Results 271 to 280 of about 2,468,898 (371)

Engineering antibodies with cancer‐associated binding sites

open access: yesBMEMat, EarlyView.
This review describes antibodies that perform direct/indirect roles in cancer treatment by binding to effective targets and discusses how antibodies kill tumors and modulate tumor microenvironment through these targets. The classification of expression systems for antibody production is summarized to guide appropriate selection based on different ...
Yinqi Tian   +4 more
wiley   +1 more source

Vascular endothelial growth factor A: friend or foe in the pathogenesis of HIV and SARS-CoV-2 infections? [PDF]

open access: yesFront Cell Infect Microbiol
van der Mescht MA   +3 more
europepmc   +1 more source

Antibacterial hydrogel: The sniper of chronic wounds

open access: yesBMEMat, EarlyView.
The treatment of chronic wounds has always been an important challenge in the medical field. We focus on hydrogels not only because they provide a moist healing environment but also because compared with traditional dressings, they can effectively prevent and treat infections, reduce wound pain and scar formation.
Shengtai Bian   +6 more
wiley   +1 more source

Unveiling the complexity of cellular senescence in cancers: From mechanism to therapeutic opportunities

open access: yesBMEMat, EarlyView.
This review highlights the complex roles of cellular senescence in cancer progression and suppression, discusses the mechanisms and regulatory pathways involved, and evaluates the efficacy of the “One‐Two punch” sequential treatment approach while addressing emerging challenges in this novel therapeutic strategy.
Qiuming Pan   +12 more
wiley   +1 more source

From death to birth: how osteocyte death promotes osteoclast formation. [PDF]

open access: yesFront Immunol
Zhao W   +7 more
europepmc   +1 more source

Aminated graphene nanosheet stimulates the maturation of hiPSCs‐derived cardiomyocytes in vitro and enhances their survival in vivo

open access: yesBMEMat, EarlyView.
Aminated graphene (G‐NH2) niche matrix plays a pivotal role in precisely manipulating cardiac differentiation and maturation of hiPSCs. The molecular mechanism underlying cardiomyocyte maturation is closely linked to the PDGF‐β signaling pathway. Cardiomyocytes derived from the G‐NH2 matrix exhibit enhanced activity and functionality in vivo.
Yin Xu   +6 more
wiley   +1 more source

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