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Sofosbuvir and Velpatasvir for HCV Genotype 2 and 3 Infection
BACKGROUND: In phase 2 trials, treatment with the combination of the nucleotide polymerase inhibitor sofosbuvir and the NS5A inhibitor velpatasvir resulted in high rates of sustained virologic response in patients chronically infected with hepatitis C ...
Graham R Foster +2 more
exaly +2 more sources
Clinical Pharmacokinetics, 2018
The pharmacokinetics and safety of velpatasvir, a potent pangenotypic hepatitis C virus NS5A inhibitor, were evaluated in two hepatic impairment studies: a phase I study in hepatitis C virus-uninfected subjects and a phase III study (ASTRAL-4) in hepatitis C virus-infected patients.In the phase I study, subjects with moderate or severe hepatic ...
Erik Mogalian +11 more
openaire +2 more sources
The pharmacokinetics and safety of velpatasvir, a potent pangenotypic hepatitis C virus NS5A inhibitor, were evaluated in two hepatic impairment studies: a phase I study in hepatitis C virus-uninfected subjects and a phase III study (ASTRAL-4) in hepatitis C virus-infected patients.In the phase I study, subjects with moderate or severe hepatic ...
Erik Mogalian +11 more
openaire +2 more sources
Sofosbuvir/velpatasvir/Sofosbuvir/velpatasvir/voxilaprevir
Reactions Weekly, 2023openaire +1 more source

