Results 161 to 170 of about 53,540 (244)

Characterization of di‐gital, tri‐gital, and tetra‐gital temporal movement of systolic blood pressure on the arterial pulse waveform of rats at different vascular stiffness

open access: yesAnimal Models and Experimental Medicine, EarlyView.
The example of the time dependent fluctuation of systolic pressure on rat arterial pulse waveform in ms. The four levels of the systolic pressure fluctuation show di‐gital, tri‐gital and tetra‐gital fluctuation. The red dots represent particular heartbeats. Abstract Background An arterial stiffness is an indicator of many cardiovascular diseases.
Anton Misak   +3 more
wiley   +1 more source

Resilience to Endoplasmic Reticulum Stress Mitigates Membrane Hyperexcitability Underlying Late Disease Onset in a Murine Model of SCA6

open access: yesAnnals of Neurology, EarlyView.
Objective An enduring puzzle in many inherited neurological disorders is the late onset of symptoms despite expression of function‐impairing mutant protein early in life. We examined the basis for onset of impairment in spinocerebellar ataxia type 6 (SCA6), a canonical late‐onset neurodegenerative ataxia which results from a polyglutamine expansion in ...
Haoran Huang   +10 more
wiley   +1 more source

Myelitis‐Predominant Aggressive Phenotype: Unveiling Unique Patterns of Late‐Onset Neuromyelitis Optica Spectrum Disorders

open access: yesAnnals of Neurology, EarlyView.
Objective The objective of this study was to compare clinical features and prognosis of late‐onset neuromyelitis optica spectrum disorder (LO‐NMOSD, onset age ≥60 years) with adult‐onset NMOSD (AO‐NMOSD, onset age 18–59 years), and to provide insights for individualized management in elderly patients.
Ya‐Lan Pu   +15 more
wiley   +1 more source

Implantable Drug Delivery Systems for Skeletal Muscles and Eyes

open access: yesAdvanced NanoBiomed Research, EarlyView.
This review highlights the different types of recent implantable drug delivery systems (IDDS) fabricated for a use with skeletal muscles, and with eyes. It presents the developments already made and the current research directions, showing the evolution of IDDS and their great diversity.
Serge Ostrovidov   +8 more
wiley   +1 more source

Contribution of the Basophil Activation Test in the Diagnosis of Wasp Venom Allergy and Follow-Up of Venom Immunotherapy [PDF]

open access: bronze, 2006
Didier G. Ebo   +6 more
openalex   +1 more source

Dual‐Channel Fluorescence Assays with Supramolecular Host‐Dye Reporter Pairs for Membrane Activity Mapping of Peptides

open access: yesAngewandte Chemie International Edition, EarlyView.
Membrane‐active peptides (MAPs) such as cell‐penetrating peptides (CPPs) and antimicrobial peptides (AMPs) can translocate across lipid membranes and create membrane pores. The combination of a dye efflux and a supramolecular tandem membrane assay in a dual‐channel format enables an advanced mechanistic characterization and an exploration of the ...
Mohammad A. Alnajjar   +8 more
wiley   +1 more source

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