Results 61 to 70 of about 1,218,893 (387)
FEBS Letters, EarlyView.B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro +2 more
wiley +1 more source
Molecular Oncology, EarlyView.Combining melting curve analysis enhances the multiplexing capability of digital PCR. Here, we developed a 14‐plex assay to simultaneously measure single nucleotide mutations and amplifications of KRAS and GNAS, which are common driver genes in pancreatic cancer precursors. This assay accurately quantified variant allele frequencies in clinical samples
Junko Tanaka +10 more
wiley +1 more source
Cosmetics, 2023 The correction of leg telangiectasias is one of the most frequently performed interventions in the Western world. While sclerotherapy remains the gold standard of treatment, several studies have shown comparable efficacy and, in some situations, an even ...
Kristine Heidemeyer +5 more
doaj +1 more source
Inhibitor of DNA binding‐1 is a key regulator of cancer cell vasculogenic mimicry
Molecular Oncology, EarlyView.Elevated expression of transcriptional regulator inhibitor of DNA binding 1 (ID1) promoted cancer cell‐mediated vasculogenic mimicry (VM) through regulation of pro‐angiogenic and pro‐cancerous genes (e.g. VE‐cadherin (CDH5), TIE2, MMP9, DKK1). Higher ID1 expression also increased metastases to the lung and the liver.
Emma J. Thompson +11 more
wiley +1 more source
Hypertension, 2016 See related article, pp 418–426 Veins lack luster when it comes to hypertension research. Compared with the scientist working on arterial branches, heart, or kidney, the vein researcher commonly feels like being at the bottom of the cardiovascular food chain.
Kristine Chobanyan-Jürgens, Jens Jordan
openaire +3 more sources
Distally-based free anterolateral thigh flap with a modified vena comitans
Archives of Plastic Surgery, 2019 With the recent development in microsurgery, the use of a perforator flap has been widely implemented. If the length of the ALT flap pedicle is insufficient despite adequate preoperative planning, pedicle length extension is necessary.
Chan-Su Kang, Tae-Gon Kim
doaj +1 more source
A comparative study between visual, near infrared and infrared images for the detection of veins for intravenous cannulation [PDF]
, 2015 The process of identification and locating of veins plays an important role to reduce health care cost and suffering of patients during intravenous cannulation.
Al-Habaibeh, A, Asrar, M, Houda, MR
core
Molecular Oncology, EarlyView.Loss of primary cilia in endothelial cells promotes EndMT and vascular abnormalities in the ovarian tumor microenvironment through EphA2 activation. Using human samples, in vitro models, and endothelial‐specific Kif3a‐knockout mice, we show that primary cilia loss drives the acquisition of cancer‐associated fibroblast‐like phenotypes, thereby ...
Jin Gu Cho +11 more
wiley +1 more source
The perfect crime? : CCSVI not leaving a trace in MS [PDF]
, 2011 Background: Multiple sclerosis (MS) is a chronic, inflammatory demyelinating disease of the central nervous system, believed to be triggered by an autoimmune reaction to myelin.
Bechmann, Ingo Jürgen +6 more
core +3 more sources
Molecular Oncology, EarlyView.Carcinoma‐associated fibroblasts (CAFs) in tumors influence cancer progression. We identified endoglin (ENG) as a key factor in TGF‐β signaling in myofibroblastic CAFs (myCAFs), linked to poor breast cancer outcomes. Inhibiting ENG on myCAFs suppressed the TGF‐β‐Smad2/3 pathway, reducing primary tumor growth and metastasis.
Shoki Okubo +11 more
wiley +1 more source