Results 21 to 30 of about 2,715,237 (202)

Identification and Expression of a Rat Fatty Acid Elongase Involved in the Biosynthesis of C18 Fatty Acids [PDF]

Bioscience, Biotechnology, and Biochemistry, 2002
A major part of the palmitic acid (C16:0) generated by fatty acid synthase is converted into stearic acid (C18:0) via carbon chain elongation. Here, we describe the cloning and expression of a rat hepatic enzyme, rELO2, responsible for the elongation of C16:0, presumably at the condensing reaction.
INAGAKI, Katsuya, AKI, Tsunehiro, FUKUDA, Yoshihiro, KAWAMOTO, Seiji, SHIGETA, Seiko, ONO, Kazuhisa, SUZUKI, Osamu   +6 more
openaire   +2 more sources

Fatty acid elongase is required for shoot development in rice [PDF]

The Plant Journal, 2011
SummaryOrganisms are covered extracellularly with cuticular waxes that consist of various fatty acids. In higher plants, extracellular waxes act as indispensable barriers to protect the plants from physical and biological stresses such as drought and pathogen attacks.
Yukihiro, Ito, Fumiko, Kimura, Kazuma, Hirakata, Katsutoshi, Tsuda, Tomoaki, Takasugi, Mitsugu, Eiguchi, Kiyotaka, Nakagawa, Nori, Kurata   +7 more
openaire   +2 more sources

Estrogen Enhances the Expression of the Polyunsaturated Fatty Acid Elongase Elovl2 via ERα in Breast Cancer Cells. [PDF]

PLoS ONE, 2016
Endocrine therapy is the first-line targeted adjuvant therapy for hormone-sensitive breast cancer. In view of the potential anticancer property of the omega-3 polyunsaturated fatty acid docosahexaenoic acid (DHA) together with chemotherapy in estrogen ...
Amanda González-Bengtsson, Abolfazl Asadi, Hui Gao, Karin Dahlman-Wright, Anders Jacobsson   +4 more
doaj   +1 more source

The LXRB-SREBP1 network regulates lipogenic homeostasis by controlling the synthesis of polyunsaturated fatty acids in goat mammary epithelial cells

Journal of Animal Science and Biotechnology, 2022
Background In rodents, research has revealed a role of liver X receptors (LXR) in controlling lipid homeostasis and regulating the synthesis of polyunsaturated fatty acids (PUFA).
Wenying Zhang, Changhui Zhang, Jun Luo, Huifen Xu, Jianxin Liu, Juan J. Loor, Hengbo Shi   +6 more
doaj   +1 more source

Plasma Lipolysis and Changes in Plasma and Cerebrospinal Fluid Signaling Lipids Reveal Abnormal Lipid Metabolism in Chronic Migraine

Frontiers in Molecular Neuroscience, 2021
BackgroundLipids are a primary storage form of energy and the source of inflammatory and pain signaling molecules, yet knowledge of their importance in chronic migraine (CM) pathology is incomplete.
Katherine Castor, Jessica Dawlaty, Xianghong Arakaki, Xianghong Arakaki, Noah Gross, Yohannes W. Woldeamanuel, Michael G. Harrington, Michael G. Harrington, Michael G. Harrington, Robert P. Cowan, Alfred N. Fonteh, Alfred N. Fonteh   +11 more
doaj   +1 more source

Fatty Acid Desaturases And Elongases And Uses Thereof (Patent US 9493520 B2 ) [PDF]

, 2016
The invention provides isolated nucleic acid molecules which encode novel fatty acid desaturases and elongases from the organism Emiliana huxleyi. The invention also provides recombinant expression vectors containing desaturase or elongase nucleic acid ...
Sayanova, O. V., Napier, J. A., Bauer, J.   +2 more
core   +3 more sources

De novo synthesis of nervonic acid and optimization of metabolic regulation by Yarrowia lipolytica

Bioresources and Bioprocessing, 2023
Nervonic acid, a natural fatty acid compound and also a core component of nerve fibers and nerve cells, has been widely used to prevent and treat related diseases of the brain nervous system.
Xin-Ru Zhao, Xin-Liang Chen, Jing-Lin Yang, Qi Gao, Jiang-Ting Shi, Qiang Hua, Liu-Jing Wei   +6 more
doaj   +1 more source

Effects of Dietary α-Linolenic Acid Treatment and the Efficiency of Its Conversion to Eicosapentaenoic and Docosahexaenoic Acids in Obesity and Related Diseases

Molecules, 2022
The essential fatty acid alpha-linolenic acid (ALA) is present in high amounts in oils such as flaxseed, soy, hemp, rapeseed, chia, and perilla, while stearidonic acid is abundant in echium oil.
Marija Takic, Biljana Pokimica, Gordana Petrovic-Oggiano, Tamara Popovic   +3 more
doaj   +1 more source

Novel Fatty Acid Desaturases And Elongases And Uses Thereof (Patent US 2012/0124705 A1) [PDF]

, 2012
The invention provides isolated nucleic acid molecules which encode novel fatty acid desaturases and elongases from the organism Emiliana huxleyi. The invention also provides recombinant expression vectors containing desaturase or elongase nucleic acid ...
Sayanova, O. V., Napier, J. A., Bauer , J.   +2 more
core   +3 more sources

Elongases of Long-Chain Fatty Acids ELO2 and ELO9 Are Involved in Cuticle Formation and Function in Fecundity in the Yellow Fever Mosquito, Aedes aegypti

Insects, 2023
Long-chain fatty acid elongases (ELOs) play important roles in the metabolism of fatty acids in insects. In this study, the genes for two elongases from Aedes aegypti were identified, AeELO2 and AeELO9.
Jing Chen, Yu-Chen Wu, Jiu-Kai Chen, Xiao-Jing Zhu, David Merkler, Cheng-Hong Liao, Qian Han   +6 more
doaj   +1 more source