Results 71 to 80 of about 1,534,656 (293)
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
The aim of the research is to find the maximum velocity possessed by the molecules (Maxwell velocity distribution) of the solvation event of lithium hexafluorophosphate salt interacting with ethylene carbonate (EC) solvent.
Hubertus Ngaderman +1 more
doaj +1 more source
Anomalous Bloch oscillations in one dimensional parity-breaking periodic potentials
We investigate the dynamics of a wave packet in a parity-breaking one-dimensional periodic potential slowly varied in time and perturbed by a linear potential. Parity is broken by considering an asymmetric double well per unit cell.
Modugno, Michele, Pettini, Giulio
core +1 more source
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Potential Vorticity and the Quasigeostrophic and Semigeostrophic MesoscaleVertical Velocity
Support for this research has come from the Spanish Ministerio de Ciencia y Tecnología Grant REN2002-01343 and the program Ramón y Cajal 2001, as well as the UK National Environmental Research Council (Grant GR3/11899)
Viúdez, Álvaro, Dritschel, David G.
openaire +3 more sources
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Modeling the Terminal Velocity of Rising Electrocharged Microbubbles
The generation of electrocharged microbubbles is very important for several separation processes (e.g., water treatment, paper industry, and mineral processing). However, their rising terminal velocities are not fully understood.
Roberto Pérez-Garibay +3 more
doaj +1 more source
The Prevalence of Gas Outflows in Type 2 AGNs. II. 3D Biconical Outflow Models
We present 3D models of biconical outflows combined with a thin dust plane for investigating the physical properties of the ionized gas outflows and their effect on the observed gas kinematics in type 2 active galactic nuclei (AGNs). Using a set of input
Bae, Hyun-Jin, Woo, Jong-Hak
core +1 more source
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Geofluids and up-to-date display of activization of the Ingul megablock of the Ukrainian Shield
High degree of geological-geophysical studies of crustal processes combined with analysis of 3D P-velocity model of the mantle under the Ukrainian Shield and its southern surrounding up to the depth of 2500 km allowed to correlate manifestations of ...
V. I. Starostenko +3 more
doaj +1 more source

