Results 51 to 60 of about 551,358 (298)

β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations

open access: yesAdvanced Biology, Volume 9, Issue 3, March 2025.
Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio   +11 more
wiley   +1 more source

Advanced Flame Retardant Strategies and Fire Performance Assessment for Safer Photovoltaics in Buildings: A Two‐Part Review

open access: yesAdvanced Functional Materials, EarlyView.
The integration of photovoltaic (PV) systems into building structures introduces distinct fire risks with critical implications for occupant safety. This review examines the key fire hazards associated with PV implementation and explores mitigation strategies, including flame‐retardant additives.
Florian Ollagnon   +7 more
wiley   +1 more source

Modeling of air flow in industrial rooms

open access: yesSelected Scientific Papers: Journal of Civil Engineering, 2018
The article is devoted to the air distribution in a room by swirl and laying air jets. Dynamic parameters of air flow that is created due to swirl and laying air jets at their leakage in a room has been determined.
Yurkevych Yuriy   +2 more
doaj   +1 more source

Heat demand uncertainty evaluation of typical multi‐flat panel building

open access: yesJournal of Civil Engineering and Management, 2006
Heat consumption of similar buildings under the same climatic conditions normally shows different values. This phenomenon has not been adequately explored yet.
Egle Jaraminiene, Egidijus Juodis
doaj   +1 more source

Next‐Generation Bio‐Reducible Lipids Enable Enhanced Vaccine Efficacy in Malaria and Primate Models

open access: yesAdvanced Functional Materials, EarlyView.
Structure–activity relationship (SAR) optimization of bio‐reducible ionizable lipids enables the development of highly effective lipid nanoparticle (LNP) mRNA vaccines. Lead LNPs show superior tolerability and antibody responses in rodents and primates, outperforming approved COVID‐19 vaccine lipids.
Ruben De Coen   +30 more
wiley   +1 more source

A Bespoke Programmable Interpenetrating Elastomer Network Composite Laryngeal Stent for Expedited Paediatric Laryngotracheal Reconstruction

open access: yesAdvanced Functional Materials, EarlyView.
A programmable interpenetrating double‐network architecture, created via 3D‐TIPS printing and resin infusion, synergistically combines thermoplastic and thermosetting elastomers to balance structural rigidity and surface softness—crucial for paediatric laryngeal stents.
Elizabeth F. Maughan   +14 more
wiley   +1 more source

Hygrothermal Risk in Museum Buildings Located in Moderate Climate

open access: yesEnergies, 2020
Works of art are sensitive to environmental factors—mainly temperature and relative humidity—which, when stable, are generally recommended as ideal protection conditions, but in historical museum buildings, the required conditions are ...
Joanna Ferdyn-Grygierek   +5 more
doaj   +1 more source

A Scalable, Durable, Fire‐Safe All‐Day Passive Radiative Cooling Coating for Sustainable Buildings

open access: yesAdvanced Functional Materials, EarlyView.
This study reports a scalable, durable coating that combines a fire‑retardant copolymer adhesive, hollow glass microspheres, and boron oxide to achieve passive radiative cooling with over 94% solar reflectance and >95% mid‑infrared emissivity. The coating maintains performance after UV and rain exposure and exhibits UL‑94 V‑0 fire resistance, enabling ...
Zhewen Ma   +8 more
wiley   +1 more source

Search for optimal solution of public building renovation in terms of life cycle

open access: yesJournal of Environmental Engineering and Landscape Management, 2010
Climate change became a priority issue on the agenda of the energy and environmental policy of the European Union. Energy efficiency and renewable energy are the main pillars to cope with climate change.
Lina Užšilaitytė   +1 more
doaj   +1 more source

From In‐Silico Optimized Microfabrication to Experimental Validation: Engineering a Tridimensional Epi‐Intraneural Interface

open access: yesAdvanced Functional Materials, EarlyView.
An epi‐intraneural interface is developed through in silico optimization and a novel tridimensional microfabrication pipeline. The device integrates penetrating and epineural contacts on a flexible substrate. Mechanical, electrochemical, and in vivo testing in rat and pig reveal robust implantation, low‐threshold activation, and site‐dependent ...
Federico Ciotti   +14 more
wiley   +1 more source

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