Results 101 to 110 of about 15,156,730 (296)

Controllable Cascade Aggregation Ion Programmed Nanomachines and Simple Isolation Enable Tumor‐Derived Small Extracellular Vesicles Detection for Enhanced Breast Cancer Assessment

Advanced Science, EarlyView.
This study developed a convenient, enzyme‐free detection platform based on controllable aggregation ion nanomachines. Its favorable anti‐interference capacity and high sensitivity meet the detection requirements for clinical samples processed via a simple filtration method within 10 min.
Zhihao Zhang, Zijing Liu, Xiangyue Meng, Pengjun Jiang, Jie Qu, Yu Jiang, Binxu Qiu, Jie Chen, Piaopiao Chen   +8 more
wiley   +1 more source

H.E.L.P. LDL-apheresis clinical experience in Italy

, 2011
H.E.L.P. LDL-apheresis clinical experience in ItalyStefanutti Claudia, Shafii Mahnaz, Di Giacomo Serafina, Morozzi Claudia, Mazzilli Sara and the Italian Multicenter Study on Low-Density-Lipoprotein -Apheresis Working GroupExtracorporeal Therapeutic ...
MOROZZI, CLAUDIA, STEFANUTTI, Claudia, M. Shafii, DI GIACOMO, SERAFINA, The Italian Multicenter Study O. N. Low Density Lipoprotein Apheresis Working Group, S. Mazzilli   +5 more
core   +1 more source

HUBUNGAN PROFIL DAN RASIO TOTAL KOLESTEROL/ HIGH DENSITY LIPOPROTEIN, TRIGLISERIDA/ HIGH DENSITY LIPOPROTEIN, DAN LOW DENSITY LIPOPROTEIN / HIGH DENSITY LIPOPROTEIN DENGAN VESSEL DISEASE PADA PASIEN PENYAKIT JANTUNG KORONER [PDF]

, 2021
THE RELATION BETWEEN PROFILE AND RATIO OF TOTAL CHOLESTEROL/ HIGH DENSITY LIPOPROTEIN, TRIGLYCERIDE/ HIGH DENSITY LIPOPROTEIN, AND LOW DENSITY LIPOPROTEIN/ HIGH DENSITY LIPOPROTEIN ON VESSEL DISEASE IN CORONARY HEART DISEASE PATIENTS By Nur Faydotus ...
Nur, Faydotus Salsabila
core  

Hyperlipidemia and atherosclerosis associated with liver disease in ferrochelatase-deficient mice1

Journal of Lipid Research, 2001
Erythropoietic protoporphyria (EPP) is an inherited disorder of heme synthesis caused by deficiency of the mitochondrial enzyme ferrochelatase. EPP in humans is associated with liver disease, hypertriglyceridemia, and a low level of high density ...
Vincent W. Bloks, Torsten Plösch, Harry van Goor, Han Roelofsen, Juul Baller, Rick Havinga, Henkjan J. Verkade, Aad van Tol, Peter L.M. Jansen, Folkert Kuipers   +9 more
doaj   +1 more source

SR‐A3 Promotes USP18‐Mediated deISGylation of STING to Protect Against Myocardial Ischemia‐Reperfusion Injury

Advanced Science, EarlyView.
MI/RI is a major clinical challenge with high morbidity and mortality. This study demonstrates that SR‐A3 expression is downregulated in MI/RI, and its deletion exacerbates damage via the USP18/ISG15/STING axis, revealing SR‐A3 as a potential therapeutic target.
Yufei Han, Guolin Miao, Yinqi Zhao, Zhiyong Du, Kaikai Lu, Changqi Xiao, Aiden Xian, Jiaxin Duanmu, Zihao Zhou, Jinxuan Chen, Lianxin Zhang, Chao Zhai, Yitong Xu, Zhaoling Li, Xianqin Shen, Sijing Shi, Jingxuan Chen, Si Mei, Yuan Fang, Liwen Zheng, Ling Zhang, Yuhui Wang, Wei Huang, Erdan Dong, Xunde Xian   +24 more
wiley   +1 more source

Methylation at CPT1A locus is associated with lipoprotein subfraction profiles[S]

Journal of Lipid Research, 2014
Lipoprotein subfractions help discriminate cardiometabolic disease risk. Genetic loci validated as associating with lipoprotein measures do not account for a large proportion of the individual variation in lipoprotein measures.
Alexis C. Frazier-Wood, Stella Aslibekyan, Devin M. Absher, Paul N. Hopkins, Jin Sha, Michael Y. Tsai, Hemant K. Tiwari, Lindsay L. Waite, Degui Zhi, Donna K. Arnett   +9 more
doaj   +1 more source

SPARC Drives Podocyte Mitochondrial Damage and Ferroptosis in Diabetic Kidney Disease Following Klotho Deficiency

Advanced Science, EarlyView.
Klotho deficiency promotes podocyte mitochondrial dysfunction and ferroptosis through activation of the PKCα/CUX1/SPARC/TGFβ‐RII axis. SPARC emerges as a key mediator linking Klotho loss to podocyte injury in DKD and other kidney injury models, suggesting broader implications for CKD progression.
Qing Yang, Huimin Jiang, Chenyang Xiong, Xindi Zhou, Qinqin Tan, Han Xiao, Lan Qiu, Chun Gan, Yaxi Chen, Haiping Yang, Wei Jiang, Qiu Li   +11 more
wiley   +1 more source

Relationship of Serum Low-Density Lipoproteins and Very Low-Density Lipoproteins to the Android Fat Pattern of Adult Males [PDF]

, 1991
This study was designed to further substantiate previous associations found between the android pattern of fat distribution and low-density lipoprotein cholesterol and very-low density lipoprotein cholesterol in adult ...
Steele, Candace Jean Wilson
core  

Fatty acids from Very Low-Density Lipoprotein Lipolysis Products Induce Lipid Droplet Accumulation in Human Monocytes

, 2010
den Hartigh LJ, Connolly-Rohrbach JE, Fore S, Huser T, Rutledge JC. Fatty acids from Very Low-Density Lipoprotein Lipolysis Products Induce Lipid Droplet Accumulation in Human Monocytes. J. Immunol.
Connolly-Rohrbach, J.E., Huser, Thomas ; https://orcid.org/, den Hartigh, L.J., Fore, S., Rutledge, J.C.   +4 more
core   +1 more source

Compact 9dBEs Enable Efficient and Precise Genome Editing in Mammalian Cells and In Vivo

Advanced Science, EarlyView.
As a compact type II‐D system, the Cas9d‐based platform holds great potential for in vivo applications. Through rational engineering, its derived base editors (9dBEs) enable efficient disease modeling while facilitating single‐vector AAV delivery for in vivo genome editing. These miniature tools offer a robust strategy for basic research and biomedical
Qingquan Xiao, Zhijin Tian, Luqi Weng, Kun Xu, Dingyi Han, Zhaowei Wu, Junnan Li, Shangpu Li, Qijing Zhang, Xiaohui Zhao, Guoling Li, Yinghui Wei, Zhen Gu   +12 more
wiley   +1 more source