Results 281 to 290 of about 726,516 (374)

Engineering Osteoimmune Responses with Functionalized Orthopedic Implants for Post‐Operative Osteosarcoma Treatment

Advanced Science, EarlyView.
Osteosarcoma is the most common primary bone tumor with limited treatment options and a terrible prognosis. This review provides a comprehensive summary of the recent development of osteoimmunomodulatory implants for post‐operative osteosarcoma treatment, of which the potential utility in evoking durable anti‐osteosarcoma immunity and accelerating bone
Yilong Dong, Lingshuang Wang, Hui Zhang, Menghuan Li, Zhong Luo, Yan Hu, Chunyuan Cai   +6 more
wiley   +1 more source

Astrocyte-vascular interplay in Alzheimer's disease pathology: Novel insights into stage-specific biomarkers and therapeutic targets. [PDF]

Alzheimers Dement
Sheng Z, Chen Y, Chen M, Liang S, Wang J, Chen Y, Li R, Xia B, Gou K, Liu S, Alzheimer's Disease Neuroimaging Initiative, Yu W, Lü Y.   +12 more
europepmc   +1 more source

Characteristics of patients with neovascular age-related macular degeneration who were lost to follow-up and those of patients who continued follow-up for one year after initiating anti-VEGF treatment.

Takaaki Sugisawa (13417212), Fumi Gomi (278082), Yuri Harada (756097), Hiroko Imaizumi (3545441), Shuichiro Aoki (5778473), Akiko Miki (337892), Maya Kishi (15389105), Tomofusa Yamauchi (428670), Daisuke Nagasato (3574904), Yoko Ozawa (418834), Masatoshi Haruta (9532227), Nobuhiro Kato (21526526), Hisashi Matsubara (651891), Tsutomu Yasukawa (6411377), Aki Kato (588812), Hiroto Terasaki (104937), Takao Hirano (13863990), Yasuhiro Iesato (520685), Hiroki Tsujinaka (8783519), Tomoya Murakami (3134658), Yoshinori Mitamura (361411), Makiko Wakuta (14185640), Kazuhiro Kimura (205831), Masahiko Shimura (19832186)   +23 more
openalex   +1 more source

Vascular endothelial growth factor D (VEGF-D) is a ligand for the tyrosine kinases VEGF receptor 2 (Flk1) and VEGF receptor 3 (Flt4).

Proceedings of the National Academy of Sciences of the United States of America, 1998
M. Achen, M. Jeltsch, Eola Kukk, T. Makinen, A. Vitali, A. Wilks, K. Alitalo, S. Stacker   +7 more
semanticscholar   +1 more source

Microglial Fkbp5 Impairs Post‐Stroke Vascular Integrity and Regeneration by Promoting Yap1‐Mediated Glycolysis and Oxidative Phosphorylation

Advanced Science, EarlyView.
A post‐stroke perivascular niche of microglia characterized by low expression of M2 markers and elevated glycolysis, oxidative phosphorylation (OXPHOS), and phagocytic activity is identified, which is termed stroke‐activated vascular‐associated microglia (stroke‐VAM).
Yanan Li, Yanmei Qiu, Yunlei Yang, Yanhao Wei, Haokun Peng, Longhai Zeng, Pengcheng Li, Rentang Bi, Bo Hu   +8 more
wiley   +1 more source

Efficacy of dexamethasone intravitreal implant combined with anti-VEGF drugs in the treatment of diabetic macular edema: a systematic review and meta-analysis. [PDF]

Front Endocrinol (Lausanne)
Chen F, Wang X, Chen M, Xin M, Xian Y.
europepmc   +1 more source

VEGF-induced neuroprotection, neurogenesis, and angiogenesis after focal cerebral ischemia.

Journal of Clinical Investigation, 2003
Yunjuan Sun, K. Jin, Lin Xie, Jocelyn T Childs, X. Mao, A. Logvinova, D. Greenberg   +6 more
semanticscholar   +1 more source

Folic Acid‐Modified Ginger‐Derived Exosome‐Like Nanoparticles Co‐Delivering Sunitinib Suppress Renal Cell Carcinoma via PI3K‐Akt Pathway Inhibition, P‐gp Downregulation, and Macrophage Reprogramming

Advanced Science, EarlyView.
FPD‐GELNs co‐deliver Su and bioactive components. This active‐passive dual‐targeting strategy suppresses the progression of RCC through the following mechanisms: 1) inhibition of the PI3K‐Akt signaling pathway; 2) downregulation of ABCB1/P‐gp to enhance the chemosensitivity of RCC to Su; and 3) reprogramming of macrophages toward M1 polarization and ...
Haoyu Xu, Daixing Hu, Shixue Liu, Lei Yang, Junwu Li, Yuanyuan Bai, Guozhi Zhao, Wei Tang, Li Jiang   +8 more
wiley   +1 more source

LEAP-006: limits and potential of integrating anti-angiogenic agents into first-line multimodal therapy for non-squamous non-small cell lung cancer. [PDF]

J Thorac Dis
Santo V, Garbo E, Pecci F, Aldea M, Ricciuti B, Gariazzo E.   +5 more
europepmc   +1 more source