Results 91 to 100 of about 210,415 (275)

Cervical Inlet Patches in R‐CPD: An Unrecognized Predictor of Treatment Failure

The Laryngoscope, EarlyView.
This retrospective cohort study identified cervical inlet patches (CIP) in 19.8% of patients undergoing cricopharyngeal botulinum toxin injection for R‐CPD. CIP presence and increasing age independently predicted failure to sustain a long‐term treatment response, suggesting that CIP may be an underrecognized factor in R‐CPD treatment durability ...
Andrew Geoffrey Tritter, Nabeeha Hasan, Jered Wilson   +2 more
wiley   +1 more source

Quantitative and qualitative analysis of Bitis arietans total RNA isolated from lyophilized venom, TRIzol-treated venom and venom gland.

, 2016
(A) Lyophilized (VLYO, blue line), TRIzol-treated (VTRZ, red line) venom and (B) venom gland tissue. The y-axis is an arbitrary unit of fluorescence, and the x-axis shows the nucleotide length of the RNA.
John P. Dunbar (2825906), Kam-Yin D. Leung (2825900), Paul D. Rowley (144846), Nicholas R. Casewell (360450), Robert A. Harrison (144845), Gareth Whiteley (2825894), Fiona J. Newberry (2825903), Simon C. Wagstaff (144848), Rhiannon A. E. Logan (2825897)   +8 more
core   +1 more source

Analysis of Carbohydrates and Glycoconjugates by Matrix‐Assisted Laser Desorption/Ionization Mass Spectrometry: An Update for 2023–2024

Mass Spectrometry Reviews, EarlyView.
ABSTRACT The use of MALDI mass spectrometry for the analysis of carbohydrates and glycoconjugates is a well‐established technique and this comprehensive review is the twelfth update of the original article published in 1999 and brings coverage of the literature to the end of 2024.
David J. Harvey
wiley   +1 more source

Comparative proteomic analysis of differential expression induced by noradrenergic innervation in venom gland and accessory gland of Bothrops jararaca snake.

, 2013
Análise proteômica das glândulas de veneno e acessória durante o ciclo de produção de veneno e a influência da inervação noradrenérgica na síntese de proteínas foi verificada.
Luna, Milene Schmidt do Amaral e, Milene Schmidt do Amaral e Luna   +1 more
core   +1 more source

Navigating the Complexity: A Comprehensive Review of GSK‐3 Inhibition in Regenerative Medicine

Medicinal Research Reviews, EarlyView.
ABSTRACT Glycogen synthase kinase‐3 (GSK‐3) is a central regulator of numerous cellular signaling pathways, with critical roles in metabolism, proliferation, differentiation, and tissue regeneration. This review explores the multifaceted effects of pharmacological GSK‐3 inhibition across multiple body districts, focusing on its highly context‐dependent
Davide Schiroli, Alessia Merra, Chiara Marraccini, Lucia Merolle, Graziella Pellegrini, Eleonora Maurizi   +5 more
wiley   +1 more source

Advancing Therapies for Mycobacterial Diseases: From Small Molecules to Host‐Directed Strategies

Medicinal Research Reviews, EarlyView.
ABSTRACT The global burden of multidrug‐resistant tuberculosis (MDR‐TB) and the rising incidence of nontuberculous mycobacterial (NTM) infections highlight the urgent need for innovative therapeutic strategies. Current treatments are prolonged, toxic, and increasingly compromised by resistance and limited diagnostic capacity.
Tânia Silva, Alessandra Aiello, Tonino Alonzi, M. Alice Carvalho, Vladimir Finger, Delia Goletti, Sven Hoffner, Yousra Kherabi, Jan Korabecny, Julia Kulczyńska, Agnieszka Kyzioł, Alicia Lacoma, Filomena Martins, Zorica Nanovic, Sepideh Hosseiniporgham, Martina Hrast Rambaher, Leonardo Antonio Sechi, Daria Smalchuk, Grażyna Stochel, Lydia Tabernero, Nancy L. Tateosian, Violeta Valcheva, Anamarija Zega, Mafalda Sarraguça   +23 more
wiley   +1 more source

Integrative multi-omics analysis reveals the contribution of neoVTX genes to venom diversity of Synanceia verrucosa

BMC Genomics
Background Animal venom systems are considered as valuable model for investigating the molecular mechanisms underlying phenotypic evolution. Stonefish are the most venomous and dangerous fish because of severe human envenomation and occasionally ...
Zhiwei Zhang, Qian Li, Hao Li, Shichao Wei, Wen Yu, Zhaojie Peng, Fuwen Wei, Wenliang Zhou   +7 more
doaj   +1 more source

Dynamic Rearrangement in Snake Venom Gland Proteome: Insights into Bothrops jararaca Intraspecific Venom Variation

, 2016
We carried out an analysis of the venom gland proteome of Bothrops jararaca taking into account two distinct phases of its ontogenetic development (i.e., newborn and adult) and the marked sexual dimorphism recently reported on its venom proteome ...
Débora Andrade-Silva (2869070), Solange M. T. Serrano (2118343), Isabella Fukushima (3113661), André Zelanis (1743517), César Augusto-de-Oliveira (3113667), Eduardo S. Kitano (1743514), Tarcísio Liberato (3113670), Daniel R. Stuginski (3113664)   +7 more
core   +1 more source

Relational knowing as method and practice

People and Nature, EarlyView.
Abstract This paper seeks to contribute to (re)building the capacity for embodied, place‐based relational knowing, transforming how we know and thus what we know. What is known, or sought to be known, is relations. How we know these relations is by already being in it: breathing, sensing, moving, listening, responding, affecting and being affected ...
Katie Moon
wiley   +1 more source

Differential FGFR1 copy number status displays unique tumour immune microenvironment in triple‐negative breast cancer

The Journal of Pathology, EarlyView.
Abstract Fibroblast growth factor receptor 1 (FGFR1) amplification, a significant cancer alteration with both prognostic and therapeutic relevance, lacks a standardized definition. The relationship between FGFR1 copy number (CN) variations and tumour microenvironment (TME) characteristics also remains poorly understood.
Yike Gao, Fei Yao, Junyi Pang, Tianlin Sun, Changbin Zhu, Shafei Wu, Zhiyong Liang   +6 more
wiley   +1 more source