Results 71 to 80 of about 1,445,190 (422)

Thermal proteome profiling and proteome analysis using high‐definition mass spectrometry demonstrate modulation of cholesterol biosynthesis by next‐generation galeterone analog VNPP433‐3β in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Elevated level of cholesterol is positively correlated to prostate cancer development and disease severity. Cholesterol‐lowering drugs, such as statins, are demonstrated to inhibit prostate cancer. VNPP433‐3β interrupts multiple signaling and metabolic pathways, including cholesterol biosynthesis, AR‐mediated transcription of several oncogenes, mRNA 5′
Retheesh S. Thankan   +10 more
wiley   +1 more source

Improving the quality of biogas fuel combustion in a household gas burner [PDF]

open access: yesBIO Web of Conferences
The technology of energy production from waste of various origins is one of the most promising areas of the energy industry. Improving the efficiency of using alternative energy sources, as well as reducing the negative impact of organic waste of various
Ramazanov R.S.   +2 more
doaj   +1 more source

Performance of natural, exhaust, demand controlled exhaust and heat recovery residential ventilation systems as prescribed by the standards in 5 European countries [PDF]

open access: yes, 2013
Over the last decades, residential ventilation standards have been integrated in most of the buildings codes of European countries. Contrarily to the consolidation effort in the development of the nonresidential ventilation standard EN 13779, most of the
Janssens, Arnold   +3 more
core   +1 more source

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model

open access: yesMolecular Oncology, EarlyView.
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit   +19 more
wiley   +1 more source

Ultra-open High-efficiency Ventilated Metamaterial Absorbers with Customized Broadband Performance [PDF]

open access: yesExtreme Mechanics Letters, 39, 100786 (2020), 2019
High-efficiency absorption of low-frequency sounds (< 1000 Hz) while maintaining a free flow of fluids remains a significant challenge in acoustical engineering due to the rigid trade-off between absorption and ventilation performances. Although ongoing advances in acoustic metamaterials have unlocked unprecedented possibilities and various ...
arxiv   +1 more source

Influence of Visitors’ Flows on Indoor Air Quality of Museum Premises

open access: yesSelected Scientific Papers: Journal of Civil Engineering, 2012
The article considers the influence of visitors’ flows on indoor air quality of museum premises and work of ventilation and air conditioning systems.
Dovgaliuk Volodymyr, Lysak Pavlo
doaj   +1 more source

Environmental and Health Effects of Ventilation in Subway Stations: A Literature Review

open access: yesInternational Journal of Environmental Research and Public Health, 2020
Environmental health in subway stations, a typical type of urban underground space, is becoming increasingly important. Ventilation is the principal measure for optimizing the complex physical environment in a subway station.
Yueming Wen   +5 more
semanticscholar   +1 more source

Ventilation [PDF]

open access: yesPublic Health, 1901
n ...
openaire   +1 more source

Early metastasis is characterized by Gr1+ cell dysregulation and is inhibited by immunomodulatory nanoparticles

open access: yesMolecular Oncology, EarlyView.
Breast cancer metastasis is associated with myeloid cell dysregulation and the lung‐specific accumulation of tumor‐supportive Gr1+ cells. Gr1+ cells support metastasis, in part, through a CHI3L1‐mediated mechanism, which can be targeted and inhibited with cargo‐free, polymeric nanoparticles.
Jeffrey A. Ma   +9 more
wiley   +1 more source

Heating of the Natural Gas at the Gas-distributive Installation

open access: yesSelected Scientific Papers: Journal of Civil Engineering, 2012
Heating of natural gas on the gas-distributive installations is carried out for prevention of creation of gas hydrates in gas pressure controller. There are a few methods of heating of natural gas: complete heating of gas and heating of gas pressure ...
Savchenko Olena   +2 more
doaj   +1 more source

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