Results 141 to 150 of about 63,437 (344)
Annals of Gastroenterological Surgery, EarlyView.The association between BMD reduction during NAC and the worse prognosis remains unknown, although NAC followed by esophagectomy is a standard treatment for advanced ESCC. This study appeared that BMD massive reduction was an independent prognostic factor on OS (HR, 3.30; 95% confidence interval [CI], 1.69–6.55) and RFS (HR, 2.08; 95% CI, 1.19–3.63 ...
Kazuhide Sato +11 more
wiley +1 more source
Can Large Language Models Design Biological Weapons? Evaluating Moremi Bio [PDF]
arXivAdvances in AI, particularly LLMs, have dramatically shortened drug discovery cycles by up to 40% and improved molecular target identification. However, these innovations also raise dual-use concerns by enabling the design of toxic compounds. Prompting Moremi Bio Agent without the safety guardrails to specifically design novel toxic substances, our ...
arxiv
Differentiation of toxicity properties of some social aculeate venoms (Hymenoptera, Aculeata) [PDF]
, 2000 Results of the investigations of toxicity properties of some social Aculeata venoms were presented. The action of crude venoms of six aculeate species: Apis mellifera, Bomhus sp., Vespa crabro, Vespula germanica, Vespula vulgaris, Polistes sp. on human
Nadolski, Jerzy
core
Construction of Active Sites‐Accessible Au8 Clusters for Intensive Tumor Pyroptosis
Aggregate, EarlyView.Ethynylferrocene (EFc) was utilized to engineer molecular‐like gold nanoclusters (NCs) with accessibly catalytic centers, resulting in NCs exhibiting excellent peroxidase‐like activity and the ability to radiosensitize, leading to the production of intracellular oxidative stress and activation of pyroptosis.
Qiu‐Xu Zang +8 more
wiley +1 more source
Process Resilience under Optimal Data Injection Attacks
AIChE Journal, EarlyView.Abstract In this article, we study the resilience of process systems in an information‐theoretic framework, from the perspective of an attacker capable of optimally constructing data injection attacks. The attack aims to distract the stationary distributions of process variables and stay stealthy, simultaneously.
Xiuzhen Ye, Wentao Tang
wiley +1 more source
Angewandte Chemie, EarlyView.Human synenkephalin [1–53] (hSYN), an analogue peptide of shrew saliva neurotoxins, was synthesized and its structural characteristics studied. Synthetic hSYN potently activated the T‐type voltage‐gated Ca channel hCav3.2 but did not paralyze mealworms. These findings offer new insight into neurological disorder treatment and evolutionary mechanisms of
Ryo Fukuoka +5 more
wiley +2 more sources
Advanced Intelligent Systems, EarlyView.Random telegraph noise (RTN) characteristics of memristor depend on external environmental conditions. To avoid these bias‐dependent characteristics, a true random number generator circuit using the RTN current fluctuations of memristor is presented with an edge detection circuit and counter, and bias independence is experimentally demonstrated for ...
Jinwoo Park, Hyunjoong Kim, Hyungjin Kim
wiley +1 more source
Fluid ejections in nature [PDF]
arXivFrom microscopic fungi to colossal whales, fluidic ejections are a universal and intricate phenomenon in biology, serving vital functions such as animal excretion, venom spraying, prey hunting, spore dispersal, and plant guttation. This review delves into the complex fluid physics of ejections across various scales, exploring both muscle-powered active
arxiv