Results 201 to 210 of about 142,528 (291)

Advanced Dental Composite Technology via Bisilanized Dual‐Action Nanofillers for Biofilm Control

open access: yesAdvanced Science, EarlyView.
A multimodal research strategy has led to the development of an innovative resin‐based composite (RBC) with dual antibacterial action. The S_CM‐RBC formula showed strong antibiofilm activity, excellent mechanical strength, and biosafety. It effectively controlled oral bacteria in prevention of caries recurrence, and maintained pulp health in a rat ...
Chenmin Yao   +11 more
wiley   +1 more source

Palmitic Acid Promotes Antiviral Innate Immunity via ZDHHC20‐Mediated CMPK2 Palmitoylation

open access: yesAdvanced Science, EarlyView.
Metabolites have important functions in innate immune activation and regulation. Wang et al. uncover metabolic regulation of antiviral immunity through CMPK2 palmitoylation, which regulates CMPK2 mitochondrial localization and is promoted by ZDHHC20 but reversed by PPT1, inhibition of which antagonizes viral infection in mice.
Yujia Wang   +4 more
wiley   +1 more source

Sphingolipids containing very long-chain fatty acids regulate Ypt7 function during the tethering stage of vacuole fusion. [PDF]

open access: yesJ Biol Chem
Zhang C   +9 more
europepmc   +1 more source

Comparison of the Diagnostic Performance of C26:0-Lysophosphatidylcholine and Very Long-Chain Fatty Acids Analysis for Peroxisomal Disorders. [PDF]

open access: yesFront Cell Dev Biol, 2020
Jaspers YRJ   +9 more
europepmc   +1 more source

ACLY‐Driven Metabolic Reprogramming Promotes Histone Acetylation and Inflammation‐Associated Fibrosis in Chronic Kidney Disease

open access: yesAdvanced Science, EarlyView.
This study reveals a citrate–ACLY–H3K27ac metabolic–epigenetic axis driving inflammatory gene activation and kidney fibrosis, highlighting ACLY inhibition as a potential therapeutic strategy for chronic kidney disease (CKD). ABSTRACT The mechanisms by which metabolic stress drives epigenetic dysregulation and fibrosis in chronic kidney disease (CKD ...
Chunxiu Du   +15 more
wiley   +1 more source

Salmon in Pregnancy Study (SIPS): the effects of increased oily fish consumption on maternal nutrient intake, fatty acid status and immunity

open access: yes
The prevalence of childhood atopic diseases (eczema, asthma, allergies, hay-fever) has increased during the last 30 years. Epidemiological studies link higher fish intake during pregnancy with lower risk of atopy in the offspring.
Kremmyda, Lefkothea-Stella
core  

Very long chain fatty acids are an important marker of nutritional status in patients with anorexia nervosa: a case control study. [PDF]

open access: yesBiopsychosoc Med, 2020
Shimizu M   +9 more
europepmc   +1 more source

Prmt6 Deficiency or Inhibition Restores Microglial Homeostasis and Promotes Scar‐Limited Repair in Adult Spinal Cord Injury

open access: yesAdvanced Science, EarlyView.
After spinal cord injury, adult microglia remain persistently activated with chronic PRMT6 (protein arginine methyltransferase 6) upregulation. Prmt6 deficiency or inhibition reestablishes microglial homeostasis and promotes a scar‐limited repairment, enhancing axonal regrowth.
Weilin Peng   +9 more
wiley   +1 more source

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