Engineering the Rod of Asclepius – A Biochemical Investigation of Snake Venom Components and their Application as Potential Cancer Treatments [PDF]
, 2019 In the wild, venom is crucial to many snakes’ success as predators. While antivenin research focuses on combatting venoms’ abilities to disrupt physiological processes, new studies are attempting to manipulate these same abilities into anticancer ...
Pena, Noel
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The Northern Widow Spider, Latrodectus Variolus (Araneae: Theridiiae), in Michigan [PDF]
, 2017 Until recently the species of widow spider occurring in Michigan was considered a variant of the black widow, Latrodectus mactans (Fabricius). Levi (1959) summarized and revised the worldwide genus Latrodectus, placing the southern areas of Illinois ...
Wilson, Louis F
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Peptide Toxins in Solitary Wasp Venoms
Toxins, 2016 Solitary wasps paralyze insects or spiders with stinging venom and feed the paralyzed preys to their larva. Accordingly, the venoms should contain a variety of constituents acting on nervous systems.
K. Konno, Kohei Kazuma, K. Nihei
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Crotalus atrox venom preconditioning increases plasma fibrinogen and reduces perioperative hemorrhage in a rat model of surgical brain injury. [PDF]
, 2017 Perioperative bleeding is a potentially devastating complication in neurosurgical patients, and plasma fibrinogen concentration has been identified as a potential modifiable risk factor for perioperative bleeding.
Applegate, Richard +12 more
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Toxins, 2016 Australia is the stronghold of the front-fanged venomous snake family Elapidae. The Australasian elapid snake radiation, which includes approximately 100 terrestrial species in Australia, as well as Melanesian species and all the world’s true sea snakes,
Timothy N. W. Jackson +16 more
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Low-level laser therapy decreases local effects induced by myotoxins isolated from Bothrops jararacussu snake venom [PDF]
, 2010 The prominent myotoxic effects induced by Bothrops jararacussu crude venom are due, in part, to its polycationic myotoxins, BthTX-I and BthTX-II. Both myotoxins have a phospholipase A2 structure: BthTX-II is an active enzyme Asp-49 PLA2, while BthTX-I is
BARBOSA, AM +6 more
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Biochemical and immunochemical characterization of venoms from snakes of the genus Agkistrodon
Toxicon: X, 2019 In the present work, venoms from five species of the genus Agkistrodon were evaluated in terms of their enzymatic (Phospholipase A2 and caseinolytic) and biological (edema forming, hemorrhagic, procoagulant and lethal) effects.
Luis Román-Domínguez +8 more
doaj +1 more source
Evolution of separate predation- and defence-evoked venoms in carnivorous cone snails
Nature Communications, 2014 Venomous animals are thought to inject the same combination of toxins for both predation and defence, presumably exploiting conserved target pharmacology across prey and predators.
S. Dutertre +11 more
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Post-transcriptional Mechanisms Contribute Little to Phenotypic Variation in Snake Venoms
G3: Genes, Genomes, Genetics, 2015 Protein expression is a major link in the genotype–phenotype relationship, and processes affecting protein abundances, such as rates of transcription and translation, could contribute to phenotypic evolution if they generate heritable variation.
D. Rokyta, Mark J. Margres, Kate Calvin
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Bioactive Components in Fish Venoms
Toxins, 2015 Animal venoms are widely recognized excellent resources for the discovery of novel drug leads and physiological tools. Most are comprised of a large number of components, of which the enzymes, small peptides, and proteins are studied for their important ...
R. Ziegman, P. Alewood
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