Results 81 to 90 of about 945,119 (285)
Vertical foreclosure: a policy framework [PDF]
Whenever you phone your mother, switch on the light, or buy health insurance you purchase a service or product from a chain of vertically related industries.
Michiel Bijlsma +3 more
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Advanced Science, EarlyView.SerpinA3 acts as an endogenous TGF‐β receptor antagonist that binds to the extracellular domain of TGFR‐1, thereby preventing TGFR‐1–TGFR‐2 complex formation. This receptor‐level blockade suppresses TGF‐β/Smad2/3 signaling, attenuates cardiac fibroblast activation, and extracellular matrix deposition, and ultimately alleviates pressure overload–induced
Hui Wang +9 more
wiley +1 more source
Investment specificity, vertical integration and market foreclosure [PDF]
In this paper we consider the impact of vertical integration on a retailer's choices of product variety and specific, brand-supporting investment. In an incomplete contract environment, vertical merger encourages investment in integrated supply, and ...
Bickenbach, Frank, Williams, Iestyn
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Why Do Firms Impose Vertical Restraints? Evidence from Franchise Contracts
, 2019 Franchising is a business form in which one firm (the “franchisor”) licenses an- other firm or individual (the “franchisee”) to operate businesses using the franchisor’s trademarks and proprietary business methods.
Callaci, Brian
core +1 more source
Dual pKa Lipid Nanoparticles for Lung‐tropic mRNA Delivery and pH‐Programmed Endosomal Escape
Advanced Science, EarlyView.Lipid nanoparticles’ bottleneck lies in low endosomal escape efficiency and liver‐dominant delivery after intravenous administration. To overcome these limitations, we present a stepwise pH‐programmed lipid nanoparticle system enabled by our newly synthesized ionizable lipid.
Seong Gi Lim +12 more
wiley +1 more source
Vertical relationships between health insurers and healthcare providers [PDF]
The current institutional reforms in the Dutch healthcare sector may increase the extent of vertical relations (such as vertical contracts and vertical integration) between insurers and healthcare providers.
Michiel Bijlsma +2 more
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Advanced Science, EarlyView.The effect of ligand reactivity and carrier mechanics on thiol‐mediated uptake was investigated at the single‐molecule/particle level. The interaction kinetics of LA and AspA with membrane thiols were quantified; AspA is more efficient due to the higher binding affinity, greater binding stability, and more double‐disulfide binding, as well as greater ...
Zhuang Zhang +7 more
wiley +1 more source
SSRN Electronic Journal, 2019 This Essay, part of a symposium honoring Richard Posner’s thirty-six years on the bench, considers the influence of Judge Posner’s opinions about antitrust law. I focus on vertical restraints on distribution, an area of doctrine that was transformed over thirty years from a flat (per se) prohibition to a more lenient evaluation under the rule of reason.
openaire +2 more sources
Advanced Science, EarlyView.This graphical abstract illustrates how chaperone‐mediated autophagy (CMA) regulates intervertebral disc degeneration (IDD). Under normal homeostasis (B), CMA degrades cytoplasmic Midnolin (MIDN) to maintain proteostasis. Under inflammatory stress (A), impaired CMA leads to cytoplasmic MIDN accumulation.
Xianglong Chen +9 more
wiley +1 more source
Exclusive Safeguards and Technology Transfer: Subcontracting Agreements in Eastern Europe's Car Component Industry. [PDF]
We study the rationale for the use of exclusivity to protect transfer of technology in subcontracting agreements. The legal possibility arises through the EU Notice on Subcontracting.
H. Peter Møllgaard, Jochen Lorentzen
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