Results 131 to 140 of about 16,700 (245)

Glucagon‐Like Peptide‐1 Agonist vs. Placebo and Pulmonary Decline After Open‐Heart Surgery: A Substudy of the GLORIOUS Randomised Clinical Trial

open access: yesActa Anaesthesiologica Scandinavica, Volume 70, Issue 6, July 2026.
ABSTRACT Background Postoperative pulmonary decline is an established complication of open‐heart surgery extending beyond the immediate postoperative phase. Inflammation‐mediated lung damage and ischaemia‐reperfusion injury secondary to extracorporeal circulation is a proposed pathophysiological driver. GLP‐1 receptor agonists (GLP‐1RA) have emerged as
Astrid Duus Mikkelsen   +9 more
wiley   +1 more source

Myosin Post‐Translational Modifications Associated With Critical Illness Myopathy

open access: yesActa Physiologica, Volume 242, Issue 7, July 2026.
ABSTRACT Background Critical illness myopathy is a common and devastating consequence of critical care, causing dramatic loss of muscle mass and function in intensive care unit patients. Functional deficits often exceed the loss in muscle mass and myosin content.
Fernando Ribeiro   +9 more
wiley   +1 more source

Effects of Inspiratory Muscle Training on Weaning from Mechanical Ventilation and ICU Length of Stay

open access: yes, 2015
Advised by Fred Carey, PT, PhDBackground/Purpose: Prolonged mechanical ventilation produces staggering health care costs and overall poor patient outcomes short and long term.
Drinnan, Violet
core  

Mapping the murine TMJ glenoid fossa over development, homeostasis and in response to disease

open access: yesJournal of Anatomy, Volume 249, Issue 1, Page 85-96, July 2026.
The fibrocartilage of the murine glenoid fossa and condyle of the temporomandibular joint are shown to form at distinct times with distinct molecular identities. Changes in the condyle during disease lead to remodelling of the fossa to maintain joint alignment.
Ticha Tuwatnawanit   +4 more
wiley   +1 more source

"Do as you usually do" : ICU nurses´ perception of ventilator weaning

open access: yes, 2013
Bakgrund: För tidig eller för sen urträning från ventilator kan ge negativa konsekvenser för patienten, därför bör det identifieras när patientens tillstånd tillåter detta.
Tavallaey Roodsari, Leila   +1 more
core  

Glucocorticoid Receptor Translational Isoforms Generate Unique Glucocorticoid Responses in the Mouse Brain

open access: yesThe FASEB Journal, Volume 40, Issue 12, 30 June 2026.
GR‐A knockin mice were generated that express the classic full‐length glucocorticoid receptor (GR‐A) but lack the highly conserved translational isoforms GR‐B, GR‐C1, GR‐C2, GR‐C3, GR‐D1, GR‐D2, and GR‐D3 that have progressively shorter N‐terminal transactivation domains (NTDs).
Robert H. Oakley   +8 more
wiley   +1 more source

Correlation Between Adherence to a Ventilator Weaning Protocol and Successful Extubations in an Intensive Care Nursery

open access: yes, 2012
Presented at: American Association of Respiratory Care. Background Chronic lung disease (CLD) is a multi-factorial respiratory disease of the preterm neonate for which mechanical ventilation is a significant contributor.
Nawab, MD, Ursula   +3 more
core  

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, Volume 20, Issue 6, Page 1473-1493, June 2026.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

Application of Modified Ventilator Bundle and Its Effect on Weaning and Ventilation Days among Critical Ill Patients

open access: yes, 2020
Context: Modified ventilator bundle is the group of interventions supported by evidence to prevent ventilator-associated pneumonia and other related complications that commonly occurred in mechanically ventilated patients.
Mohammad, Sahar   +4 more
core  

Effect of inspiratory muscle strength training on ventilator weaning: An Experimental study [PDF]

open access: yes, 2011
OBJECTIVES: To analyze the effect of Inspiratory Muscle Strength Training, to improve respiratory muscle strength & pulmonary function and thereby prolonging spontaneous breathing periods to facilitate ventilator weaning. STUDY DESIGN: Pre-test & Post-
Hemalatha, C
core  

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