International Journal on Biological Sciences, 2022 Non-small cell lung cancer (NSCLC) is the leading cause of death by cancer worldwide. Despite developments in therapeutic approaches for the past few decades, the 5-year survival rate of patients with NSCLC remains low.
Yueshui Zhao +15 more
semanticscholar +1 more source
Wound healing induces VEGF expression stimulated by forest honey in palatoplasty Sprague Dawley
Dental Journal, 2023 Background: Cleft palate is a craniofacial disorder with definitive therapy using the V–Y pushback technique palatoplasty, which has the impact of leaving the bone exposed on the palate with long wound healing and a high risk of infection.
Reine Zhafirah +3 more
doaj +1 more source
Benzodiazepine receptor agonist carbacetam modulates the level of vascular endothelial growth factor in the retina of rats with streptozotocin-induced diabetes [PDF]
The Ukrainian Biochemical Journal, 2023 One of the primary mechanisms of retinal neurodegeneration in diabetes mellitus is gamma-aminobutyric acid (GABA) deficiency that makes the use of GABA-benzodiazepine receptor modulators a promising option for the correction of this diabetic complication.
S. V. Ziablitsev +3 more
doaj +1 more source
VEGF guides angiogenic sprouting utilizing endothelial tip cell filopodia [PDF]
, 2003 Vascular endothelial growth factor (VEGF-A) is a major regulator of blood vessel formation and function. it controls several processes in endothelial cells, such as proliferation, survival, and migration, but it is not known how these are coordinately ...
Abramsson, A +10 more
core +2 more sources
Expression of Diverse Angiogenesis Factor in Different Stages of the 4T1 Tumor as a Mouse Model of Triple-Negative Breast Cancer [PDF]
Advanced Pharmaceutical Bulletin, 2020 Purpose: Triple-negative breast cancer (TNBC) is specified by high vascularity and repetitious metastasis. Although several studies have indicated that angiogenesis has an important role in invasive breast cancer, a suitable model of TNBC that can show ...
Saba Malekian +6 more
doaj +1 more source
Engineered microenvironments for synergistic VEGF - integrin signalling during vascularization [PDF]
, 2017 We have engineered polymer-based microenvironments that promote vasculogenesis both in vitro and in vivo through synergistic integrin-growth factor receptor signalling. Poly(ethyl acrylate) (PEA) triggers spontaneous organization of fibronectin (FN) into
Cantini, Marco +9 more
core +2 more sources
Spatiotemporal release of VEGF from biodegradable polylactic-co-glycolic acid microspheres induces angiogenesis in chick chorionic allantoic membrane assay [PDF]
, 2019 The file attached to this record is the author's final peer reviewed version. The Publisher's final version can be found by following the DOI link.While vascular endothelial growth factor (VEGF) is an acknowledged potent pro-angiogenic agent there is a ...
Bullock, Anthony J. +3 more
core +1 more source
VEGF-A in Cardiomyocytes and Heart Diseases
International Journal of Molecular Sciences, 2020 The vascular endothelial growth factor (VEGF), a homodimeric vasoactive glycoprotein, is the key mediator of angiogenesis. Angiogenesis, the formation of new blood vessels, is responsible for a wide variety of physio/pathological processes, including ...
Mariantonia Braile +8 more
semanticscholar +1 more source
Canstatin represses glioma growth by inhibiting formation of VM-like structures
Translational Neuroscience, 2021 Vasculogenic mimicry (VM) is different from classical tumor angiogenesis and does not depend on endothelial cells. VM is closely related to the prognosis of various cancers. Canstatin was first identified as an endogenous angiogenesis inhibitor.
Ma Yuqiang +8 more
doaj +1 more source
VEGF(164)-mediated inflammation is required for pathological, but not physiological, ischemia-induced retinal neovascularization [PDF]
, 2003 Hypoxia-induced VEGF governs both physiological retinal vascular development and pathological retinal neovascularization. In the current paper, the mechanisms of physiological and pathological neovascularization are compared and contrasted.
Adamis, AP +14 more
core +1 more source