The Opposite Effects of High-Sucrose and High-Fat Diet on Fatty Acid Oxidation and Very Low Density Lipoprotein Secretion in Rat Model of Metabolic Syndrome [PDF]
, 2012 Monika Cahová +4 more
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Advanced Science, EarlyView.Genetic and pharmacological inhibition of SLC11A1 functioning as an H+/Fe2+ antiporter–mediated lysosomal iron accumulation in microglia promotes lysosomal lumen acidification, increases CTSD expression, enhances lysosomal myelin debris uptake and degradation, and promotes repair following white matter stroke. ABSTRACT White matter stroke (WMS) results
Lingling Qiu +11 more
wiley +1 more source
Lipids in Health and DiseaseReducing circulating lipid levels is the centerpiece of strategies for preventing and treating atherosclerotic cardiovascular disease (ASCVD). Despite many available lipid-lowering medications, a substantial residual cardiovascular risk remains.
Jingfei Chen +7 more
doaj +1 more source
Spotlight on very-low-density lipoprotein as a driver of cardiometabolic disorders: Implications for disease progression and mechanistic insights. [PDF]
Front Cardiovasc Med, 2022 Lee HC, Akhmedov A, Chen CH.
europepmc +1 more source
Advanced Science, EarlyView.It is revealed that a metabolic–stromal loop driven by oxLDL–OLR1–FOXM1–FGF19 signaling promotes progesterone resistance in endometrial cancer. OxLDL activates epithelial–fibroblast crosstalk, enhancing proliferation and hormonal insensitivity. Disruption of this circuit, especially with resveratrol, restores MPA sensitivity, highlighting a potential ...
Xingchen Li +9 more
wiley +1 more source
Identification of Dysbetalipoproteinemia by an Enhanced Sampson-NIH Equation for Very Low-Density Lipoprotein-Cholesterol. [PDF]
Front Genet, 2022 Sampson M +5 more
europepmc +1 more source
Apoprotein B-poor very low density lipoprotein in diabetic patients without hyperlipoproteinemia.
, 1982 Yoshisuke Maruhama +5 more
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Targeting Endothelial KDM5A to Attenuate Aging and Ameliorate Age‐Associated Metabolic Abnormalities
Advanced Science, EarlyView.This study identifies endothelial KDM5A as a key regulator of aging. KDM5A deficiency accelerates aging by enhancing H3K4me3‐mediated FABP4 expression, disrupting fatty acid metabolism, and promoting multi‐organ senescence. KDM5A restoration or FABP4 inhibition reverses these adverse effects and extends lifespan, positioning the KDM5A/FABP4 axis as a ...
Rifeng Gao +21 more
wiley +1 more source
Identification and Characterization of the Very-Low-Density Lipoprotein Receptor Gene from Branchiostoma belcheri: Insights into the Origin and Evolution of the Low-Density Lipoprotein Receptor Gene Family. [PDF]
Animals (Basel), 2023 Cao Y, Wang H, Jin P, Ma F, Zhou X.
europepmc +1 more source
Interaction of the Apoproteins of Very Low Density and High Density Lipoproteins with Synthetic Phospholipids [PDF]
, 1976 Maryvonne Rosseneu +4 more
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