VEGF-induced neuroprotection, neurogenesis, and angiogenesis after focal cerebral ischemia.
Yunjuan Sun +6 more
semanticscholar +1 more source
KRAS Withdrawal in Cholangiocarcinoma Leads to Immune Infiltration and Tumor Regression
Cholangiocarcinoma (CCA) driven by oncogenic KRAS depends on its continuous activation for tumor maintenance. Using a conditional KRAS model, the authors show that turning off KRAS triggers rapid tumor regression accompanied by immune cell infiltration and cytokine release. The findings uncover a KRAS–senescence–immune signaling axis and highlight KRAS
Youwei Qiao +9 more
wiley +1 more source
Correlation between EGF and VEGF expression levels and the efficacy of radiosurgery in recurrent glioma. [PDF]
Wang J +5 more
europepmc +1 more source
Mechanical Force Storage and Reprogramming Hydrogel for Scarless Repair of Sports Joint Wounds
Inspired by the energy conversion of tendons, the “energy transit station” hydrogel is designed. The hydrogel not only shields stress concentration in sports injuries, but also reprograms energy forms to provide reasonable biomimetic contraction for wounds.
Jiakang Zhang +10 more
wiley +1 more source
Evaluation of the Duration of Good Visual Acuity During Anti-VEGF Therapy for Age-Related Macular Degeneration in Routine Clinical Practice. [PDF]
Gyenes A +13 more
europepmc +1 more source
The fully automated CLIA demonstrates high sensitivity and specificity for plasma Elafin, achieving 88% diagnostic accuracy and an AUC of 0.92 for psoriasis detection in a multicenter cohort. The assay reliably distinguishes psoriasis from other dermatoses, objectively stratifies disease severity, and allows longitudinal monitoring, supporting its ...
Jingkun Yi +8 more
wiley +1 more source
Immunomodulatory Potential of a Composite Amniotic Membrane Hydrogel for Wound Healing: Effects on Macrophage Cytokine Secretion. [PDF]
Wang T, Zhu Z, Hua W, Xue S.
europepmc +1 more source
An age‐adapted therapy pairs δ‐Amyrenone, a CBX7 inhibitor, with an alginate hydrogel (CSAδ) to rescue infarcted elderly hearts. CSAδ disrupts CBX7–ATP7A liquid–liquid phase separation, restores ATP7A trafficking and copper efflux, suppresses cuproptosis, supplies oxygen, scavenges ROS, promotes M2 polarization, supports angiogenesis, and enhances ...
Jun Liu +11 more
wiley +1 more source
AP-1 Is an Initial Convergent Transcriptional Response in Lymphatic Endothelium to VEGF-C or TNFα. [PDF]
Kreft EA, Juśkiewicz ZJ, Isakson BE.
europepmc +1 more source

