Results 51 to 60 of about 271,842 (268)

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Airworthiness verification of additive manufacturing technology for large integral metallic structure

Journal of Aeronautical Materials, 2019
In order to solve the problems existing in airworthiness verification of the large integral metallic structure for civil aircraft main bearing part, the airworthiness verification of the metallic structure additive manufacturing technology was carried ...
JIANG Wu, LIU Mujun, HAO Xiaoning, LUO Linyin   +3 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Prevalence and associated health and lifestyle factors of myopic maculopathy in northern China: the Kailuan eye study

BMC Ophthalmology, 2023
Background To evaluate the prevalence and associated health and lifestyle factors of myopic maculopathy (MM) in a northern Chinese industrial city. Methods The cross-sectional Kailuan Eye Study included subjects who participated in the longitudinal ...
Haiwei Wang, Jinqiong Zhou, Ya Xing Wang, Qian Wang, Yanni Yan, Xuan Yang, Jingyan Yang, Wenjia Zhou, Zihan Nie, Xuhan Shi, Haixia Ji, Yongpeng Zhang, Xuehui Shi, Wen-Bin Wei   +13 more
doaj   +1 more source

Innovative Energy and Environmental Technology Verification (EETV) Factsheet

, 2000
This document provides information regarding the Energy and Environmental Technology Verification (EETV) Program, the Verification/Certification Process, the role of the New Jersey Corporation for Advanced Technology, the three Tiers of the Technology ...

core   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

A prognostic model for uveal melanoma in Asian populations: a comparative analysis of clinical features and gene expression patterns using the TRACE and TCGA data

BMC Ophthalmology
Background Uveal melanoma (UM), the most common primary intraocular malignancy in adults, shows racial disparities in incidence, genetic drivers, and clinical outcomes.
Jingting Luo, Yuning Chen, Zhaoxun Feng, Haowen Li, Jingying Xiu, Yangxu Tao, Qiong Yang, Yueming Liu, Yang Li, Wenbin Wei   +9 more
doaj   +1 more source

Practical Verification of Concurrent Haskell Programs

, 2022
The formal verification of concurrent programs is of particular importance, because concurrent programs are notoriously difficult to test. Because Haskell is a purely functional language, it is relatively easy to reason about the correctness of such ...
Schifferstein, Michelle (author)
core  

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

Selection of Components in Compositional Verification of Safety Properties

, 2009
This report presents a two-step components selection method to compose the components for compositional verification. This method employs different methods for the selection of components to be composed during compositional verification.
Shi, Jinjian
core