Results 61 to 70 of about 89,990 (337)

Venomics and Peptidomics of Palearctic Vipers: A Clade-Wide Analysis of Seven Taxa of the Genera Vipera, Montivipera, Macrovipera, and Daboia across Türkiye

bioRxiv
Snake venom variations are a crucial factor to understand the consequences of snakebite envenoming worldwide and therefore it’s important to know about toxin composition alterations between taxa.
Maik Damm, M. Karış, D. Petráš, A. Nalbantsoy, B. Göçmen, R. Süssmuth   +5 more
semanticscholar   +1 more source

Strategies in ‘snake venomics’ aiming at an integrative view of compositional, functional, and immunological characteristics of venoms

Journal of Venomous Animals and Toxins including Tropical Diseases, 2017
This work offers a general overview on the evolving strategies for the proteomic analysis of snake venoms, and discusses how these may be combined through diverse experimental approaches with the goal of achieving a more comprehensive knowledge on the ...
B. Lomonte, J. Calvete
semanticscholar   +1 more source

An Economic Dilemma between Molecular Weapon Systems May Explain an Arachno-Atypical Venom in Wasp Spiders (Argiope bruennichi)

Biomolecules, 2020
Spiders use venom to subdue their prey, but little is known about the diversity of venoms in different spider families. Given the limited data available for orb-weaver spiders (Araneidae), we selected the wasp spider Argiope bruennichi for detailed ...
Tim Lüddecke, Björn M. von Reumont, Frank Förster, André Billion, Thomas Timm, Günter Lochnit, Andreas Vilcinskas, Sarah Lemke   +7 more
doaj   +1 more source

Snakebite envenoming. [PDF]

, 2017
Snakebite envenoming is a neglected tropical disease that kills >100,000 people and maims >400,000 people every year. Impoverished populations living in the rural tropics are particularly vulnerable; snakebite envenoming perpetuates the cycle of poverty.
Calvete, Juan J, Gutiérrez, José María, Habib, Abdulrazaq G, Harrison, Robert, Warrell, David A, Williams, David J   +5 more
core   +3 more sources

Repurposing cancer drugs, batimastat and marimastat, to inhibit the activity of a group I metalloprotease from the venom of the Western Diamondback rattlesnake, Crotalus atrox [PDF]

, 2020
Snakebite envenomation causes over 140,000 deaths every year predominantly in developing countries. As a result, it is one of the most lethal neglected tropical diseases.
Bicknell, Andrew B., Lakshminarayanan, Karthik, Layfield, Harry J., Mehmi, Amita, Patel, Ketan, Ravishankar, Divyashree, Salim, Anika, Sonavane, Medha, Trim, Steven A., Vaiyapuri, Rajendran, Vaiyapuri, Sakthivel, Vallance, Thomas M., Williams, Harry F.   +12 more
core   +1 more source

A Venomics approach coupled to high-throughput toxin production strategies identifies the first venom-derived melanocortin receptor agonists.

Journal of Medicinal Chemistry, 2020
Animal venoms are rich in hundreds of toxins with extraordinary biological activities. Their exploitation is difficult due to their complexity and the small quantities of venom available from most venomous species.
S. Reynaud, J. Ciolek, M. Degueldre, N. Saez, A. Sequeira, Y. Duhoo, J. Brás, H. Meudal, Miguel Cabo Diez, Victoria Fernández Pedrosa, Marion Verdenaud, Julia Boeri, Oscar Henrique Pereira Ramos, F. Ducancel, Margot Vanden Driessche, R. Fourmy, Aude Violette, G. Upert, G. Mourier, A. Beck‐Sickinger, K. Mörl, C. Landon, C. Fontes, Rebeca Miñambres Herráiz, Ricardo C. Rodríguez de la Vega, S. Peigneur, J. Tytgat, L. Quinton, E. De Pauw, R. Vincentelli, D. Servent, N. Gilles   +31 more
semanticscholar   +1 more source

Toxins from scratch? Diverse, multimodal gene origins in the predatory robber fly Dasypogon diadema indicate a dynamic venom evolution in dipteran insects

, 2019
Venoms and the toxins they contain represent molecular adaptations that have evolved on numerous occasions throughout the animal kingdom. However, the processes that shape venom protein evolution are poorly understood because of the scarcity of whole ...
Bokelmann, L., Drukewitz, S., Undheim, E., von Reumont, B.   +3 more
core   +1 more source

Durable Physically Mixed Microporous and Mesoporous MOFs/Nanofiber Aerogel 3D Composites for Effective Toxic Gas Capture and Organophosphonate Detoxification

Advanced Functional Materials, EarlyView.
Ultralight 3D nanofibrous aerogels embedded with metal‐organic frameworks effectively capture and neutralize toxic gases and organophosphonates. Incorporating mesoporous UiO‐66‐NH2 and HKUST‐1 into PAN/PVP fibers enables high MOF loading while maintaining mechanical strength and structural stability.
Mai O. Abdelmigeed, Muhammed Ziauddin Ahmad Ebrahim, John J. Mahle, Brandon B. Blount, Gregory W. Peterson, Saad A. Khan, Gregory N. Parsons   +6 more
wiley   +1 more source

Metal–Organic Frameworks for Gaseous Pollutant Management: From Capture to Neutralization and Reutilization

Advanced Functional Materials, EarlyView.
This review maps how MOFs can manage hazardous gases by combining adsorption, neutralization, and reutilization, enabling sustainable air‐pollution control. Covering chemical warfare agent simulants, SO2, NOx, NH3, H2S, and volatile organic compounds, it highlights structure‐guided strategies that boost selectivity, water tolerance, and cycling ...
Yuanmeng Tian, Zeyu Tao, Kaikai Ma, Xiaoliang Wang, Bo Yu, Yiu Wan Yip, Zhijie Chen, Jin Shang, Bin Fei   +8 more
wiley   +1 more source

From birth to bite: the evolutionary ecology of India's medically most important snake venoms

BMC Biology
Background Snake venoms can exhibit remarkable inter- and intraspecific variation. While diverse ecological and environmental factors are theorised to explain this variation, only a handful of studies have attempted to unravel their precise roles.
R. R. Senji Laxme, Suyog Khochare, Siddharth Bhatia, Gerard Martin, Kartik Sunagar   +4 more
doaj   +1 more source