Results 191 to 200 of about 14,053 (243)

Convergent Total Synthesis of 16β‐Hydroxylpseudobufarenogin

open access: yesAngewandte Chemie, Volume 138, Issue 23, 1 June 2026.
We present a novel convergent strategy that integrates Pd/Ag‐promoted Suzuki–Miyaura coupling with Ir‐catalyzed radical‐relay cyclization, enabling the first total synthesis of 16β‐hydroxylpseudobufarenogin. This approach is broadly applicable to the total synthesis of various oxygenated bufadienolides by simply modifying the fragment structures ...
Wataru Shigematsu   +3 more
wiley   +2 more sources

A Survey for Deep Reinforcement Learning Based Network Intrusion Detection

open access: yesApplied AI Letters, Volume 7, Issue 2, June 2026.
This paper surveys deep reinforcement learning (DRL) for network intrusion detection, evaluating model efficiency, minority attack detection, and dataset imbalance. Findings show DRL achieves state‐of‐the‐art results on public datasets, sometimes surpassing traditional deep learning.
Wanrong Yang   +3 more
wiley   +1 more source

Microstructural Evidence for Early Childhood Stress in a Community in Transition at Hisban, Jordan

open access: yesAmerican Journal of Biological Anthropology, Volume 190, Issue 2, June 2026.
ABSTRACT Objectives Identification of stress across infancy and childhood can reflect maternal and environmental influences on early life health. In the 19th century community of Hisban, many infants died before 2 years of age with evidence of metabolic disease, including rickets, that likely ties with maternal health.
Kristina Cockerille   +4 more
wiley   +1 more source

Intraspecific venom variation in the medically important puff adder ( Bitis arietans ): comparative venom gland transcriptomics, in vitro venom activity and immunological recognition by antivenom

open access: yes
Dawson CA   +12 more
europepmc   +1 more source

INTRODUCTION: SCENES OF CLOSE READING

open access: yes
German Life and Letters, Volume 79, Issue 3, Page 281-297, July 2026.
Carolin Duttlinger   +2 more
wiley   +1 more source

Snake Venom Gland Organoids [PDF]

open access: yesCell, 2020
Wnt dependency and Lgr5 expression define multiple mammalian epithelial stem cell types. Under defined growth factor conditions, such adult stem cells (ASCs) grow as 3D organoids that recapitulate essential features of the pertinent epithelium. Here, we establish long-term expanding venom gland organoids from several snake species.
Merijn A G De Bakker   +2 more
exaly   +11 more sources
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Venom glands in scatophagid fish

Toxicon, 1970
Venom glands have been demonstrated in scatophagid fishes for the first time. Six specimens of Scatophagus argus, from 62 mm to 296 mm in standard length, possessed a pair of venom glands accommodated in paired antero-lateral grooves in each fin spine. The venom glands of the larger specimens were shorter than those of the smaller fishes. In Selenotoca
Cameron A.M., Endean R.
openaire   +5 more sources

Unmasking venom gland transcriptomes in reptile venoms

Analytical Biochemistry, 2002
While structural studies of reptile venom toxins can be achieved using lyophilized venom samples, until now the cloning of precursor cDNAs required sacrifice of the specimen for dissection of the venom glands. Here we describe a simple and rapid technique that unmasks venom protein mRNAs present in lyophilized venom samples. To illustrate the technique
Chen, Tianbao   +6 more
openaire   +3 more sources

Combined snake venomics and venom gland transcriptomic analysis of Bothropoides pauloensis

Journal of Proteomics, 2012
Unraveling the repertoire of venom toxins of Bothropoides pauloensis was assessed by snake venomics and venom gland transcriptomic surveys. Both approaches yielded converging overall figures, pointing to metalloproteinases (~37%), PLA(2)s (26-32%), and vasoactive (bradykinin-potentiating) peptides (12-17%) as the major toxin classes.
Renata Santos Rodrigues   +2 more
exaly   +3 more sources

Viperid venom glands with defective venom production. Morphological study

Toxicon, 2013
The venom of viperid snakes is collected monthly at Butantan Institute for research purposes and production of antivenoms. Here we describe histological and ultrastructural changes on Crotalus durissus terrificus and Bothrops sp. venom glands with defective venom production.
Karina Cristina, Giannotti   +6 more
openaire   +2 more sources

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