Results 61 to 70 of about 1,534,656 (293)

Close encounters involving RAVE stars beyond the 47 Tucanae tidal radius

, 2016
The most accurate 6D phase-space information from the Radial Velocity Experiment (RAVE) was used to integrate the orbits of 105 stars around the galactic globular cluster 47 Tucanae, to look for close encounters between them in the past, with a minimum ...
Fernández-Trincado, J. G., Moreno, E., Palmer, M., Pichardo, B., Reylé, C., Robin, A. C., Valenzuela, O., Vieira, K.   +7 more
core   +4 more sources

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Age variation of motor nerve conduction study in healthy adults: A physiological reference

APIK Journal of Internal Medicine, 2023
Background: Nerve conduction study (NCS) is the simple noninvasive technique to assess the functional status of peripheral nerves. Physiological variables such as age, sex, anthropometric indices influence the functional status of peripheral nerves ...
Sunil Kumar Jena, Manoranjan Acharya
doaj   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

Unsteady Electroosmotic Flow of Jeffrey Fluid in a Circular Microchannel under the Combined Action of Vertical Magnetic Field, External Electric Field, and Pressure at High Zeta Potential

Advances in Mathematical Physics, 2022
The unsteady electroosmotic flow (EOF) for one kind of linear viscoelastic fluid, which is Jeffrey type fluid, is investigated under the common impact of vertical magnetic field, external electric field, and pressure at high Zeta potential in a circular ...
Meirong Ren, Tiange Zhang, Jifeng Cui, Xiaogang Chen, Bixia Wu   +4 more
doaj   +1 more source

AAA+ protein unfoldases—the Moirai of the proteome

FEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

Influence of substrate potential shape on the dynamics of a sliding lubricant chain

, 2013
We investigate the frictional sliding of an incommensurate chain of interacting particles confined in between two nonlinear on-site substrate potential profiles in relative motion. We focus here on the class of Remoissenet-Peyrard parametrized potentials
Manini, Nicola, Vanossi, Andrea, Woulaché, Rosalie Laure   +2 more
core   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

CLASSICAL MOLECULAR DYNAMICS (MD) SIMULATION OF SALT AND SOLVENT SOLVATION EVENTS IN LITHIUM ION BATTERIES TO DETERMINE ENERGY FLUCTUATIONS

Jurnal Neutrino: Jurnal Fisika dan Aplikasinya
This study looks at how salt and solvent mix, as shown by the final positions of particles in a simulation. The simulation uses Lennard-Jones parameters and runs in a closed system with fixed energy. The goal is to see if the particles follow the Maxwell
Hubertus Ngaderman, Ego Srivajawaty Sinaga, Benny Abraham Bungasalu   +2 more
doaj   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source