International Journal on Biological Sciences, 2022 Non-small cell lung cancer (NSCLC) is the leading cause of death by cancer worldwide. Despite developments in therapeutic approaches for the past few decades, the 5-year survival rate of patients with NSCLC remains low.
Yueshui Zhao +15 more
semanticscholar +1 more source
Wound healing induces VEGF expression stimulated by forest honey in palatoplasty Sprague Dawley
Dental Journal, 2023 Background: Cleft palate is a craniofacial disorder with definitive therapy using the V–Y pushback technique palatoplasty, which has the impact of leaving the bone exposed on the palate with long wound healing and a high risk of infection.
Reine Zhafirah +3 more
doaj +1 more source
Benzodiazepine receptor agonist carbacetam modulates the level of vascular endothelial growth factor in the retina of rats with streptozotocin-induced diabetes [PDF]
The Ukrainian Biochemical Journal, 2023 One of the primary mechanisms of retinal neurodegeneration in diabetes mellitus is gamma-aminobutyric acid (GABA) deficiency that makes the use of GABA-benzodiazepine receptor modulators a promising option for the correction of this diabetic complication.
S. V. Ziablitsev +3 more
doaj +1 more source
Efficacy of tumor-targeting Salmonella typhimurium A1-R in combination with anti-angiogenesis therapy on a pancreatic cancer patient-derived orthotopic xenograft (PDOX) and cell line mouse models. [PDF]
, 2014 The aim of the present study was to examine the efficacy of tumor-targeting Salmonella typhimurium A1-R treatment following anti-vascular endothelial growth factor (VEGF) therapy on VEGF-positive human pancreatic cancer.
Bouvet, Michael +17 more
core +2 more sources
VEGF₁₂₁b and VEGF₁₆₅b are weakly angiogenic isoforms of VEGF-A.
Molecular cancer, 2010 Different isoforms of VEGF-A (mainly VEGF₁₂₁, VEGF₁₆₅ and VEGF189) have been shown to display particular angiogenic properties in the generation of a functional tumor vasculature. Recently, a novel class of VEGF-A isoforms, designated as VEGF(xxx)b, generated through alternative splicing, have been described.
Pio, R. (Rubén) +9 more
openaire +3 more sources
Spatiotemporal release of VEGF from biodegradable polylactic-co-glycolic acid microspheres induces angiogenesis in chick chorionic allantoic membrane assay [PDF]
, 2019 The file attached to this record is the author's final peer reviewed version. The Publisher's final version can be found by following the DOI link.While vascular endothelial growth factor (VEGF) is an acknowledged potent pro-angiogenic agent there is a ...
Bullock, Anthony J. +3 more
core +1 more source
Expression of Diverse Angiogenesis Factor in Different Stages of the 4T1 Tumor as a Mouse Model of Triple-Negative Breast Cancer [PDF]
Advanced Pharmaceutical Bulletin, 2020 Purpose: Triple-negative breast cancer (TNBC) is specified by high vascularity and repetitious metastasis. Although several studies have indicated that angiogenesis has an important role in invasive breast cancer, a suitable model of TNBC that can show ...
Saba Malekian +6 more
doaj +1 more source
VEGF-A, VEGF-C, and VEGF-D in Colorectal Cancer Progression
Neoplasia, 2001 We aimed to assess the relationship of the angiogenic cytokines VEGF-A, VEGF-C, and VEGF-D and their receptors VEGFR-2 and VEGFR-3 in the adenoma-carcinoma sequence and in metastatic spread of colorectal cancer (CRC). mRNA expression levels were measured using semi-quantitative reverse transcription polymerase chain reaction in 70 CRC (35 with paired ...
Mark L. George +6 more
openaire +3 more sources
VEGF guides angiogenic sprouting utilizing endothelial tip cell filopodia [PDF]
, 2003 Vascular endothelial growth factor (VEGF-A) is a major regulator of blood vessel formation and function. it controls several processes in endothelial cells, such as proliferation, survival, and migration, but it is not known how these are coordinately ...
Abramsson, A +10 more
core +2 more sources
VEGF-A in Cardiomyocytes and Heart Diseases
International Journal of Molecular Sciences, 2020 The vascular endothelial growth factor (VEGF), a homodimeric vasoactive glycoprotein, is the key mediator of angiogenesis. Angiogenesis, the formation of new blood vessels, is responsible for a wide variety of physio/pathological processes, including ...
Mariantonia Braile +8 more
semanticscholar +1 more source