Results 21 to 30 of about 313,180 (251)
miR-15a-5p suppresses peritoneal fibrosis induced by peritoneal dialysis via targeting VEGF in rats
Renal Failure, 2020 Aim When peritoneal fibrosis (PF) causes ultrafiltration failure in peritoneal dialysis (PD) patients, PD has to be discontinued. Currently, there is no effective way to relieve PF.
Qianxin He +9 more
doaj +1 more source
RUDN Journal of Medicine, 2022 In the modern paradigm of public health protection, much attention is paid to the health of women in peri- and postmenopause, and a personalized approach prevails.
Irina S. Zhuravleva +4 more
doaj +1 more source
VEGF₁₂₁b and VEGF₁₆₅b are weakly angiogenic isoforms of VEGF-A.
Molecular cancer, 2010 Different isoforms of VEGF-A (mainly VEGF₁₂₁, VEGF₁₆₅ and VEGF189) have been shown to display particular angiogenic properties in the generation of a functional tumor vasculature. Recently, a novel class of VEGF-A isoforms, designated as VEGF(xxx)b, generated through alternative splicing, have been described.
Pio, R. (Rubén) +9 more
openaire +3 more sources
Umbelliprenin Inhibited Angiogenesis and Metastasis of MDA-MB-231 Cell Line through Downregulation of CoCl2 / EGFMediated PI3K / AKT / ERK Signaling [PDF]
Middle East Journal of Cancer, 2022 Background: Breast cancer is known to be one of the most prevalent malignancies in women worldwide. Umbelliprenin (UMB) is a naturally-occurring component derived from plant species, which has shown anticancer properties.
Somayeh Mahmoodi Khatonabadi +7 more
doaj +1 more source
VEGF-Independent Angiogenic Factors: Beyond VEGF/VEGFR2 Signaling [PDF]
Journal of Vascular Research, 2022 Tumors induce angiogenesis to acquire oxygen and nutrition from their adjacent microenvironment. Tumor angiogenesis has been believed to be induced primarily by the secretion of vascular endothelial growth factor-A (VEGF-A) from various tumors.
Ryoji Eguchi +2 more
openaire +2 more sources
NF-κB signaling and crosstalk during carcinogenesis
4 open, 2019 Transcription factors (TFs) are proteins that control the transcription of genetic information from DNA to mRNA by binding to specific DNA sequences either on their own or with other proteins as a complex.
Brücher Björn L.D.M. +2 more
doaj +1 more source
Репродуктивная эндокринология, 2023 Research objectives: to determine the activity of vascular placental growth factors, apoptosis and necrosis of neutrophils in the blood of pregnant women with post-COVID syndrome. Methods and materials. 30 pregnant women (the main group) with SARS-CoV-2,
A.V. Boichuk +3 more
doaj +1 more source
Diabetes, Metabolic Syndrome and Obesity, 2020 Guangrui Chai,1 Shu Liu,2 Hongwei Yang,1 Guoqiang Du,3 Xiaolong Chen1 1Department of Ophthalmology, Shengjing Hospital of China Medical University, Shenyang, Liaoning, People’s Republic of China; 2Department of Geratology, The First Affiliated ...
Chai G, Liu S, Yang H, Du G, Chen X
doaj
Effect of Valeriana Sysimberifolia Extract on VEGF Expression in A549 Cell Line
Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul, 2020 BACKGROUND AND OBJECTIVE: Today, the use of medicinal plants in the treatment of cancer is more important due to its fewer side effects. Vascular endothelial growth factor (VEGF) is one of the most important factors in stimulating angiogenesis and ...
S Chegini, F Tafvizi, H Noorbazargan
doaj
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source