Results 51 to 60 of about 8,091 (214)

Elongase And Uses Thereof (Patent US 8119861 B2) [PDF]

, 2012
The invention relates to nucleic acid derived from Perkinsus marinus which encodes a 9-elongase, a Δ8-desaturase and a Δ5-desaturase enzyme.
Sayanova, O. V., Napier, J. A., Venegas, C. M.   +2 more
core  

PUFA synthase-independent DHA synthesis pathway in Parietichytrium sp. and its modification to produce EPA and n-3DPA

Communications Biology, 2021
Yohei Ishibashi and co-workers report that Parietichytrium sp. synthesizes DHA only via the elongase/desaturase pathway. They then engineered this thraustochytrid to produce EPA and n-3DPA by disrupting C20ELO and delta4 DES genes, respectively, in this ...
Yohei Ishibashi, Hatsumi Goda, Rie Hamaguchi, Keishi Sakaguchi, Takayoshi Sekiguchi, Yuko Ishiwata, Yuji Okita, Seiya Mochinaga, Shingo Ikeuchi, Takahiro Mizobuchi, Yoshitake Takao, Kazuki Mori, Kosuke Tashiro, Nozomu Okino, Daiske Honda, Masahiro Hayashi, Makoto Ito   +16 more
doaj   +1 more source

Stage‐Specific H3K14 and H3K23 Succinylation Orchestrates Insect Metamorphosis and Oogenesis

Advanced Science, EarlyView.
Stage‐specific succinylation of histone H3 at lysine 14 and 23 differentially controls insect metamorphosis and oogenesis through distinct GPCR‐PKC signaling cascades, revealing an evolutionarily conserved epigenetic mechanism that coordinates key life‐history traits.
Yu‐Pu Jing, Lunjie Li, Libin Yang, Lin‐Jie Zhang, Qiang Yan, Ci Zhang, Zanrong Wen, Guangze Yu, Qian Li, Shutang Zhou   +9 more
wiley   +1 more source

Higher Increases in Plasma n‐3 Polyunsaturated Fatty Acids Following Fish Oil Supplementation in Postmenopausal Females Compared With Age‐Matched Males

Lipids, EarlyView.
ABSTRACT The effects of fish oil supplementation on omega‐3 (n‐3) polyunsaturated fatty acids, particularly intermediates between eicosapentaenoic acid (EPA, 20:5n‐3) and docosahexaenoic acid (DHA, 22:6n‐3), that may provide valuable metabolic information, have not been fully characterized in older populations.
David C. R. Ku, Insaf Loukil, Annick Vachon, Mélanie Plourde, Adam H. Metherel   +4 more
wiley   +1 more source

Polysaturated Fatty Acid (pufa) Elongase From Caenorhabditis Elegans (Patent WO 2000/055330 A1) [PDF]

, 2000
A isolated polypeptide comprising a functional long chain polyunsaturated fatty acid (PUFA ...
Napier, J. A.
core  

Expression of fatty acyl desaturase and elongase genes, and evolution of DHA:EPA ratio during development of unfed larvae of Atlantic bluefin tuna (Thunnus thynnus L.) [PDF]

, 2011
The concentration of n-3 long-chain polyunsaturated fatty acids (LC-PUFA) in neural tissues is known to be crucial for effective prey capture from the time of first feeding in marine fish larvae. Furthermore, tissues of tunids, including Atlantic bluefin
Morais, S. (Sofía), Ortega-García, Aurelio, Toucher, D.R. (Douglas R.), Toucher, J.A., Ortega, Aurelio, Aurelio Ortega, Mourente, G. (Gabriel), Tocher, Jamie A, Toucher, J.A. (Jamie A.), Ortega-García, A. (Aurelio), Tocher, Douglas R, Morais, Sofia, Toucher, D.R., Jamie A. Tocher, Gabriel Mourente, Mourente, Gabriel, Sofia Morais, Douglas R. Tocher   +17 more
core   +1 more source

Continental accumulation of fads2 copy numbers allows sticklebacks to thrive across a diversity of nutritional landscapes

Oikos, EarlyView.
Nutrients, including vital organic compounds, vary in availability across ecosystems, with the potential to act as a source of selection for traits that increase nutrient acquisition and biosynthesis. Compared to freshwaters, marine ecosystems are richer in the omega‐3 long‐chain polyunsaturated fatty acid (n‐3 LC‐PUFA) docosahexaenoic acid (DHA ...
Cornelia W. Twining, Cameron M. Hudson, Jernej Bravničar, Antonella Carosi, Gaël P. J. Denys, Philine G. D. Feulner, Žiga Fišer, Hanna Rosinger, Verena Saladin, Linda Zanella, Davor Zanella, Catherine L. Peichel, Blake Matthews   +12 more
wiley   +1 more source

SMILE: Extraction‐free submicron‐resolution mapping of lipid chain length and unsaturation by stimulated Raman imaging

VIEW, EarlyView.
In this work, we develop submicron‐resolution mapping of intracellular lipid elements (SMILE) as an extraction‐free vibrational spectroscopic imaging platform based on hyperspectral stimulated Raman scattering microscopy with a spectral analysis pipeline for pixel‐resolved lipid profiling.
Yihui Zhou, Xiangjie Huang, Xingxin Liu, Ling Zhang, Jie Huang, Jing Zhao, Yongqing Zhang, Jin Zhang, Yanqing Gong, Delong Zhang, Hyeon Jeong Lee   +10 more
wiley   +1 more source

Elongase Gene And Production Of Delta9-polyunsaturated Fatty Acids (Patent US 2005/0089981 A1) [PDF]

, 2005
This invention relates to a new elongase gene having the sequence SEQ ID NO: 1 or its derivatives, to a gene construct comprising this sequence or its derivatives and to its use.
Napier, J. A., Qi, B., Lerchl, J., Lazarus, C.   +3 more
core  

Evolution of a fatty acyl–CoA elongase underlies desert adaptation in Drosophila

Science Advances, 2023
Traits that allow species to survive in extreme environments such as hot-arid deserts have independently evolved in multiple taxa. However, the genetic and evolutionary mechanisms underlying these traits have thus far not been elucidated. Here, we show that Drosophila mojavensis , a desert-adapted fruit fly species,
Zinan Wang, Jian Pu, Cole Richards, Elaina Giannetti, Haosu Cong, Zhenguo Lin, Henry Chung   +6 more
openaire   +2 more sources