Results 281 to 290 of about 2,468,898 (371)

Pre‐folding purification procedures for inclusion body‐derived non‐tagged cationic recombinant proteins with multiple disulfide bonds for efficient refolding

Biotechnology Progress, EarlyView.
Abstract The production of disulfide‐containing recombinant proteins often requires refolding of inclusion bodies before purification. A pre‐refolding purification step is crucial for effective refolding because impurities in the inclusion bodies interfere with refolding and subsequent purification.
Shuichiro Kimura, Wataru Yamamoto, Ai Miyamoto, Koreyoshi Imamura, Junichiro Futami   +4 more
wiley   +1 more source

von Willebrand disease and angiodysplasia: a wider view of pathogenesis in pursuit of therapy. [PDF]

Haematologica
Crossette-Thambiah C, Randi AM, Laffan M.   +2 more
europepmc   +1 more source

Endothelin receptor antagonists (ERAs) can potentially be used as therapeutic drugs to reduce hypertension caused by small molecule tyrosine kinase inhibitors (TKIs). [PDF]

Front Pharmacol
He Q, Lin J, Mo C, Li G, Lu J, Sun Q, Cao L, Gan H, Sun Q, Yao J, Lian S, Wang W.   +11 more
europepmc   +1 more source

Adenosine diphosphate stimulates VEGF-independent choroidal endothelial cell proliferation: A potential escape from anti-VEGF therapy. [PDF]

Proc Natl Acad Sci U S A
Biswas N, Mori T, Ragava Chetty Nagaraj NK, Xin H, Diemer T, Li P, Su Y, Piermarocchi C, Ferrara N.   +8 more
europepmc   +1 more source

Highly efficient naked DNA delivery of a soluble form of VEGF receptor suppressed the growth of murine renal cell carcinoma.

, 2003
Hiroshi Yazawa, Takaya Murakami, Tim Back, Yasuhiro Suzuki, Lynnete Shorts, Robert H. Wiltrout, Morihiro Watanabe   +6 more
openalex   +2 more sources

Cuproplasia and cuproptosis, two sides of the coin

Cancer Communications, EarlyView.
Abstract Copper is an essential micronutrient in the human body, mainly acting as a crucial cofactor required for a wide range of physiological processes across nearly all cell types. Recent advances revealed that tumor cells seize copper to fulfill their rapid proliferation, metastasis, immune evasion, and so on by reprogramming the copper regulatory ...
Kaizhong Lu, Chandra Sugiarto Wijaya, Qinghua Yao, Hongchuan Jin, Lifeng Feng   +4 more
wiley   +1 more source

The Landscape of Vascular Endothelial Growth Factor Inhibition in Retinal Diseases. [PDF]

Invest Ophthalmol Vis Sci
Lin JB, Apte RS.
europepmc   +1 more source

Glycometabolic Regulation of Angiogenesis: Mechanisms and Therapeutic Strategies. [PDF]

Int J Mol Sci
Yao Z, Li J, Yu J, Cheng Y, Fang C, Chen X, Chen X, Wang Y, Gao D, Lin F.   +9 more
europepmc   +1 more source

Copper in cancer: friend or foe? Metabolism, dysregulation, and therapeutic opportunities

Cancer Communications, EarlyView.
Abstract Copper, one of the essential nutrients for the human body, acts as an electron relay in multiple pathways due to its redox properties. Both deficiencies and excesses of copper lead to cellular fragility. Therefore, it can manifest pro‐ and anti‐cancer properties in tumors. Therefore, it is crucial to clarify the copper activity within the cell.
Dan Shan, Jinling Song, Yuqing Ren, Yuyuan Zhang, Yuhao Ba, Peng Luo, Quan Cheng, Hui Xu, Siyuan Weng, Anning Zuo, Shutong Liu, Xinwei Han, Jinhai Deng, Zaoqu Liu   +13 more
wiley   +1 more source

Atherosclerosis: A Comprehensive Review of Molecular Factors and Mechanisms. [PDF]

Int J Mol Sci
Tasouli-Drakou V, Ogurek I, Shaikh T, Ringor M, DiCaro MV, Lei K.   +5 more
europepmc   +1 more source