Results 341 to 350 of about 726,516 (374)
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VEGF antagonists

Expert Opinion on Biological Therapy, 2001
The majority of cancer have an absolute requirement for angiogenesis, the process by which new blood vessels are formed. The most potent angiogenic cytokine is vascular endothelial growth factor (VEGF) and there has been substantial research into the development of VEGF/VEGF receptor (VEGFR) antagonists.
Hasan, J, Jayson, G
openaire   +3 more sources

Soluble VEGF receptors

Angiogenesis, 1999
The three human VEGF receptors 1-3 mediate biological signals important for new blood vessel formation and lymphangiogenesis. Soluble VEGF receptors contain all the information necessary for high affinity ligand binding and have been used as experimental tools and regulators in several angiogenic in vitro and in vivo models.
C, Hornig, H A, Weich
openaire   +2 more sources

[VEGF, anti-vEGF and diseases].

Bulletin de l'Academie nationale de medecine, 2008
Angiogenesis is a rapidly growing research field. Most of the important vascular growth factors have been identified in the space of a few years, as well as factors responsible for the diferentiation of arteries, veins and lymphatic vessels. The role of angiogenesis in tumor growth, exsudative retinopathies and some inflammatory diseases has been ...
openaire   +1 more source

Current biology of VEGF-B and VEGF-C

Current Opinion in Biotechnology, 1999
Endothelial growth factors and their receptors may provide important therapeutic tools for the treatment of pathological conditions characterised by defective or aberrant angiogenesis. Vascular endothelial growth factor (VEGF) is pivotal for vasculogenesis and for angiogenesis in normal and pathological conditions.
B, Olofsson   +3 more
openaire   +2 more sources

The biology of VEGF and its receptors

Nature Medicine, 2003
N. Ferrara, H. Gerber, J. Lecouter
semanticscholar   +1 more source

VEGF receptor signalling ? in control of vascular function

Nature reviews. Molecular cell biology, 2006
A. Olsson   +3 more
semanticscholar   +1 more source

Vascular endothelial growth factor (VEGF) and its receptors

The FASEB Journal, 1999
G. Neufeld   +3 more
semanticscholar   +1 more source

VEGF and ALS

Neuroscience Research, 2008
In amyotrophic lateral sclerosis (ALS), an adult-onset progressive degeneration of motor neurons occurring as sporadic and familial disease, there is emerging evidence for and against the role of vascular endothelial growth factor (VEGF), an endothelial cell mitogen crucial for angiogenesis, in its etiopathogenesis.
openaire   +2 more sources

Abnormal blood vessel development and lethality in embryos lacking a single VEGF allele

Nature, 1996
P. Carmeliet   +15 more
semanticscholar   +1 more source

Heterozygous embryonic lethality induced by targeted inactivation of the VEGF gene

Nature, 1996
N. Ferrara   +8 more
semanticscholar   +1 more source

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