Results 61 to 70 of about 1,766,181 (306)

Nonlinear dynamics modeling and simulation of two-wheeled self-balancing vehicle

International Journal of Advanced Robotic Systems, 2016
Two-wheeled self-balancing vehicle system is a kind of naturally unstable underactuated system with high-rank unstable multivariable strongly coupling complicated dynamic nonlinear property.
Yunping Liu, Xijie Huang, Tianmiao Wang, Yonghong Zhang, Xianying Li   +4 more
doaj   +1 more source

The influence of vehicle dynamics on the time-dependent resonances of a bridge

Advances in Bridge Engineering, 2023
In bridge structural health monitoring, the response of the bridge while the vehicle is on the bridge, is called a vehicle-bridge interaction (VBI) response.
Neda Mostafa, Dario Di Maio, Richard Loendersloot, Tiedo Tinga   +3 more
doaj   +1 more source

An ant colony system for responsive dynamic vehicle routing [PDF]

European Journal of Operational Research, 2015
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire   +1 more source

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

FEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty, Kelsi R. Hall, Zachary D. Tillett, Liam S. Turk, James S. Davies, Michael J. Currie, Hamish G. Brown, Sepideh Valimehr, Peter D. Mace, Andrew E. Whitten, Santosh Panjikar, Eric Hanssen, Rachel A. North, Renwick C.J. Dobson   +13 more
wiley   +1 more source

Unraveling 4‐Phenylbutyrate's Therapeutic Role in SLC6A1 Disorders: Pharmacochaperoning Over HDAC Inhibition

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw, Karishma Randhave, Ekta Anand, Ziang (Debbie) Song, Wangzhen Shen, Jing‐Qiong Kang   +5 more
wiley   +1 more source

Augmenting and Assaying Nav1.1 Protein Quantity for Dravet Syndrome Therapy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Dravet Syndrome (DS) is a developmental and epileptic encephalopathy predominantly caused by heterozygous loss‐of‐function variants in SCN1A, which encodes Nav1.1. Conserved upstream open reading frames (uORFs) in SCN1A were validated to regulate translation in reporter assays, demonstrating the therapeutic viability of increasing Nav1.1 from ...
Aiswarya Saravanan, Jordan Safran, Anna Loughman, Grace Lin, Shivanshi Vaid, Dana Allababidi, Peter M. Tessier, Louis T. Dang   +7 more
wiley   +1 more source

A Q‐Learning Algorithm to Solve the Two‐Player Zero‐Sum Game Problem for Nonlinear Systems

International Journal of Adaptive Control and Signal Processing, Volume 39, Issue 3, Page 566-581, March 2025.
A Q‐learning algorithm to solve the two‐player zero‐sum game problem for nonlinear systems. ABSTRACT This paper deals with the two‐player zero‐sum game problem, which is a bounded L2$$ {L}_2 $$‐gain robust control problem. Finding an analytical solution to the complex Hamilton‐Jacobi‐Issacs (HJI) equation is a challenging task.
Afreen Islam, Anthony Siming Chen, Guido Herrmann   +2 more
wiley   +1 more source

Air‐Pressure–Actuated Vibroacoustic Metamaterial With Tunable Bandgap: Design, Modeling, and Characterization

Advanced Engineering Materials, EarlyView.
This article presents the design, modeling, and characterization of air‐pressure–actuated programmable vibroacoustic metamaterials (PVAMM). The study focuses on leveraging air pressure to dynamically tune resonance frequencies for effective noise attenuation.
William Kaal, Michael M. Becker, Sarah C. L. Fischer   +2 more
wiley   +1 more source

A framework for wheel profile wear prediction of high-speed trains considering tread modification

Friction
Tread modification has gained significant attention in recent years as a means to address the issue of wheel hollow wear. The wear resulting from tread modification can alter the wheel profile, thereby impacting the wheel–rail contact relationship and ...
Yuchen Xie, Maoru Chi, Wubin Cai, Shulin Liang, Yixiao Li, Yabo Zhou, Peng Wang   +6 more
doaj   +1 more source

Multibody dynamics modeling of electromagnetic direct-drive vehicle robot driver

International Journal of Advanced Robotic Systems, 2017
Collaborative dynamics modeling of flexible multibody and rigid multibody for an electromagnetic direct-drive vehicle robot driver is proposed in the article. First, spatial dynamic equations of the direct-drive vehicle robot driver are obtained based on
Gang Chen, Weigong Zhang, Bing Yu
doaj   +1 more source