Results 41 to 50 of about 8,658 (206)

Cryptosporidium parvum Long-Chain Fatty Acid Elongase [PDF]

Eukaryotic Cell, 2007
ABSTRACT We report the presence of a new fatty acyl coenzyme A (acyl-CoA) elongation system in Cryptosporidium and the functional characterization of the key enzyme, a single long-chain fatty acid elongase (LCE), in this parasite.
Jason M, Fritzler, Jason J, Millership, Guan, Zhu   +2 more
openaire   +2 more sources

Functional characterisation of a Fads2 fatty acyl desaturase with delta6/delta8 activity and an Elovl5 with C16, C18 and C20 elongase activity in the anadromous teleost meagre (Argyrosomus regius) [PDF]

, 2013
The meagre, Argyrosomus regius, is a carnivorous fish with great potential to diversify finfish aquaculture in the Mediterranean. However, currently nothing is known about their essential fatty acid requirements.
Hontoria, Francisco, Navarro, Juan Carlos, Monroig, Oscar, Tocher, Douglas R, Tocher, Douglas R.   +4 more
core   +1 more source

Triangle of U Fatty Acid Elongase (FAE1) Phylogenetic Tree

, 2022
Alignment file and Newick tree for Fatty Acid Elongase (FAE1) orthologs among the Triangle of U species. To investigate orthologs among the Triangle of U species, phylogenetic trees were constructed for three agriculturally important genes: Flowering ...
Mia Swain (12552355)
core   +1 more source

Isolation and functional characterization of fatty acid Δ5-elongase gene from the liverwort Marchantia polymorpha L. [PDF]

, 2006
Bryophyte Marchantia polymorpha L. produces C22 very-long-chain polyunsaturated fatty acid (VLCPUFA). Thus far, no enzyme that mediates elongation of C20 VLCPUFAs has been identified in land plants.
Sakai, Yasuyoshi, Fukuzawa, Hideya, Ohyama, Kanji, Yamato, Katsuyuki T., Kohchi, Takayuki, Kajikawa, Masataka   +5 more
core   +1 more source

Examination of gammarid transcriptomes reveals a widespread occurrence of key metabolic genes from epibiont bdelloid rotifers in freshwater species

Open Biology, 2023
Previous data revealed the unexpected presence of genes encoding for long-chain polyunsaturated fatty acid (LC-PUFA) biosynthetic enzymes in transcriptomes from freshwater gammarids but not in marine species, even though closely related species were ...
Alberto Ribes-Navarro, Naoki Kabeya, L. Filipe C. Castro, André Gomes-dos-Santos, Miguel M. Fonseca, Hilke Alberts-Hubatsch, Francisco Hontoria, Juan C. Navarro, Óscar Monroig   +8 more
doaj   +1 more source

Tissue-specific, nutritional, and developmental regulation of rat fatty acid elongases

Journal of Lipid Research, 2005
Of the six fatty acid elongase (Elovl) subtypes expressed in mammals, adult rat liver expresses four subtypes: Elovl-5 > Elovl-1 = Elovl-2 = Elovl-6. Overnight starvation and fish oil-enriched diets repressed hepatic elongase activity in livers of adult ...
Yun Wang, Daniela Botolin, Barbara Christian, Julia Busik, Jinghua Xu, Donald B. Jump   +5 more
doaj   +1 more source

Polyunsaturated Fatty Acid (pufa) Elongase From Caenorhabditis Elegans (Patent CA 2365096 A1)

, 2000
A isolated polypeptide comprising a functional long chain polyunsaturated fatty acid (PUFA ...
Napier, J. A.
core   +2 more sources

Regulation of hepatic fatty acid elongase and desaturase expression in diabetes and obesity

Journal of Lipid Research, 2006
Fatty acid elongases and desaturases play an important role in hepatic and whole body lipid composition. We examined the role that key transcription factors played in the control of hepatic elongase and desaturase expression.
Yun Wang, Daniela Botolin, Jinghua Xu, Barbara Christian, Ernestine Mitchell, Bolleddula Jayaprakasam, Muraleedharan Nair, Jeffery M. Peters, Julia Busik, L. Karl Olson, Donald B. Jump   +10 more
doaj   +1 more source

PUFA synthase-independent DHA synthesis pathway in Parietichytrium sp. and its modification to produce EPA and n-3DPA

Communications Biology, 2021
Yohei Ishibashi and co-workers report that Parietichytrium sp. synthesizes DHA only via the elongase/desaturase pathway. They then engineered this thraustochytrid to produce EPA and n-3DPA by disrupting C20ELO and delta4 DES genes, respectively, in this ...
Yohei Ishibashi, Hatsumi Goda, Rie Hamaguchi, Keishi Sakaguchi, Takayoshi Sekiguchi, Yuko Ishiwata, Yuji Okita, Seiya Mochinaga, Shingo Ikeuchi, Takahiro Mizobuchi, Yoshitake Takao, Kazuki Mori, Kosuke Tashiro, Nozomu Okino, Daiske Honda, Masahiro Hayashi, Makoto Ito   +16 more
doaj   +1 more source

In planta analysis of the mode of action of cinmethylin and confirmation of fatty acyl‐ACP thioesterases (FATs) as primary site of action

Pest Management Science, EarlyView.
In planta analysis of the mode of action of cinmethylin and confirmation of fatty acyl‐ACP thioesterases (FATs) as primary site of action. Cinmethylin inhibits FATs, disrupting eukaryotic de novo lipid biosynthesis and causing defects in cell division, elongation and integrity. We confirm FATs as the primary site of action in planta.
Maximillian Pollmeier, Aisha Gerhardt, Janneke Hendriks, Katharina Kaprocki, Alexandra Zimmermann, Sarina Ruehm, Martina Marnet, Maria Stroe, Jorge Alfredo Rojas Biava, Clara Hofmann, Michael Betz, Sascha Schlaefer, Philipp Ternes, Jens Lerchl, Selene Garcia‐Hernandez, Philipp Johnen   +15 more
wiley   +1 more source