Results 131 to 140 of about 88,797 (311)

‘I, Me, Myself’: Selfhood and Melancholy in the Journals of Gertrude Savile (1697–1758)

Journal for Eighteenth-Century Studies, EarlyView.
Abstract This article examines the journals of Gertrude Savile from 1727 in light of recent scholarship on early modern and eighteenth‐century melancholy. The concept had myriad associations with medicine, physiology, the imagination, and feeling, but questions remain about how melancholy during this period was considered by those outside the narrow ...
Daniel Beaumont
wiley   +1 more source

The Toxin Diversity, Cytotoxicity, and Enzymatic Activity of Cape Cobra (Naja nivea) Venom

Toxins
“True” cobras (genus Naja) are among the venomous snakes most frequently involved in snakebite accidents in Africa and Asia. The Cape cobra (Naja nivea) is one of the African cobras of highest medical importance, but much remains to be learned about its ...
Tim Lüddecke, Ignazio Avella, Maik Damm, Lennart Schulte, Johanna Eichberg, Kornelia Hardes, Susanne Schiffmann, Marina Henke, Thomas Timm, Günter Lochnit, Andreas Vilcinskas   +10 more
doaj   +1 more source

Efficacy of House Dust Mite Immunotherapy in Chinese Allergic Rhinitis Patients With Diverse Sensitization Patterns: A Multicenter Study (COVER Study)

Allergy, EarlyView.
This prospective multicenter study corroborates the efficacy of AIT with the native HDM allergen extract in Chinese AR patients with diverse HDM sensitization patterns. HDM sensitization pattern affects the efficacy of AIT, with patients sensitized to both major and minor allergens of HDM showing improved outcomes with HDM SCIT.
Qingxiu Xu, Xuan Yuan, Wang Liao, Hao Chen, Qing Jiang, Lin Yang, Jin Liu, Le Li, Nan Huang, Wenjing Li, Yaqi Yang, Dongxia Ma, Jun Bai, Zhihai Xie, Rongfei Zhu   +14 more
wiley   +1 more source

Effects of Oligoelements Se, Zn, and Mn plus Lachesis Muta Venom in Experimental Scleroderma [PDF]

, 2013
Ernesto Crescenti, Vanina A. Medina, Lorena Sambuco, Graciela Cremaschi, Ana Marı́a Genaro, G. Cricco, G. Martín, Eduardo Valli, Diego J. Martinel Lamas, Juan Carlos Perazzo, Elena Rivera, R. Bergoc   +11 more
openalex   +1 more source

Thaumatin‐Like Proteins in Molecular Allergy Diagnostics: Uncommon, Co‐Sensitized, and Clinically Inconspicuous? Insights From an Italian Cohort

Allergy, EarlyView.
This study assessed the prevalence, quantitative IgE levels, co‐sensitization patterns, and clinical significance of IgE reactivity to two TLPs—Act d 2 (kiwi) and Mal d 2 (apple)—in a large Italian allergic cohort. Thaumatin‐like protein (TLP) sensitization was uncommon (1.9%) and usually clinically silent when isolated.
Enrico Scala, Damiano Abeni, Mauro Giani, Valeria Villella, Elisabetta Caprini, Ignazio Brusca, Lorenzo Cecchi, Danilo Villalta, Riccardo Asero   +8 more
wiley   +1 more source

Prolonged IL‐33 Exposure Switches the Secreted Mast Cell Cytokine Profile From Pro‐Inflammatory to Pro‐Tolerant

Allergy, EarlyView.
This study investigates the effect of IL‐33 and Hymenoptera venom on mast cell cytokine profiles under venom immunotherapy (VIT)‐like conditions. Our in vitro model of VIT‐like mast cell stimulation demonstrates a modulatory effect of IL‐33 on the secreted mast cell cytokine profile.
Andrea R. Teufelberger, Carolin Költgen, Magda Babina, Peter Wolf   +3 more
wiley   +1 more source

Pioneering Comparative Proteomic and Enzymatic Profiling of Amazonian Scorpion Venoms Enables the Isolation of Their First α-Ktx, Metalloprotease, and Phospholipase A₂

Toxins
Scorpionism is a growing public health concern in Brazil, with the Amazon region presenting the highest mortality rates but remaining understudied, especially regarding local scorpion venoms composition.
Karla C. F. Bordon, Gabrielle C. Santos, Jonas G. Martins, Gisele A. Wiezel, Fernanda G. Amorim, Thomas Crasset, Damien Redureau, Loïc Quinton, Rudi E. L. Procópio, Eliane C. Arantes   +9 more
doaj   +1 more source

Molecular IgE Reactivity Profiling With Micro‐Arrayed Allergens Reveals Distinct Interregional Patterns of Sensitization and a Hypoallergenic Region in Türkiye

Allergy, EarlyView.
A prospective, systematic and cross‐sectional population study was performed involving 1000 adult subjects from five centers representing different climatic areas of Türkiye (Turkey). Molecular IgE profiling demonstrated substantial interregional variation and identified a hypoallergenic region in the easternmost area with a continental climate.
Alp Kazancioglu, Huey‐Jy Huang, Sengul Aksakal, Ismet Bulut, Maria‐Roxana Buzan, Kuan‐Wei Chen, Monica Daniela Cotarcă, Alexandra Dubovets, Pia Gattinger, Okan Gulbahar, Ali Fuat Kalyoncu, Alexander Karaulov, Evgenii Kozlov, Carmen Panaitescu, Thomas Schlederer, Daria Trifonova, Mikhail Tulaev, Murat Turk, Susanne Vrtala, Milena Weber, Lauriana‐Eunice Zbîrcea, Bulent Enis Sekerel, Rudolf Valenta   +22 more
wiley   +1 more source

A Straightforward Algorithm for Diagnosing Hymenoptera Venom Allergy and Identifying the Relevant Venom for Immunotherapy

Allergy, EarlyView.
Conventional tests, such as specific IgE (sIgE) or intradermal testing (IDT), are usually sufficient. Combining both tests increases sensitivity, while additional tests, like the basophil activation test (BAT), provide no further benefit for the majority of patients.
Lisa Arzt‐Gradwohl, Eva Schadelbauer, Urban Čerpes, Gudrun Pregartner, Sereina Annik Herzog, Elisabeth Jungwirth, Karin Laipold, Barbara Binder, Gunter J. Sturm   +8 more
wiley   +1 more source

Evaluation of the geographical utility of Eastern Russell’s viper ( Daboia siamensis ) antivenom from Thailand and an assessment of its protective effects against venom-induced nephrotoxicity [PDF]

, 2019
Janeyuth Chaisakul, Nattapon Sookprasert, Robert A. Harrison, Narongsak Chaiyabutr, Lawan Chanhome, Nicholas R. Casewell   +5 more
openalex   +1 more source