Results 151 to 160 of about 3,654 (190)
Some of the next articles are maybe not open access.

Sofosbuvir and Velpatasvir for HCV Genotype 2 and 3 Infection

open access: yesNew England Journal of Medicine, 2015
BACKGROUND: In phase 2 trials, treatment with the combination of the nucleotide polymerase inhibitor sofosbuvir and the NS5A inhibitor velpatasvir resulted in high rates of sustained virologic response in patients chronically infected with hepatitis C ...
Graham R Foster   +2 more
exaly   +2 more sources

Pharmacokinetics and Safety of Velpatasvir and Sofosbuvir/Velpatasvir in Subjects with Hepatic Impairment

Clinical Pharmacokinetics, 2018
The pharmacokinetics and safety of velpatasvir, a potent pangenotypic hepatitis C virus NS5A inhibitor, were evaluated in two hepatic impairment studies: a phase I study in hepatitis C virus-uninfected subjects and a phase III study (ASTRAL-4) in hepatitis C virus-infected patients.In the phase I study, subjects with moderate or severe hepatic ...
Erik Mogalian   +11 more
openaire   +2 more sources

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