Results 41 to 50 of about 271,842 (268)
BMC Public Health, 2021 Background To evaluate global burden of refraction disorders by year, age, region, gender, socioeconomic status and other national characteristics in terms of disability adjusted life years (DALYs) and prevalence from Global Burden of Disease (GBD) study
He-Yan Li +8 more
doaj +1 more source
Prospects of antineutrino detection as an IAEA verification metric for the disposition of weapons-grade plutonium in the United States [PDF]
, 2012 Thesis (S.M.)--Massachusetts Institute of Technology, Dept. of Nuclear Science and Engineering; and, (S.M. in Technology and Policy)--Massachusetts Institute of Technology, Engineering Systems Division, Technology and Policy Program, 2012.Cataloged from ...
Copeland, Christopher Michael, S.M. Massachusetts Institute of Technology
core
Timing verification of dynamically reconfigurable logic for Xilinx Virtex FPGA series [PDF]
, 2002 This paper reports on a method for extending existing VHDL design and verification software available for the Xilinx Virtex series of FPGAs. It allows the designer to apply standard hardware design and verification tools to the design of dynamically ...
Ian Robertson +7 more
core +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Event Order Abstraction for Parametric Real-Time System Verification [PDF]
, 2008 We present a new abstraction technique, event order abstraction (EOA), for parametric safety verification of real-time systems in which ``correct orderings of events'' needed for system correctness are maintained by timing constraints on the systems ...
Umeno, Shinya, Shinya Umeno
core +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
BMC Medical EducationObjective Ocular fundus disease is one of the most complex areas of ophthalmology and a difficulty in ophthalmic education and training. Fundus imaging is an essential tool and reliable method for teaching fundus diseases.
Shi Xuehui +4 more
doaj +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source