Results 71 to 80 of about 1,254,542 (388)

Naked cuticle is essential for Drosophila wing development beyond Wingless signaling

FEBS Open Bio, EarlyView.
Naked cuticle (Nkd), a Wnt signaling inhibitor, assumes extensive roles in Drosophila wing development. Overexpressing Nkd causes smaller, crumpled wings, while also perturbing multiple signaling pathways and developmental genes. A specific region (R1S) is critical for Nkd's function as a signaling integrator, offering new insights for studying its ...
Rui Wang, Ping Wang
wiley   +1 more source

Carbonate alteration of ophiolitic rocks in the Arabian–Nubian Shield of Egypt: sources and compositions of the carbonating fluid and implications for the formation of Au deposits [PDF]

, 2016
Ultramafic portions of ophiolitic fragments in the Arabian–Nubian Shield (ANS) show pervasive carbonate alteration forming various degrees of carbonated serpentinites and listvenitic rocks.
Azer, Mokhles K., Boskabadi, Arman, Boyce, Adrian, Broman, Curt, Cooper, Matthew J., Majka, Jaroslaw, Mohamed, Fathy H., Pitcairn, Iain K., Stern, Robert J., Teagle, Damon A.H.   +9 more
core   +2 more sources

DDX3X induces mesenchymal transition of endothelial cells by disrupting BMPR2 signaling

FEBS Open Bio, EarlyView.
Elevated DDX3X expression led to downregulation of BMPR2, a key regulator of endothelial homeostasis and function. Our co‐immunoprecipitation assays further demonstrated a molecular interaction between DDX3X and BMPR2. Notably, DDX3X promoted lysosomal degradation of BMPR2, thereby impairing its downstream signaling and facilitating endothelial‐to ...
Yu Zhang, Jing Wang, De‐Hui Qian, Yang‐Fan Lv, Tian‐Le Cheng, Da‐Peng Wang, Jing Zhang, Ye Fan   +7 more
wiley   +1 more source

Observation and analysis of in situ carbonaceous matter in Nakhla: Part I [PDF]

, 2006
New analyses of indigenous secondary material in the martian meteorite Nakhla reveal amorphous carbon-rich veins and dendrites. The texture and chemistry of this material resembles that of biogenically altered sub-ocean basaltic ...
Clemett, S. J., Gibson, E. K., Jr., McKay, D. S., Pillinger, C. T., Rice, T., Robert, F., Thomas-Kerpta, K. L., VanLeer, B., Verchovsky, A. B., Wentworth, S. J., Wright, I. P.   +10 more
core   +2 more sources

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

Successful Hemodialysis Using an Iatrogenic Graft-to-Vein Fistula in Failing Arteriovenous Graft with Chronic Thrombotic Occlusion

대한영상의학회지, 2017
An iatrogenic graft-to-vein fistula that develops between a vascular access graft and an adjacent vein is a rare but significant complication. We report a case of an arteriovenous hemodialysis graft (AVG) with an iatrogenic graft-to-vein fistula and a
Yeo Ryang Kang, Jae Hyun Kwon
doaj   +1 more source

Preliminary Implementation of the Next Generation Cannulation Simulator [PDF]

, 2019
© 2019 IEEE. Personal use of this material is permitted. Permission from IEEE must be obtained for all other uses, in any current or future media, including reprinting/republishing this material for advertising or promotional purposes, creating new ...
Abdallah, Omrane, Abducarim, Aiman, Alinier, Guillaume, Alsalemi, Abdullah, Amira, Abbes, Bensaali, Faycal, Fawzy Hassan, Ibrahim, Hssain, Ali Ait, Khurshid, Uzair, Mahmoud, Abdulrahman, Mahmud, Sakib, Mohamed, Elshaikh   +11 more
core   +2 more sources

Impact of APOE ε4 Genotype Load on Cognitive Function and Lipid Metabolism in Patients With Cerebral Small Vessel Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Apolipoprotein ε4 (APOE ε4) is a potent genetic risk factor for Alzheimer's disease (AD). However, its role in cerebral small vessel disease (CSVD) remains unclear. Given the clinical and pathological similarities between CSVD and AD, this study aimed to investigate the associations of APOE ε4 gene dosage with cognitive function and
Tingru Jin, Haocheng Yang, Feng Liu, Sihao Lin, Junru Hu, Jian Wang, Yulan Gou   +6 more
wiley   +1 more source

Gestação e varizes de membros inferiores: prevalência e fatores de risco Pregnancy and lower limb varicose veins: prevalence and risk factors

Jornal Vascular Brasileiro, 2010
Contexto: Durante e após a gestação, as varizes dos membros inferiores têm aspectos peculiares, tais como o seu aparecimento, a precocidade de seu desenvolvimento, a intensidade e, no puerpério, a rapidez com que regridem. Esses aspectos têm influenciado
Newton de Barros Junior, Maria Del Carmen Janeiro Perez, Jorge Eduardo de Amorim, Fausto Miranda Junior   +3 more
doaj   +1 more source

Genesis of self-organized zebra textures in burial dolomites : displacive veins, induced stress, and dolomitization [PDF]

, 2006
The dolomite veins making up rhythmites common in burial dolomites are not cement infillings of supposed cavities, as in the prevailing view, but are instead displacive veins, veins that pushed aside the host dolostone as they grew.
Canals, A., Fletcher, R.C., Merino, E.
core   +4 more sources