Results 1 to 10 of about 402 (88)

Isolation and Characterization of the Diatom Phaeodactylum Δ5-Elongase Gene for Transgenic LC-PUFA Production in Pichia pastoris

Marine Drugs, 2014
The diatom Phaeodactylum tricornutum can accumulate eicosapentaenoic acid (EPA) up to 30% of the total fatty acids. This species has been targeted for isolating gene encoding desaturases and elongases for long-chain polyunsaturated fatty acid (LC-PUFA ...
Yangmin Gong, Xia Wan
exaly   +3 more sources

Effect of dietary fats on endogenous oleic acid biosynthesis in rat liver

Journal of Education, Health and Sport, 2022
Aim: Determine the effect of dietary fats with different fatty acid composition on the biosynthesis of oleic acid and its metabolic precursors in the liver .
A. Levitsky, V. Velichko, I. Selivanskaya, A. Lapinskaya   +3 more
doaj   +1 more source

Key Enzymes in Fatty Acid Synthesis Pathway for Bioactive Lipids Biosynthesis

Frontiers in Nutrition, 2022
Dietary bioactive lipids, one of the three primary nutrients, is not only essential for growth and provides nutrients and energy for life's activities but can also help to guard against disease, such as Alzheimer's and cardiovascular diseases, which ...
Xiao-Yan Zhuang, Yong-Hui Zhang, An-Feng Xiao, Ai-Hui Zhang, Bai-Shan Fang, Bai-Shan Fang   +5 more
doaj   +1 more source

Effect of dietary fat on the activity of palmitic acid elongase in the blood serum and liver of rats

Journal of Education, Health and Sport, 2022
Background. To determine the effect of dietary fats on the activity of palmitic acid elongase by two methods, using indicators of the fatty acid composition of lipids in the blood serum and liver of rats. Methods.
V. Velichko
doaj   +1 more source

Lipid profiles of Mediterranean moray, Muraena helena, European conger, Conger conger, and European eel, Anguilla anguilla (Actinopterygii: Anguilliformes) [PDF]

Acta Ichthyologica et Piscatoria, 2017
Background. The current topics in fish fatty acid (FA) research include qualitative comparisons, trophic transfer as nutritive sources of FA, evolutionary comparison of synthesis pathways, and potential application of most efficient fish desaturases and ...
D. Đikić, I. Landeka, R. Fuchs, D. Skaramuca, S. Matić-Skoko, P. Tutman, Z. Franić, I. Cvetković, B. Skaramuca   +8 more
doaj   +3 more sources

Elongases of Long-Chain Fatty Acids ELO2 and ELO9 Are Involved in Cuticle Formation and Function in Fecundity in the Yellow Fever Mosquito, Aedes aegypti

Insects, 2023
Long-chain fatty acid elongases (ELOs) play important roles in the metabolism of fatty acids in insects. In this study, the genes for two elongases from Aedes aegypti were identified, AeELO2 and AeELO9.
Jing Chen, Yu-Chen Wu, Jiu-Kai Chen, Xiao-Jing Zhu, David Merkler, Cheng-Hong Liao, Qian Han   +6 more
doaj   +1 more source

Targeted lipidomics reveals a novel role for glucosylceramides in glucose response

Journal of Lipid Research, 2023
The addition of excess glucose to the diet drives a coordinated response of lipid metabolism pathways to tune the membrane composition to the altered diet.
Mark A. Xatse, Andre F.C. Vieira, Chloe Byrne, Carissa Perez Olsen   +3 more
doaj   +1 more source

The Partitioning of Newly Assimilated Linoleic and α-Linolenic Acids Between Synthesis of Longer-Chain Polyunsaturated Fatty Acids and Hydroxyoctadecaenoic Acids Is a Putative Branch Point in T-Cell Essential Fatty Acid Metabolism

Frontiers in Immunology, 2021
Longer-chain polyunsaturated fatty acids (LCPUFAs) ≥20 carbons long are required for leukocyte function. These can be obtained from the diet, but there is some evidence that leukocytes can convert essential fatty acids (EFAs) into LCPUFAs. We used stable
Johanna von Gerichten, Annette L. West, Nicola A. Irvine, Elizabeth A. Miles, Philip C. Calder, Philip C. Calder, Karen A. Lillycrop, Barbara A. Fielding, Graham C. Burdge   +8 more
doaj   +1 more source

Apocryphal FADS2 activity promotes fatty acid diversification in cancer

Cell Reports, 2021
Summary: Canonical fatty acid metabolism describes specific enzyme-substrate interactions that result in products with well-defined chain lengths, degree(s), and positions of unsaturation.
Reuben S.E. Young, Andrew P. Bowman, Elizabeth D. Williams, Kaylyn D. Tousignant, Charles L. Bidgood, Venkateswara R. Narreddula, Rajesh Gupta, David L. Marshall, Berwyck L.J. Poad, Colleen C. Nelson, Shane R. Ellis, Ron M.A. Heeren, Martin C. Sadowski, Stephen J. Blanksby   +13 more
doaj   +1 more source

Glioblastoma Multiforme Tumors in Women Have a Lower Expression of Fatty Acid Elongases ELOVL2, ELOVL5, ELOVL6, and ELOVL7 than in Men

Brain Sciences, 2022
One line of research on the possible ways of inhibiting the growth of glioblastoma multiforme (GBM), a brain tumor with a very poor prognosis, is the analysis of its metabolism, such as fatty acid synthesis by desaturases and elongases.
Jan Korbecki, Donata Simińska, Dariusz Jeżewski, Klaudyna Kojder, Patrycja Tomasiak, Maciej Tarnowski, Dariusz Chlubek, Irena Baranowska-Bosiacka   +7 more
doaj   +1 more source