Results 141 to 150 of about 399,751 (297)

Vibration‐Mediated Recovery of Irradiated Osteocytes and Their Regulatory Role in Breast Cancer Bone Metastasis

open access: yesAdvanced Healthcare Materials, EarlyView.
Radiotherapy damages bone and disrupts osteocyte function, yet mechanically mediated protection remains largely unexplored. This study demonstrates that low‐magnitude, high‐frequency (LMHF) vibration mitigates irradiated osteocyte apoptosis, restores their ability to regulate breast cancer extravasation, and acts synergistically with radiotherapy to ...
Xin Song   +7 more
wiley   +1 more source

DEATH PRODUCED BY TYING THE ADRENAL VEINS [PDF]

open access: bronze, 1919
Frank A. Hartman, William E. Blatz
openalex   +1 more source

Translational Considerations for Injectable Biomaterials and Bioscaffolds to Repair and Regenerate Brain Tissue

open access: yesAdvanced Healthcare Materials, EarlyView.
The repair and regeneration of brain tissue faces both biological and technical challenges. Injectable bioscaffolds offer new opportunities to stimulate tissue regrowth in the brain by recruiting neural stem cells. Here, the translational issues are reviewed that need to be address to advance this promising new therapeutic approach from the bench to ...
Michel Modo, Alena Kisel
wiley   +1 more source

Human Endometrial Extracellular Matrix Hydrogel Facilitated Endometrial Mesenchymal Stem Cells for Endometrial Regeneration

open access: yesAdvanced Healthcare Materials, EarlyView.
Adequate thickness of the uterine lining is crucial for women with thin or damaged endometrium to achieve pregnancies. Endometrial mesenchymal stem cells (eMSC) can facilitate the cyclical repair and regeneration of the human endometrium. In this study, the human endometrium derived extracellular matrix hydrogel supports the growth of eMSC promoting ...
Jingwen Xu   +9 more
wiley   +1 more source

Using High‐Throughput Screening to Identify Crosslinking Peptides That Control Cell‐Mediated Matrix Degradation

open access: yesAdvanced Healthcare Materials, EarlyView.
Protease‐degradable hydrogels mimic dynamic cell‐matrix interactions, but controlling hydrogel degradation is a challenge. We screen libraries of peptides to identify sequences that are primarily degraded by membrane‐localized proteases. Crosslinking hydrogels with these peptides enables cell to spread and migrate while reducing matrix degradation ...
Yingjie Wu   +3 more
wiley   +1 more source

3D‐Printed Multidimensional Bionic Mg‐MC/PLGA Composite for Tailored Repair of Segmental Long Bone Defects

open access: yesAdvanced Healthcare Materials, EarlyView.
This study develops 3D‐printed Mg‐MC/PLGA scaffolds with varying Mg concentrations (0–20%). The 5% Mg scaffold shows optimal cytocompatibility, osteogenic activity in vitro, and significantly enhances bone regeneration in rabbits, improving bone volume and mechanical strength.
Shihang Liu   +9 more
wiley   +1 more source

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