Results 61 to 70 of about 985 (235)

Effect of age class on the survivorship and spatial movement patterns of headstarted Texas horned lizards soft‐released into an urban population

The Journal of Wildlife Management, EarlyView.
When compared to resident lizards of the corresponding age class, juvenile headstarted Texas horned lizards soft‐released into an urban population exhibited more favorable responses to short‐term translocation objectives (i.e., daily movement rates, home range sizes, and survival rates) than did conspecifics headstarted to the adult age class ...
Forrest P. Nielsen, Raymond W. Moody, Rebecca J. Snyder, Cameron R. Forehand, Katharine A. Marske, Hayley Lanier, Jessa L. Watters, Cameron D. Siler   +7 more
wiley   +1 more source

Venom-derived peptides for breaking through the glass ceiling of drug development

Frontiers in Chemistry
Venoms are complex mixtures produced by animals and consist of hundreds of components including small molecules, peptides, and enzymes selected for effectiveness and efficacy over millions of years of evolution.
Lou Freuville, Chloé Matthys, Loïc Quinton, Jean-Pierre Gillet   +3 more
doaj   +1 more source

Biotechnological Trends in Spider and Scorpion Antivenom Development

Toxins, 2016
Spiders and scorpions are notorious for their fearful dispositions and their ability to inject venom into prey and predators, causing symptoms such as necrosis, paralysis, and excruciating pain.
Andreas Hougaard Laustsen, Mireia Solà, Emma Christine Jappe, Saioa Oscoz, Line Præst Lauridsen, Mikael Engmark   +5 more
doaj   +1 more source

Navigating the Complexity: A Comprehensive Review of GSK‐3 Inhibition in Regenerative Medicine

Medicinal Research Reviews, EarlyView.
ABSTRACT Glycogen synthase kinase‐3 (GSK‐3) is a central regulator of numerous cellular signaling pathways, with critical roles in metabolism, proliferation, differentiation, and tissue regeneration. This review explores the multifaceted effects of pharmacological GSK‐3 inhibition across multiple body districts, focusing on its highly context‐dependent
Davide Schiroli, Alessia Merra, Chiara Marraccini, Lucia Merolle, Graziella Pellegrini, Eleonora Maurizi   +5 more
wiley   +1 more source

Advancing Therapies for Mycobacterial Diseases: From Small Molecules to Host‐Directed Strategies

Medicinal Research Reviews, EarlyView.
ABSTRACT The global burden of multidrug‐resistant tuberculosis (MDR‐TB) and the rising incidence of nontuberculous mycobacterial (NTM) infections highlight the urgent need for innovative therapeutic strategies. Current treatments are prolonged, toxic, and increasingly compromised by resistance and limited diagnostic capacity.
Tânia Silva, Alessandra Aiello, Tonino Alonzi, M. Alice Carvalho, Vladimir Finger, Delia Goletti, Sven Hoffner, Yousra Kherabi, Jan Korabecny, Julia Kulczyńska, Agnieszka Kyzioł, Alicia Lacoma, Filomena Martins, Zorica Nanovic, Sepideh Hosseiniporgham, Martina Hrast Rambaher, Leonardo Antonio Sechi, Daria Smalchuk, Grażyna Stochel, Lydia Tabernero, Nancy L. Tateosian, Violeta Valcheva, Anamarija Zega, Mafalda Sarraguça   +23 more
wiley   +1 more source

An Economic Dilemma between Molecular Weapon Systems May Explain an Arachno-Atypical Venom in Wasp Spiders (Argiope bruennichi)

Biomolecules, 2020
Spiders use venom to subdue their prey, but little is known about the diversity of venoms in different spider families. Given the limited data available for orb-weaver spiders (Araneidae), we selected the wasp spider Argiope bruennichi for detailed ...
Tim Lüddecke, Björn M. von Reumont, Frank Förster, André Billion, Thomas Timm, Günter Lochnit, Andreas Vilcinskas, Sarah Lemke   +7 more
doaj   +1 more source

Open‐land‐derived agroforestry and effects of abandonment of management of the main crop on ecosystem services and woody plant diversity

PLANTS, PEOPLE, PLANET, EarlyView.
Tropical forests are rapidly declining. One promising strategy to reverse the loss of tropical forest is the establishment of agroforestry on open land. We combined interviews with biodiversity surveys to learn general lessons from success and nonsuccess stories of the establishment of open‐land‐derived coffee agroforests in one of the world's ...
Lucas M. Fonzaghi, Kristoffer Hylander, Thiago S. de Melo, Ayco J. M. Tack   +3 more
wiley   +1 more source

Assessing the potential for insecticide cross‐resistance to a novel insecticide in the Colorado potato beetle (Leptinotarsa decemlineata) using phenotypic and transcript expression analysis

Pest Management Science, EarlyView.
Phenotypic and transcriptional responses to imidacloprid and isocycloseram were examined across U.S. populations of the Colorado potato beetle, showing evidence of phenotypic cross‐resistance alongside population‐level variation in detoxification gene expression.
Emma E. Terris, Benjamin Z. Bradford, Faith Kulzer, Justin Clements, Kurt H. Lamour, Sean D. Schoville, Russell L. Groves   +6 more
wiley   +1 more source

Peptide‐based antibacterial nanoplatforms: Design principles, stimuli‐regulated behaviors, and applications

Responsive Materials, EarlyView.
Peptide‐based antibacterial nanoplatforms, encompassing self‐assembled peptides and peptide‐engineered inorganic, polymeric, and lipid nanocarriers, are systematically reviewed. The article highlights design principles and stimuli‐responsive regulation for improving peptide stability, delivery efficiency, and antibacterial performance.
Peng Tan, Chenlong Zhou, Shuaikang Yang, Zhenduo Chen, Guanghui Zhao, Qi Tang, Haoyu Yan, Feng Li, Xi Ma   +8 more
wiley   +1 more source

Artemia salina Toxicity Assay: Standardization in a 24‐Well Microplate

Environmental Toxicology, EarlyView.
ABSTRACT Bioassays with Artemia sp. are widely used in aquatic, environmental, and human toxicology as an initial tool to investigate the toxicity of plant extracts, isolated compounds, drugs, and products of natural or synthetic origin. These assays allow for the estimation of the median lethal concentration (LC50) and guide subsequent studies in ...
Matheus Pires Miranda, Natalie Petrovna Semanovschi, Roseane Santos de Souza, Angélica Maria Lucchese, Luzimar Gonzaga Fernandez   +4 more
wiley   +1 more source