Results 71 to 80 of about 1,580,311 (297)

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Wind Tunnel Investigation of Wake Characteristics of a Wing with Winglets

Engineering Proceedings
Aircraft performance metrics such as range and endurance are highly dependent on induced and vortex drag. There is a close relationship between wake structure and aerodynamic performance.
Stanimir Penchev, Hristian Panayotov, Martin Zikyamov   +2 more
doaj   +1 more source

A statistical search for detection of possible rigid blocks in the Arabia-Eurasia oblique collision zone (Iran)

Journal of Geodetic Science, 2013
In this research an investigation has been done to determine the possible more rigid blocks in the region of Iran based on the Euler pole estimations.
Nozari M., Voosoghi B., Rastbood A.
doaj   +1 more source

On Optimisation Approach to Velocity Field Determination in Image Processing Problems

Известия Иркутского государственного университета: Серия "Математика", 2018
The problem of determining the velocity field is investigated. This problem is considered by many authors in various formulations. The most well-known statement of the problem is proposed with the use of a concept of optical flow of constant distribution
P.V. Bazhanov, E.D. Kotina
doaj   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Reprocessing of three-decade GNSS observations: millimeter-level nonlinear terrestrial reference frame, global velocity field and plate motion model refinement

Geo-spatial Information Science
The Terrestrial Reference Frame (TRF) is essential for solid Earth research, including geodesy and geodynamics, providing a unified spatiotemporal datum.
Hu Wang, Yingying Ren, Ming Chen, Yamin Dang, Jing Jiao, Qiang Yang, Jiexian Wang   +6 more
doaj   +1 more source

Correlation between ore particle flow pattern and velocity field through multiple drawpoints under the influence of a flexible barrier

Open Geosciences, 2019
By means of similar tests, the stope room is scaled and the process of multiple-drawpoint ore drawing under the influence of a flexible barrier is simulated by the marking particle method.
Qin Shikang, Chen Qingfa, Chen Qinglin, Zhao Fuyu   +3 more
doaj   +1 more source

Slip-velocity of large neutrally-buoyant particles in turbulent flows

, 2012
We discuss possible definitions for a stochastic slip velocity that describes the relative motion between large particles and a turbulent flow. This definition is necessary because the slip velocity used in the standard drag model fails when particle ...
Bellani G, Clift R, E A Variano, Efron B, Elghobashi S, G Bellani, Saarenrinne P, Squires K D, Tsinober A   +8 more
core   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

A robust method for fitting peculiar velocity field models

, 2000
We present a new method for fitting peculiar velocity models to complete flux limited magnitude-redshifts catalogues, using the luminosity function of the sources as a distance indicator.The method is characterised by its robustness.
Bertschinger, Bertschinger, Bicknell, Bigot, Branchini, Choloniewski, Colless, Courteau, da Costa, Dale, Davis, Dekel, Dekel, Dekel, Efron, Ekholm, Fisher, Fliche, Freudling, Giovanelli, Giovanelli, Giovanelli, Han, Hendry, Hendry, Hudson, Landy, Lauer, Lynden-Bell, Lynden-Bell, Martin A. Hendry, Mathewson, Newsam, Nusser, Rauzy, Rauzy, Rauzy, Rauzy, Riess, Sandage, Sigad, Strauss, Stéphane Rauzy, Teerikorpi, Teerikorpi, Theureau, Theureau, Theureau, Tonry, Triay, Triay, Wegner, Willick, Willick, Willick, Willick, Willick, Willick, Willick, Willick   +59 more
core   +3 more sources