dependent on neovascularization for its growth and progression. The expression of vascular endothelial growth factor (VEGF-A), an important angiogenesis factor, has been demonstrated in perinecrotic cells in glioblastoma.
Mikael, Johansson +3 more
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OS067. VEGF, a novel stimulator of aldosterone production
Pregnancy Hypertension: An International Journal of Women's Cardiovascular Health, 2012Adrenal aldosterone production depends upon capillary integrity. Inadequately explained by increased renin secretion, aldosterone is high in pregnancy, a proangiogenic state. In preeclampsia, low aldosterone levels coincide with disturbed endothelial integrity due to disrupted VEGF signaling.We hypothesized that the stimulation of adrenal aldosterone ...
C, Gennari-Moser +7 more
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