Dual Fatty Acid Elongase Complex Interactions in Arabidopsis. [PDF]
Very long chain fatty acids (VLCFAs) are involved in plant development and particularly in several cellular processes such as membrane trafficking, cell division and cell differentiation.
Céline Morineau +9 more
doaj +8 more sources
Tackling functional redundancy of Arabidopsis fatty acid elongase complexes [PDF]
Very-long-chain fatty acids (VLCFA) are precursors for various lipids playing important physiological and structural roles in plants. Throughout plant tissues, VLCFA are present in multiple lipid classes essential for membrane homeostasis, and also ...
Marguerite Batsale +8 more
doaj +6 more sources
Paving the Way for Plant‐Based Bioproduction of (Z)‐13‐Octadecenoic Moth Pheromone Compounds [PDF]
ABSTRACT Sex pheromones are eco‐friendly agents to control pest insects. Yet, the cost of synthetic pheromone production has restricted their use essentially to high value crops. Plant‐based bioproduction of pheromone compounds offers a promising and sustainable alternative, opening up for the deployment of pheromone‐mediated pest control also in row ...
Mengyu Liu +9 more
wiley +2 more sources
Distinct associations between body mass index and polyunsaturated fatty acids in dementia with Lewy Bodies and Alzheimer’s disease [PDF]
Objective: We aimed to assess the association between body mass index and polyunsaturated fatty acids to determine potential links and metabolic differences between Alzheimer's disease and dementia with Lewy bodies.
Nicolás Castellanos-Perilla +8 more
doaj +2 more sources
A workflow to explore elongase diversity and extend the repertoire of fatty acids produced by Yarrowia lipolytica [PDF]
Background Fatty acids display highly diverse structures that confer these molecules unique chemical properties and distinct physiological functions.
Jérémy Le Reun +5 more
doaj +2 more sources
Enzymes enabling the biosynthesis of various C20 polyunsaturated fatty acids in a sea urchin Hemicentrotus pulcherrimus [PDF]
Sea urchins, integral to marine ecosystems and valued as a delicacy in Asia and Europe, contain physiologically important long-chain (>C20) polyunsaturated fatty acids (PUFA) in their gonads, including arachidonic acid (ARA, 20:4n-6), eicosapentaenoic ...
Yingying Peng, Yutaka Haga, Naoki Kabeya
doaj +2 more sources
Tissue-Specific Differences in Fatty Acid Content and Desaturase Activity Between the Liver and Spinal Cord of Diabetic ZDF Rats [PDF]
Imbalance in fatty acid (FA) metabolism is a critical factor in the development of type 2 diabetes (T2D). This study examined fatty acid composition and desaturase activities in the liver and spinal cord of male Zucker diabetic fatty (ZDF) rats, a ...
Katarína Orešanská +4 more
doaj +2 more sources
Dual Fatty Acid Elongase Complex Interactions in Arabidopsis
Very long chain fatty acids (VLCFAs) are required for the synthesis of triacylglycerols, waxes, phospholipids and sphingolipids. Fatty acyl chain length is essential for plant development in particular for membrane trafficking during cell division and cell differentiation [1–3].
Morineau, Céline +7 more
core +5 more sources
ELOVL5 Is a Critical and Targetable Fatty Acid Elongase in Prostate Cancer [PDF]
Abstract The androgen receptor (AR) is the key oncogenic driver of prostate cancer, and despite implementation of novel AR targeting therapies, outcomes for metastatic disease remain dismal. There is an urgent need to better understand androgen-regulated cellular processes to more effectively ...
Margaret M. Centenera +32 more
openaire +7 more sources
Fatty Acid Synthesis by Elongases in Trypanosomes [PDF]
All eukaryotic and prokaryotic organisms are thought to synthesize fatty acids using a type I or type II synthase. In addition, eukaryotes extend pre-existing long chain fatty acids using microsomal elongases (ELOs). We have found that Trypanosoma brucei, a eukaryotic human parasite that causes sleeping sickness, uses three elongases instead of type I ...
Lee, Soo Hee +3 more
openaire +2 more sources

