Results 191 to 200 of about 24,477,013 (226)

Sulfonamides a Promising Hit for Cancer Therapy Through VEGFR-2 Inhibition. [PDF]

Biomedicines
Charissopoulos E, Pontiki E.
europepmc   +1 more source

Novel pyrazole-oxadiazole-chalcone/oxime hybrids as dual EGFR/VEGFR-2 inhibitors with promising anticancer potential: a comprehensive cytotoxicity evaluation, mechanistic insights and SAR analysis. [PDF]

Mol Divers
Alshazly O, Abdel-Aziz M, Abuo-Rahma GEA, Mohamed MFA.   +3 more
europepmc   +1 more source

Design, synthesis, and anticancer evaluation of novel pyrazole-thiophene hybrid derivatives as multitarget inhibitors of wild EGFR, mutant (T790M) EGFR, and VEGFR-2. [PDF]

RSC Adv
Sallam MN, Al-Karmalawy AA, Abbass EM, Hawas SS, El-Naggar AM, Hassan AMA.   +5 more
europepmc   +1 more source

Design, synthesis, and characterization of novel 5-ethylsulfonyl-indazole-3-carboxamides as dual VEGFR-2 and EGFR inhibitors: apoptotic antiproliferative and immunomodulatory evaluations. [PDF]

RSC Adv
Al-Wahaibi LH, Othman SA, Abou-Zied HA, Bräse S, Youssif BGM, Rabea SM.   +5 more
europepmc   +1 more source

Synthesis, antiproliferative evaluation and <i>in silico</i> studies of new quinazoline derivatives as VEGFR-2 inhibitors. [PDF]

Future Med Chem
Abdelsalam Ouf AM, Marzouk AA, Shaykoon MSA, Celik I, Bakhotmah DA, Mansour AA, Alamoudi MK, Alfayomy AM, El-Zahabi MA.   +8 more
europepmc   +1 more source

In silico discovery of alkaloids as VEGFR-2 inhibitors with favorable toxicity profiles: insights from molecular dynamics and MM/GBSA. [PDF]

In Silico Pharmacol
da Silva Maués N, Farias NB, do Socorro Barros Brasil D, da Costa RA.   +3 more
europepmc   +1 more source

Anti-breast cancer potential of thieno-pyrimidine derivatives as VEGFR-2 inhibitors. [PDF]

Future Med Chem
Alsfouk AA, Al Ward MMS, Al-Qadhi MA, El-Metwally SA, Yousef RG, Elkaeed EB, Husein DZ, Amin FG, Elkady H, Metwaly AM, Eissa IH.   +10 more
europepmc   +1 more source

Discovery of thieno[2,3-<i>d</i>]pyrimidine-based dual Aurora B/VEGFR-2 inhibitors with potent anticancer activity: molecular docking, mechanistic studies, and <i>in vivo</i> validation in a breast cancer model. [PDF]

RSC Adv
El-Shafey HW, Hamdi A, Elnagar MR, Gebril SM, Haikal A, El-Azab AS, Brogi S, Al-Suwaidan IA, Abdel-Aziz AA.   +8 more
europepmc   +1 more source

Comparison between conventional, grinding, and microwave synthesis of methylpyrazoles as VEGFR-2/HSP90 dual inhibitors. [PDF]

Future Med Chem
Husseiny EM, Abdelnaby RM, Altwaijry N, Saleh A, Anwer KE.   +4 more
europepmc   +1 more source

Synthesis of thiazoloquinolinone derivatives: molecular docking, MD simulation, and pharmacological evaluation as VEGFR-2 inhibitors. [PDF]

BMC Chem
Amiri Z, Bayat M, Gheidari D.
europepmc   +1 more source