Results 1 to 10 of about 2,902 (128)

Role of fatty acid elongases in determination of de novo synthesized monounsaturated fatty acid species[S] [PDF]

Journal of Lipid Research, 2010
Enhanced production of monounsaturated fatty acids (FA) derived from carbohydrate-enriched diets has been implicated in the development of obesity and insulin resistance.
Christopher D. Green, Cansel G. Ozguden-Akkoc, Yun Wang, Donald B. Jump, L. Karl Olson   +4 more
doaj   +4 more sources

Glioblastoma Multiforme Tumors in Women Have a Lower Expression of Fatty Acid Elongases ELOVL2, ELOVL5, ELOVL6, and ELOVL7 than in Men [PDF]

Brain Sciences, 2022
One line of research on the possible ways of inhibiting the growth of glioblastoma multiforme (GBM), a brain tumor with a very poor prognosis, is the analysis of its metabolism, such as fatty acid synthesis by desaturases and elongases.
Jan Korbecki, Donata Simińska, Dariusz Jeżewski, Klaudyna Kojder, Patrycja Tomasiak, Maciej Tarnowski, Dariusz Chlubek, Irena Baranowska-Bosiacka   +7 more
doaj   +2 more sources

A workflow to explore elongase diversity and extend the repertoire of fatty acids produced by Yarrowia lipolytica [PDF]

Microbial Cell Factories
Background Fatty acids display highly diverse structures that confer these molecules unique chemical properties and distinct physiological functions.
Jérémy Le Reun, Zélie Salvioli, Christian Croux, Jérémy Esque, Isabelle André, Florence Bordes   +5 more
doaj   +2 more sources

Paving the Way for Plant-Based Bioproduction of (Z)-13-Octadecenoic Moth Pheromone Compounds. [PDF]

Plant Biotechnol J
ABSTRACT Sex pheromones are eco‐friendly agents to control pest insects. Yet, the cost of synthetic pheromone production has restricted their use essentially to high value crops. Plant‐based bioproduction of pheromone compounds offers a promising and sustainable alternative, opening up for the deployment of pheromone‐mediated pest control also in row ...
Liu M, Li H, Jin H, Xiao Y, He P, Tan C, Wang HL, Lassance JM, Löfstedt C, Ding BJ.   +9 more
europepmc   +2 more sources

Assessing the Impact of Multigene Engineering on the Proteome: Omega-3 Camelina as a Case Study. [PDF]

Plant Biotechnol J
Plant Biotechnology Journal, Volume 24, Issue 10, Page 5480-5482, October 2026.
Zhang H, Napier JA, Theodoulou FL.
europepmc   +2 more sources

The repertoire of desaturases and elongases reveals fatty acid variations in 56 eukaryotic genomess⃞

Journal of Lipid Research, 2008
The repertoire of biosynthetic enzymes found in an organism is an important clue for elucidating the chemical structural variations of various compounds.
Kosuke Hashimoto, Akiyasu C. Yoshizawa, Shujiro Okuda, Keiichi Kuma, Susumu Goto, Minoru Kanehisa   +5 more
doaj   +3 more sources

Alpha-linolenic acid in cancer: a predictive fate-switch framework for tumor lipid reprogramming [PDF]

Frontiers in Oncology
Alpha-linolenic acid (ALA) is the major plant-derived omega-3 fatty acid in human diets, yet its relevance to cancer is often narrowly interpreted as a precursor to eicosapentaenoic acid and docosahexaenoic acid.
Jinrui Zheng, Xinxin Li, Hewei Gong, Jinshan Yang, Jingxuan Liu, Yuxin Lin, Yantao Lou, Jiahui Wang, Chunhua Lin   +8 more
doaj   +2 more sources

Characterization of Entamoeba fatty acid elongases; validation as targets and provision of promising leads for new drugs against amebiasis. [PDF]

PLoS Pathogens
Entamoeba histolytica is a protozoan parasite belonging to the phylum Amoebozoa that causes amebiasis, a global public health problem. E. histolytica alternates its form between a proliferative trophozoite and a dormant cyst. Trophozoite proliferation is
Fumika Mi-Ichi, Hiroshi Tsugawa, Tam Kha Vo, Yuto Kurizaki, Hiroki Yoshida, Makoto Arita   +5 more
doaj   +2 more sources

Engineering yeast for tailored fatty acid profiles [PDF]

Applied Microbiology and Biotechnology
The demand for sustainable and eco-friendly alternatives to fossil and plant oil-derived chemicals has spurred interest in microbial production of lipids, particularly triacylglycerols, fatty acids, and their derivatives.
Simon Kobalter, Tamara Wriessnegger, Harald Pichler   +2 more
doaj   +2 more sources

Molecular characterization of biosynthesis of polyunsaturated fatty acids during different developmental stages in the copepod Apocyclops royi

Aquaculture Reports, 2022
Copepod Apocyclops royi can biosynthesize long-chain polyunsaturated fatty acids (LC-PUFAs) when fed low-PUFA precursors. Previously, two elongases and two desaturases in the n-3 PUFA biosynthetic pathway were identified from A. royi.
Piti Amparyup, Supakarn Sungkaew, Walaiporn Charoensapsri, Paveena Tapaneeyaworawong, Parichat Chumtong, Patchari Yocawibun, Prarthana Pantong, Ratree Wongpanya, Chanprapa Imjongjirak, Sorawit Powtongsook   +9 more
doaj   +1 more source