Results 271 to 280 of about 2,650,230 (376)

VEGF; VEGF receptor 2 (KDR/Flk-1; VEGFR-2) [PDF]

Science-Business eXchange, 2010
openaire   +1 more source

The KDM6B/SLC10A2 Axis Suppresses MDSCs Recruitment via ERK/AP‐1 Signaling in Colorectal Cancer

Advanced Science, EarlyView.
In wild‐type intestinal epithelial cells, KDM6B demethylates SLC10A2 to promote its expression, after which SLC10A2 suppresses ERK phosphorylation, inhibiting AP‐1 (Fos/Jun) transcription and chemokine production. In KDM6B‐deficient intestinal epithelial cells, SLC10A2 methylation increases, and its expression decreases.
Zhibo Hu, Jing Xun, Bin Liu, Xiaolin Jiang, Yingdi Han, Huichao Yang, Qi Gao, Ruifang Gao, Aimin Zhang, Xueliang Wu, Dapeng Zhang, Dihua Li, Tian Li, Shimin Yang, Ximo Wang, Xiangyang Yu, Qi Zhang   +16 more
wiley   +1 more source

Bradykinin reduces wound healing in human umbilical vein endothelial cells via downregulation of vascular endothelial growth factor A. [PDF]

J Inflamm (Lond)
Dimitrova N, Gierke A, Möhrle R, Nemeth J, Brunner C, Hoffmann TK, Greve J, Hahn J, Lochbaum R.   +8 more
europepmc   +1 more source

The role of VEGF receptor inhibitors in preventing cerebral radiation necrosis: a retrospective cohort study

, 2020
Iyad Alnahhas, Appaji Rayi, Joshua D. Palmer, Raju R. Raval, Edmund Folefac, Shirley Ong, Pierre Giglio, Vinay K. Puduvalli   +7 more
openalex   +2 more sources

Antiemesis Corticosteroids Potentiate Checkpoint Blockade Efficacy by Normalizing the Immune Microenvironment in Metastatic Murine Breast Cancer

Advanced Science, EarlyView.
Corticosteroids improve the efficacy of immune checkpoint blockade therapy in metastatic murine breast cancer. By normalizing the tumor immune microenvironment, corticosteroids reduce immunosuppressive signals, restore T‐cell function, and promote antitumor immune responses, resulting in enhanced tumor control.
John D. Martin, Koji Nagaoka, Myrofora Panagi, Akihiro Hosoi, Fotios Mpkeris, Pengwen Chen, Thahomina T. Khan, Margaret R. Martin, Changbo Sun, Chrysovalantis Voutouri, Maria Louca, Panagiotis Papageorgis, Akira Sumiyoshi, Nobuhiro Nitta, Kazuyoshi Takeda, Ichio Aoki, Kazunori Kataoka, Triantafyllos Stylianopoulos, Kazuhiro Kakimi, Horacio Cabral   +19 more
wiley   +1 more source

AdipoRon promotes angiogenesis in B-cell leukemia by modulating pro-angiogenic factors through AdipoR1. [PDF]

Mol Biol Rep
Mallardo M, Russo R, Daniele A, Chambery A, Nigro E.   +4 more
europepmc   +1 more source

Opinion: Inhibition of Blood-Brain Barrier Repair as a Mechanism in HIV-1 Disease. [PDF]

, 2017
Maubert, Monique E., Nonnemacher, Michael R., Wigdahl, Brian   +2 more
core   +2 more sources

CXC chemokine receptor 4 (CXCR4; NPY3R); VEGF; VEGF receptor 1 (FLT1; VEGFR-1) [PDF]

Science-Business eXchange, 2011
openaire   +1 more source

Mutual Exclusion Analysis Shows that DUSP9 Negatively Regulates PD‐L1 Expression and Acts as a Target to Enhance Anti‐PD‐1 Efficacy

Advanced Science, EarlyView.
A mutually exclusive screening system is established to identify negative regulators of highly plastic genes. Dual specificity phosphatase (DUSP9) is a novel negative regulatory molecule of PD‐L1 by dephosphorylating STAT3, and acts as a target molecule in combination with PD‐1 antibody for tumor immunotherapy and a new clinical biomarker for ...
Yuzhe Hu, Ling Tang, Zheng Kuang, Danyi Huang, Ting Li, Gaofei Yin, Yingyu Chen, Wei Guo, Wenling Han, Pingzhang Wang   +9 more
wiley   +1 more source

Vascular endothelial generating factor pathway in ovarian cancer. [PDF]

J Ovarian Res
Zhao Y, Chen Q, Li J, Liu F, Dong K, Han F.   +5 more
europepmc   +1 more source